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The map label for this gene is aroE [H]

Identifier: 119716637

GI number: 119716637

Start: 2570706

End: 2571518

Strand: Direct

Name: aroE [H]

Synonym: Noca_2410

Alternate gene names: 119716637

Gene position: 2570706-2571518 (Clockwise)

Preceding gene: 119716636

Following gene: 119716638

Centisome position: 51.56

GC content: 78.23

Gene sequence:

>813_bases
ATGACGCGCTGCGCCGTCCTCGGCGACCCGATCGCGCACTCGCTGTCGCCGGTCCTGCACCGGGCCGGGTACGCCGCGCT
CGGGCTGGACTGGAGCTACGAGGCCGTGCGGGTGCCGGAGGACGGGCTCGAGGGCTTCCTGACCGGCCTCGGCCCGCAGT
GGCGCGGGCTGTCGCTGACCATGCCGCTCAAGCGGCGCGCGCTGGCGATCGTGGCGGGCGTGACCGAGCGTGCTCGGCTG
GCCGGCGGGGTCAACACGCTGGTCCTCGAGGACGGCGCGGTCGTCCTGGCCGACAACACCGACCTGCCGGGGGCGGTGGC
CGCCGTGCGGGAGCGGTACGCCGGGCCGGTGACCGCGGGTACCGTCCTCGGGGGCGGTGCGACGGCCGCCGCCACCGGCC
TCGCGCTGGTCGAGCTCGGCGCCCGGCGGGTGCGCCTGCTCGCCCGCACGCCCGAACGCGCGGCGGCGGCCGCCGGGGCG
ATCGCGGCCCACCCGGCGGCCCCCCAGGTCGAGGTCGCGACGCTCGCGGACGGCCCGGTGGACGGCGAGATCGTGGTCTC
GACGATCCCGGCGGCCGCCCAGGACCCCTCGCTGGTCGCGCGCTGCGGCGCGGTCCCGGTGGTGTTCGAGGTGGTCTACG
ACCCCTGGCCGACCCCGCTCGCCGCGTCCGCCACCGGCCGGATCCTCGTCGGCGGCCTGGACCTGCTGGTGCACCAGGCG
GTCCTGCAGTTCGAGCTCTTCACCGGGGCACCCGGCCCCCTGGACGCCATGCGAGCAGCGGGGGAGCGGGCGCTCGGGAC
GGCGCCGGCGTGA

Upstream 100 bases:

>100_bases
CAGGAGTTCCTGGGCTTCAAGCAGGAGCTCCAGGAGTACTGCGACACCCAGTCCGACCGGTGCTGAGTCCCCGGGACCGG
CGGGGTCGGCAGGGTCGGCG

Downstream 100 bases:

>100_bases
GCGTCGACCCCGGTGCCGTCGTGCTGGGCGCCGCTGCCTGCGGCGCGGCCGGCCTGCTGGTGCCGGCCCTGATCGCGCGG
ATCCCCGAGCCGGATGCGGA

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTRCAVLGDPIAHSLSPVLHRAGYAALGLDWSYEAVRVPEDGLEGFLTGLGPQWRGLSLTMPLKRRALAIVAGVTERARL
AGGVNTLVLEDGAVVLADNTDLPGAVAAVRERYAGPVTAGTVLGGGATAAATGLALVELGARRVRLLARTPERAAAAAGA
IAAHPAAPQVEVATLADGPVDGEIVVSTIPAAAQDPSLVARCGAVPVVFEVVYDPWPTPLAASATGRILVGGLDLLVHQA
VLQFELFTGAPGPLDAMRAAGERALGTAPA

Sequences:

>Translated_270_residues
MTRCAVLGDPIAHSLSPVLHRAGYAALGLDWSYEAVRVPEDGLEGFLTGLGPQWRGLSLTMPLKRRALAIVAGVTERARL
AGGVNTLVLEDGAVVLADNTDLPGAVAAVRERYAGPVTAGTVLGGGATAAATGLALVELGARRVRLLARTPERAAAAAGA
IAAHPAAPQVEVATLADGPVDGEIVVSTIPAAAQDPSLVARCGAVPVVFEVVYDPWPTPLAASATGRILVGGLDLLVHQA
VLQFELFTGAPGPLDAMRAAGERALGTAPA
>Mature_269_residues
TRCAVLGDPIAHSLSPVLHRAGYAALGLDWSYEAVRVPEDGLEGFLTGLGPQWRGLSLTMPLKRRALAIVAGVTERARLA
GGVNTLVLEDGAVVLADNTDLPGAVAAVRERYAGPVTAGTVLGGGATAAATGLALVELGARRVRLLARTPERAAAAAGAI
AAHPAAPQVEVATLADGPVDGEIVVSTIPAAAQDPSLVARCGAVPVVFEVVYDPWPTPLAASATGRILVGGLDLLVHQAV
LQFELFTGAPGPLDAMRAAGERALGTAPA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=270, Percent_Identity=30, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789675, Length=262, Percent_Identity=31.2977099236641, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320332, Length=273, Percent_Identity=30.4029304029304, Blast_Score=99, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 27298; Mature: 27167

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRCAVLGDPIAHSLSPVLHRAGYAALGLDWSYEAVRVPEDGLEGFLTGLGPQWRGLSLT
CCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEECCHHHHHHHHHCCCCCCCCEEEE
MPLKRRALAIVAGVTERARLAGGVNTLVLEDGAVVLADNTDLPGAVAAVRERYAGPVTAG
CCHHHHHHHHHHCCHHHHHHHCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHCCCCCCC
TVLGGGATAAATGLALVELGARRVRLLARTPERAAAAAGAIAAHPAAPQVEVATLADGPV
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCCCCEEEEEECCCCC
DGEIVVSTIPAAAQDPSLVARCGAVPVVFEVVYDPWPTPLAASATGRILVGGLDLLVHQA
CCEEEEEECCCCCCCCHHHHHHCCCCEEEEEHHCCCCCCCCCCCCCEEEECHHHHHHHHH
VLQFELFTGAPGPLDAMRAAGERALGTAPA
HHHHHEECCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TRCAVLGDPIAHSLSPVLHRAGYAALGLDWSYEAVRVPEDGLEGFLTGLGPQWRGLSLT
CCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEECCHHHHHHHHHCCCCCCCCEEEE
MPLKRRALAIVAGVTERARLAGGVNTLVLEDGAVVLADNTDLPGAVAAVRERYAGPVTAG
CCHHHHHHHHHHCCHHHHHHHCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHCCCCCCC
TVLGGGATAAATGLALVELGARRVRLLARTPERAAAAAGAIAAHPAAPQVEVATLADGPV
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCCCCEEEEEECCCCC
DGEIVVSTIPAAAQDPSLVARCGAVPVVFEVVYDPWPTPLAASATGRILVGGLDLLVHQA
CCEEEEEECCCCCCCCHHHHHHCCCCEEEEEHHCCCCCCCCCCCCCEEEECHHHHHHHHH
VLQFELFTGAPGPLDAMRAAGERALGTAPA
HHHHHEECCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA