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The map label for this gene is appC [H]

Identifier: 119716626

GI number: 119716626

Start: 2557678

End: 2558688

Strand: Direct

Name: appC [H]

Synonym: Noca_2399

Alternate gene names: 119716626

Gene position: 2557678-2558688 (Clockwise)

Preceding gene: 119716625

Following gene: 119716627

Centisome position: 51.3

GC content: 66.07

Gene sequence:

>1011_bases
ATGACTGTTCAGGCCTCCAACCTGGAGAGCGAACACCTGCCGGATCCCGCCGGTCCCCCGGAGGGTGAGACCAAGAAGAT
CGCCGGCAAGTCCCCGACGAAGCTGGCAATGGACCGGTTCCGCCGCGACAAGTTGTCCATGGTTTCCTTCACCGTCGTCG
CGATCTACATCGTCATCGGTGTGTCGGCGCCGTTCCTGGTGAAGTTCGGCGTGCTGGACCCGTTCAAGTTCCACCAGGAC
CTGCTGAACCCCGACACGCTGCCCAAGGGCCAGCTCGGTGGCATCAGCTGGGACCACCCGCTCGGCGTCGAGCCGGGCAC
CGGACGCGACGTGCTGTCCCGGCTGATCTACGGCGTCACGTTCTCGCTGACGATCGCGCTCTCGGCGACCGTCGTCGCGA
TCGCCATCGGCACCGTGCTCGGCATCATCTCCGGGTTCAGCGGGGGCTGGGTGGACGCGATCATCGGCCGCGCGGTCGAC
CTGACCCTGTCCTTCCCCCAGACGCTGATGCTGCTGGCCCTGTCGGGCATGGGCGTCGCGCTGGTCGCGGACTTCCTACC
GGGCAGCGAGTCCGACGACCTCCCGAACGGCTTCTACGTCGTCTTGGTGCTCGGCCTGTTCGGCTGGCCCGGCATCGCGC
GCATCATGCGCGGCCAGGTGCTCTCGGTCCGCGAGCGCGAGTTCGTCGACGCGGCCGTGCTGATCGGAGCGTCGCGACGC
CGGATCTACTTCAAGGAGATCCTGCCGAACCTGTGGGCGCCGCTGCTCGTCACGTTCACGTTGACGATGCCGGCCTACAT
CTCGGCGGAGGCTGCCTTGAGCTACCTGAGCGTCGGGATCCATCCGCCGACACCGACACTCGGCAACATCCTGCGCGGGT
CGATCAACTACTCGATCGGCGACTTCATGTTCTTCTTCGCGCCCGCCTTCGTGATCATGGTGATCGTCGTGAGCTTCAAC
CTGCTCGGTGACGGCATCCGTGACGCGCTCGACCCCAAGTCGGCCCGTTGA

Upstream 100 bases:

>100_bases
TGCTGGCGTCACATAGAGTCGCACCGGTCGCCGGCCCTCCGGTGCCCGTGATCCGGGCTCTGGAACCGACGGACAGCACA
CCCGAGAAGACAGAGGTGAC

Downstream 100 bases:

>100_bases
GCCCCGACCACGGGGACCCCCATTCTTCGGCGGCACGGAGCCGCCGAATGTGCCGCCGCTCCAGGCGCGACACACACCCA
AGGAGAAGTTAATGGTCAAG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTVQASNLESEHLPDPAGPPEGETKKIAGKSPTKLAMDRFRRDKLSMVSFTVVAIYIVIGVSAPFLVKFGVLDPFKFHQD
LLNPDTLPKGQLGGISWDHPLGVEPGTGRDVLSRLIYGVTFSLTIALSATVVAIAIGTVLGIISGFSGGWVDAIIGRAVD
LTLSFPQTLMLLALSGMGVALVADFLPGSESDDLPNGFYVVLVLGLFGWPGIARIMRGQVLSVREREFVDAAVLIGASRR
RIYFKEILPNLWAPLLVTFTLTMPAYISAEAALSYLSVGIHPPTPTLGNILRGSINYSIGDFMFFFAPAFVIMVIVVSFN
LLGDGIRDALDPKSAR

