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The map label for this gene is aroK [H]

Identifier: 119716640

GI number: 119716640

Start: 2573458

End: 2574009

Strand: Direct

Name: aroK [H]

Synonym: Noca_2413

Alternate gene names: 119716640

Gene position: 2573458-2574009 (Clockwise)

Preceding gene: 119716639

Following gene: 119716641

Centisome position: 51.62

GC content: 74.28

Gene sequence:

>552_bases
GTGACCGGACCCGCACGCCCCCGCGTCGTCCTGGTCGGGCCGATGGGGGCCGGCAAGACCACCGTCGCCCGGCTGCTGGC
CGACGCCTGGGGCACCGGGGTCCGGGACACGGACCACGACGTCGAGTCGGCCGAGGGTCGGACCATCTCCGACATCTTCG
TGGACTCCGGCGAGGGCGCCTTCCGAGACCTGGAGCGACGAGCGGTCGCGGCCGCGTTGCGCGAGCACGACGGCGTGCTC
GCGCTGGGCGGGGGAGCCGTGCTGGACCCTGGGACCCGCGACCTGCTGGCCGGCCACCGGGTCGTGTTCCTGCGGGTCGG
CCTCTCCGACGCCGTCAAGCGAGTCGGCCTCGGCGTCGCCCGCCCGCTGCTCCTCGGCAACGTCCGCGGACGGATCAAGG
CGCTCCTCGACGAGCGCACCCCCATCTACGAGTCGGTCGCGACCTTGGTCGTGGACACCGACGGCCGCAGCCCCGAGGAT
GTCGCCCAGGAGATCCGCGCTGCACTCGACGGGCCTGCGCTCGACGGGTCGGCGCTGGAGGGGGAAGCATGA

Upstream 100 bases:

>100_bases
CGCTGGTGCTCGCCGACGCCGTCCTGGAGAAGTTCGGGGGCGACTCGGTGCGCGAGACCCGCCGCAACGCGGAGGGCTAC
CTGGACACCCTGAGGTTCCG

Downstream 100 bases:

>100_bases
GGGACACCGTCGTCCGGGTGACCGGGGCCGCGCCGTACGACGTCGTCATCGGCCACGACCTGTCCGAGCGGCTGCCGCAG
CTGCTCGGGGTCGGGGTGCA

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTGPARPRVVLVGPMGAGKTTVARLLADAWGTGVRDTDHDVESAEGRTISDIFVDSGEGAFRDLERRAVAAALREHDGVL
ALGGGAVLDPGTRDLLAGHRVVFLRVGLSDAVKRVGLGVARPLLLGNVRGRIKALLDERTPIYESVATLVVDTDGRSPED
VAQEIRAALDGPALDGSALEGEA

Sequences:

>Translated_183_residues
MTGPARPRVVLVGPMGAGKTTVARLLADAWGTGVRDTDHDVESAEGRTISDIFVDSGEGAFRDLERRAVAAALREHDGVL
ALGGGAVLDPGTRDLLAGHRVVFLRVGLSDAVKRVGLGVARPLLLGNVRGRIKALLDERTPIYESVATLVVDTDGRSPED
VAQEIRAALDGPALDGSALEGEA
>Mature_182_residues
TGPARPRVVLVGPMGAGKTTVARLLADAWGTGVRDTDHDVESAEGRTISDIFVDSGEGAFRDLERRAVAAALREHDGVLA
LGGGAVLDPGTRDLLAGHRVVFLRVGLSDAVKRVGLGVARPLLLGNVRGRIKALLDERTPIYESVATLVVDTDGRSPEDV
AQEIRAALDGPALDGSALEGEA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=34.9397590361446, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786587, Length=174, Percent_Identity=32.7586206896552, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19064; Mature: 18933

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPARPRVVLVGPMGAGKTTVARLLADAWGTGVRDTDHDVESAEGRTISDIFVDSGEGA
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCEEEHEEEECCCHH
FRDLERRAVAAALREHDGVLALGGGAVLDPGTRDLLAGHRVVFLRVGLSDAVKRVGLGVA
HHHHHHHHHHHHHHHCCCEEEECCCEEECCCCHHHHCCCEEEEEEECHHHHHHHHCCHHH
RPLLLGNVRGRIKALLDERTPIYESVATLVVDTDGRSPEDVAQEIRAALDGPALDGSALE
HHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCC
GEA
CCC
>Mature Secondary Structure 
TGPARPRVVLVGPMGAGKTTVARLLADAWGTGVRDTDHDVESAEGRTISDIFVDSGEGA
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCEEEHEEEECCCHH
FRDLERRAVAAALREHDGVLALGGGAVLDPGTRDLLAGHRVVFLRVGLSDAVKRVGLGVA
HHHHHHHHHHHHHHHCCCEEEECCCEEECCCCHHHHCCCEEEEEEECHHHHHHHHCCHHH
RPLLLGNVRGRIKALLDERTPIYESVATLVVDTDGRSPEDVAQEIRAALDGPALDGSALE
HHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCC
GEA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]