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The map label for this gene is aspS

Identifier: 119716625

GI number: 119716625

Start: 2555742

End: 2557514

Strand: Direct

Name: aspS

Synonym: Noca_2398

Alternate gene names: 119716625

Gene position: 2555742-2557514 (Clockwise)

Preceding gene: 119716624

Following gene: 119716626

Centisome position: 51.26

GC content: 70.28

Gene sequence:

>1773_bases
GTGATTCGCACCCAGGACGCCGGCGCACTGCGCGCCGAGAACGTCGGCCAGACCGTGACTCTCGCGGGGTGGGTGGCCAA
CCGGCGCGATCACGGTGGGGTCGCCTTCATCGACCTCCGCGAGGCCAGTGGGGTCGTCCAGGTCGTGATCCGCGACGAGC
AGGTCGCCCACCACCTGCGCGCGGAGTACTGCCTCGCGGTCACCGGCGAGGTCACCCGTCGCAAGGAGGGCAACGAGAAC
CCCAACCTGGCCACCGGCGAGGTCGAGGTCGTCGCGAACGAGGTCGAGGTGCTCAGCGCGGCCGCGCCGCTGCCGTTCCC
GATCAGCGACCACGTCGACGTGGGGGAGGAGGCCCGGCTCAAGCACCGGTACCTCGACCTGCGCCGCTCCGGGCCCAACA
ACGCGCTGCGCCTGCGCAGCAAGGTCAACAAGGCCGCCCGCGACGTGCTCGATCGTCACGACTTCGTCGAGATCGAGACT
CCCACGCTGACCCGGTCCACACCCGAGGGCGCGCGTGACTTCCTGGTGCCCGCCCGCCTCCAGCCCGGCAGCTGGTACGC
CCTGCCCCAGAGCCCACAGCTGTTCAAGCAGCTGCTGATGGTCGCCGGCATGGAGCGCTACTACCAGATCGCGCGGTGCT
ACCGCGACGAGGACTTCCGCGCCGACCGTCAGCCCGAGTTCACCCAGCTCGACATCGAGATGAGCTTCGTCGAGCAGGAC
GACGTGCTCGCGGTGGCCGAGGAGGTCCTCGTCGCGCTGTGGAAGCTGGTCGGGCACGACGTACCCGTCCCGCTGCCACG
GATGACCTACGCCGAGTCGATGGAGCGCTACGGGACCGACAAGCCGGACCTGCGGATGGGCCAGGAGCTGGTCGACTGCA
CCGCGTACTTCGCCGACACGCCGTTCCGCGTCTTCCAGGCCGACTACGTCGGTGCGGTCGTGATGCCCGGTGGCGCGAGC
CAGCCGCGCAAGCAGCTGGACGCCTGGCAGGAGTGGGCCAAGCAGCGGGGCGCCAAGGGTCTGGCCTACGTCCTGGTGCA
GGACGACGGGGAGCTCACCGGTCCGGTGTCGAAGAACATCACGGACGGGGAGTCGGCTGGCCTGGCCGAGCACACCGGGG
CGAAGCCCGGTGACTGCATCTTCTTCGCAGCGGGCGCGCCGAAGCCCAGTCGCGCACTGCTCGGCGCCGCGCGCCTCGAG
ATCGGCCGGCGGTGCGACCTGATCGACGAGGACGCCTGGAGCTTCCTGTGGGTCGTCGACGCGCCGCTGTTCGAGCCCAC
GGCCGACGCCACCGCCTCCGGCGACGTCGCCCTGGGCTACAGCGCCTGGACCGCCGTGCACCACGCGTTCACCTCGCCAC
AGGACGTCGACGGCTTCGACGCCGACCCCGGCAGCGCGCTCGCGTGGGCCTACGACATCGTCTGCAACGGCAACGAGATC
GGTGGCGGGTCGATCCGTATCCACCGCGAGGACGTCCAGAAGCGGGTCTTCGCGATCATGGGGATCGACGAGGCCGAGGC
GCAGGAGAAGTTCGGCTTCCTGCTCGAGGCGTTCAAGTACGGCGCCCCGCCGCACGGAGGGATCGCGTTCGGGTGGGACC
GCATCGTCGCGCTGCTCGCCGGCACCGAGTCGATCCGTGATGTGATCGCGTTCCCCAAGTCCGGTGGGGGTTTCGACCCG
CTCACTGCAGCTCCTGCGCCGATCACGCCCGAGCAGCGCAAGGAGGCGGGCGTGGACGCCCGACCTCAGCAGGACCTCCC
GCCGCAAAGCTGA

Upstream 100 bases:

>100_bases
AGCAGGTGGCGGCCGACCCCGCCTCCTGGACCCCACCCATCGAGGACCTGCGACCGCAGGTCGTTGCGACGAGCCCGACA
AGCGAGATGGAGAGTACGAA

Downstream 100 bases:

>100_bases
TCCGACGGACGTGGGGGCGAACGTCCCGAGACCAGATCGTTACACGCGGTAGACCCATTGATGTGCTGGCGTCACATAGA
GTCGCACCGGTCGCCGGCCC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MIRTQDAGALRAENVGQTVTLAGWVANRRDHGGVAFIDLREASGVVQVVIRDEQVAHHLRAEYCLAVTGEVTRRKEGNEN
PNLATGEVEVVANEVEVLSAAAPLPFPISDHVDVGEEARLKHRYLDLRRSGPNNALRLRSKVNKAARDVLDRHDFVEIET
PTLTRSTPEGARDFLVPARLQPGSWYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVEQD
DVLAVAEEVLVALWKLVGHDVPVPLPRMTYAESMERYGTDKPDLRMGQELVDCTAYFADTPFRVFQADYVGAVVMPGGAS
QPRKQLDAWQEWAKQRGAKGLAYVLVQDDGELTGPVSKNITDGESAGLAEHTGAKPGDCIFFAAGAPKPSRALLGAARLE
IGRRCDLIDEDAWSFLWVVDAPLFEPTADATASGDVALGYSAWTAVHHAFTSPQDVDGFDADPGSALAWAYDIVCNGNEI
GGGSIRIHREDVQKRVFAIMGIDEAEAQEKFGFLLEAFKYGAPPHGGIAFGWDRIVALLAGTESIRDVIAFPKSGGGFDP
LTAAPAPITPEQRKEAGVDARPQQDLPPQS

Sequences:

>Translated_590_residues
MIRTQDAGALRAENVGQTVTLAGWVANRRDHGGVAFIDLREASGVVQVVIRDEQVAHHLRAEYCLAVTGEVTRRKEGNEN
PNLATGEVEVVANEVEVLSAAAPLPFPISDHVDVGEEARLKHRYLDLRRSGPNNALRLRSKVNKAARDVLDRHDFVEIET
PTLTRSTPEGARDFLVPARLQPGSWYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVEQD
DVLAVAEEVLVALWKLVGHDVPVPLPRMTYAESMERYGTDKPDLRMGQELVDCTAYFADTPFRVFQADYVGAVVMPGGAS
QPRKQLDAWQEWAKQRGAKGLAYVLVQDDGELTGPVSKNITDGESAGLAEHTGAKPGDCIFFAAGAPKPSRALLGAARLE
IGRRCDLIDEDAWSFLWVVDAPLFEPTADATASGDVALGYSAWTAVHHAFTSPQDVDGFDADPGSALAWAYDIVCNGNEI
GGGSIRIHREDVQKRVFAIMGIDEAEAQEKFGFLLEAFKYGAPPHGGIAFGWDRIVALLAGTESIRDVIAFPKSGGGFDP
LTAAPAPITPEQRKEAGVDARPQQDLPPQS
>Mature_590_residues
MIRTQDAGALRAENVGQTVTLAGWVANRRDHGGVAFIDLREASGVVQVVIRDEQVAHHLRAEYCLAVTGEVTRRKEGNEN
PNLATGEVEVVANEVEVLSAAAPLPFPISDHVDVGEEARLKHRYLDLRRSGPNNALRLRSKVNKAARDVLDRHDFVEIET
PTLTRSTPEGARDFLVPARLQPGSWYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVEQD
DVLAVAEEVLVALWKLVGHDVPVPLPRMTYAESMERYGTDKPDLRMGQELVDCTAYFADTPFRVFQADYVGAVVMPGGAS
QPRKQLDAWQEWAKQRGAKGLAYVLVQDDGELTGPVSKNITDGESAGLAEHTGAKPGDCIFFAAGAPKPSRALLGAARLE
IGRRCDLIDEDAWSFLWVVDAPLFEPTADATASGDVALGYSAWTAVHHAFTSPQDVDGFDADPGSALAWAYDIVCNGNEI
GGGSIRIHREDVQKRVFAIMGIDEAEAQEKFGFLLEAFKYGAPPHGGIAFGWDRIVALLAGTESIRDVIAFPKSGGGFDP
LTAAPAPITPEQRKEAGVDARPQQDLPPQS