Sequences:

>Translated_336_residues
MTVQASNLESEHLPDPAGPPEGETKKIAGKSPTKLAMDRFRRDKLSMVSFTVVAIYIVIGVSAPFLVKFGVLDPFKFHQD
LLNPDTLPKGQLGGISWDHPLGVEPGTGRDVLSRLIYGVTFSLTIALSATVVAIAIGTVLGIISGFSGGWVDAIIGRAVD
LTLSFPQTLMLLALSGMGVALVADFLPGSESDDLPNGFYVVLVLGLFGWPGIARIMRGQVLSVREREFVDAAVLIGASRR
RIYFKEILPNLWAPLLVTFTLTMPAYISAEAALSYLSVGIHPPTPTLGNILRGSINYSIGDFMFFFAPAFVIMVIVVSFN
LLGDGIRDALDPKSAR
>Mature_335_residues
TVQASNLESEHLPDPAGPPEGETKKIAGKSPTKLAMDRFRRDKLSMVSFTVVAIYIVIGVSAPFLVKFGVLDPFKFHQDL
LNPDTLPKGQLGGISWDHPLGVEPGTGRDVLSRLIYGVTFSLTIALSATVVAIAIGTVLGIISGFSGGWVDAIIGRAVDL
TLSFPQTLMLLALSGMGVALVADFLPGSESDDLPNGFYVVLVLGLFGWPGIARIMRGQVLSVREREFVDAAVLIGASRRR
IYFKEILPNLWAPLLVTFTLTMPAYISAEAALSYLSVGIHPPTPTLGNILRGSINYSIGDFMFFFAPAFVIMVIVVSFNL
LGDGIRDALDPKSAR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=308, Percent_Identity=32.4675324675325, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789964, Length=314, Percent_Identity=34.3949044585987, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787760, Length=237, Percent_Identity=33.7552742616034, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787498, Length=312, Percent_Identity=30.4487179487179, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789889, Length=236, Percent_Identity=30.0847457627119, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788505, Length=231, Percent_Identity=26.4069264069264, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787549, Length=297, Percent_Identity=29.2929292929293, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36079; Mature: 35948

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQASNLESEHLPDPAGPPEGETKKIAGKSPTKLAMDRFRRDKLSMVSFTVVAIYIVIG
CCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSAPFLVKFGVLDPFKFHQDLLNPDTLPKGQLGGISWDHPLGVEPGTGRDVLSRLIYGVT
CCCHHHHEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FSLTIALSATVVAIAIGTVLGIISGFSGGWVDAIIGRAVDLTLSFPQTLMLLALSGMGVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEECCHHHHHHHHHCCCCHH
LVADFLPGSESDDLPNGFYVVLVLGLFGWPGIARIMRGQVLSVREREFVDAAVLIGASRR
HHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
RIYFKEILPNLWAPLLVTFTLTMPAYISAEAALSYLSVGIHPPTPTLGNILRGSINYSIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHH
DFMFFFAPAFVIMVIVVSFNLLGDGIRDALDPKSAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVQASNLESEHLPDPAGPPEGETKKIAGKSPTKLAMDRFRRDKLSMVSFTVVAIYIVIG
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSAPFLVKFGVLDPFKFHQDLLNPDTLPKGQLGGISWDHPLGVEPGTGRDVLSRLIYGVT
CCCHHHHEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FSLTIALSATVVAIAIGTVLGIISGFSGGWVDAIIGRAVDLTLSFPQTLMLLALSGMGVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEECCHHHHHHHHHCCCCHH
LVADFLPGSESDDLPNGFYVVLVLGLFGWPGIARIMRGQVLSVREREFVDAAVLIGASRR
HHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
RIYFKEILPNLWAPLLVTFTLTMPAYISAEAALSYLSVGIHPPTPTLGNILRGSINYSIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHH
DFMFFFAPAFVIMVIVVSFNLLGDGIRDALDPKSAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]