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=596, Percent_Identity=41.1073825503356, Blast_Score=433, Evalue=1e-121,
Organism=Homo sapiens, GI45439306, Length=278, Percent_Identity=27.6978417266187, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI194272210, Length=259, Percent_Identity=27.7992277992278, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI5031815, Length=259, Percent_Identity=27.7992277992278, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4758762, Length=242, Percent_Identity=27.6859504132231, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1788173, Length=595, Percent_Identity=47.0588235294118, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1789256, Length=296, Percent_Identity=26.0135135135135, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1790571, Length=289, Percent_Identity=26.643598615917, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566633, Length=608, Percent_Identity=33.3881578947368, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17551876, Length=274, Percent_Identity=27.7372262773723, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71994340, Length=251, Percent_Identity=25.4980079681275, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535925, Length=251, Percent_Identity=25.4980079681275, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17535927, Length=251, Percent_Identity=25.4980079681275, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325153, Length=624, Percent_Identity=33.0128205128205, Blast_Score=292, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6321807, Length=260, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=315, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324256, Length=190, Percent_Identity=24.2105263157895, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320242, Length=256, Percent_Identity=26.5625, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584738, Length=600, Percent_Identity=38.3333333333333, Blast_Score=359, Evalue=4e-99,
Organism=Drosophila melanogaster, GI17136276, Length=291, Percent_Identity=26.4604810996564, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640851, Length=259, Percent_Identity=25.8687258687259, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640849, Length=259, Percent_Identity=26.2548262548263, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922416, Length=325, Percent_Identity=24.9230769230769, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_NOCSJ (A1SJB8)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923590.1
- ProteinModelPortal:   A1SJB8
- SMR:   A1SJB8
- STRING:   A1SJB8
- GeneID:   4599498
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2398
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- PhylomeDB:   A1SJB8
- ProtClustDB:   PRK00476
- BioCyc:   NSP35761:NOCA_2398-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 64541; Mature: 64541

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTQDAGALRAENVGQTVTLAGWVANRRDHGGVAFIDLREASGVVQVVIRDEQVAHHLR
CCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHH
AEYCLAVTGEVTRRKEGNENPNLATGEVEVVANEVEVLSAAAPLPFPISDHVDVGEEARL
HHHEEEECCHHHHCCCCCCCCCEECCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
KHRYLDLRRSGPNNALRLRSKVNKAARDVLDRHDFVEIETPTLTRSTPEGARDFLVPARL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHCCCCCEE
QPGSWYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVEQD
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCC
DVLAVAEEVLVALWKLVGHDVPVPLPRMTYAESMERYGTDKPDLRMGQELVDCTAYFADT
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
PFRVFQADYVGAVVMPGGASQPRKQLDAWQEWAKQRGAKGLAYVLVQDDGELTGPVSKNI
CHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCC
TDGESAGLAEHTGAKPGDCIFFAAGAPKPSRALLGAARLEIGRRCDLIDEDAWSFLWVVD
CCCCCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
APLFEPTADATASGDVALGYSAWTAVHHAFTSPQDVDGFDADPGSALAWAYDIVCNGNEI
CCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCEE
GGGSIRIHREDVQKRVFAIMGIDEAEAQEKFGFLLEAFKYGAPPHGGIAFGWDRIVALLA
CCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHH
GTESIRDVIAFPKSGGGFDPLTAAPAPITPEQRKEAGVDARPQQDLPPQS
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRTQDAGALRAENVGQTVTLAGWVANRRDHGGVAFIDLREASGVVQVVIRDEQVAHHLR
CCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHH
AEYCLAVTGEVTRRKEGNENPNLATGEVEVVANEVEVLSAAAPLPFPISDHVDVGEEARL
HHHEEEECCHHHHCCCCCCCCCEECCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
KHRYLDLRRSGPNNALRLRSKVNKAARDVLDRHDFVEIETPTLTRSTPEGARDFLVPARL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHCCCCCEE
QPGSWYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVEQD
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCC
DVLAVAEEVLVALWKLVGHDVPVPLPRMTYAESMERYGTDKPDLRMGQELVDCTAYFADT
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
PFRVFQADYVGAVVMPGGASQPRKQLDAWQEWAKQRGAKGLAYVLVQDDGELTGPVSKNI
CHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCC
TDGESAGLAEHTGAKPGDCIFFAAGAPKPSRALLGAARLEIGRRCDLIDEDAWSFLWVVD
CCCCCCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
APLFEPTADATASGDVALGYSAWTAVHHAFTSPQDVDGFDADPGSALAWAYDIVCNGNEI
CCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCEE
GGGSIRIHREDVQKRVFAIMGIDEAEAQEKFGFLLEAFKYGAPPHGGIAFGWDRIVALLA
CCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHH
GTESIRDVIAFPKSGGGFDPLTAAPAPITPEQRKEAGVDARPQQDLPPQS
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA