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The map label for this gene is ruvB

Identifier: 119716614

GI number: 119716614

Start: 2541965

End: 2543047

Strand: Direct

Name: ruvB

Synonym: Noca_2387

Alternate gene names: 119716614

Gene position: 2541965-2543047 (Clockwise)

Preceding gene: 119716613

Following gene: 119716615

Centisome position: 50.98

GC content: 72.48

Gene sequence:

>1083_bases
ATGACGTTCCACGAGGAGGACCTCGACCAGGCCGAGGAGGTGCACGTCCGCTCGCTCACCGCTGCTGAGGCGGACGGCGA
CGAGCGGGCCGTCGAGGCGGCGCTGCGGCCGCGCACCCTCGACGAGGTGGTCGGCCAGGTCCGGGTGCGCGACCAGCTCG
GGCTGGTGCTCGAGGCCGCACGCCGGCGTGGCCGGGCTCCCGACCACGTGCTGCTCTCCGGCCCGCCGGGTCTCGGCAAG
ACCACGCTGGCGATGATCATCGCCAGCGAGATGGGTGCGCCGCTGCGGCTGACCAGCGGTCCGGCGATCACGCATGCCGG
CGACCTGGCCGCGATCCTCTCCGGCATGAACGAGGGTGACGTCCTCTTCGTCGATGAGATCCACCGGATGTCGCGGCCGG
CCGAGGAGATGCTCTACATGGCGATGGAGGACTTCCGGGTCGACGTCGTCATCGGGAAGGGCCCCGGCGCCACCGCGATC
CCGTTGGAGATCCCGCCCTTCACCCTGGTCGGGGCGACCACCCGGGCAGGGCTGCTGCCCGGCCCGCTTCGAGACCGGTT
CGGCTTCACCGCCCACCTGGAGTTCTACGAGCCCGATGAGCTGGACCTGATCGTGCAGCGCTCGGCCCGGCTGCTCGACG
TGCACGTCCTCCCGGACGGGACCGCCGAGATCGCCTCGCGCTCGCGCGGTACGCCGCGGATCGCCAACCGGCTGCTGCGC
CGGGTCCGCGACTTCGCCCAAGTCCGCGCGGACGGCGTGGTCACCTTGCCGGTCGCCCAGGACGCGCTCGACCTCTACGA
GGTCGACCAGCTCGGGCTCGACCGGCTGGACCGCGGCGTCCTGGACGTGCTGTGCCGGCGCTTCGGTGGCGGGCCGGTCG
GCATCTCCACCCTGGCCGTGGCGGTCGGTGAGGAGCGCGAGACCGTGGAGGAGGTCGCGGAGCCCTTCTTGGTCCGCAAC
GGCTTCTTGGCGCGGACCCCGCGGGGCCGGGTGGCCACCCCGGCCGCCTGGGAGCACCTCGGTCTCACGGCTCCTCCGAC
GCTGACACTTCCCGAGAGCGATCCGCCACTCTTCGAGGACTGA

Upstream 100 bases:

>100_bases
GAGAAGGCCGTGGCTGCCGTCGCCCCCGAGGCGGGCGACGTCCCGGACGTCGCCGCGCTCTTGCGGGCGGCCCTGCGGAC
GCTGAGCAAGGCCTGAGCCG

Downstream 100 bases:

>100_bases
CGCGCCGGGCCGCAGGGGGGCCCGGATTCGCGGCGCCGCCCGCCGGCCCGGTTATGCTTGCCCGTCGGCCGGTCCGGTCC
GGGTCGCGCACTCGGTGCGC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTFHEEDLDQAEEVHVRSLTAAEADGDERAVEAALRPRTLDEVVGQVRVRDQLGLVLEAARRRGRAPDHVLLSGPPGLGK
TTLAMIIASEMGAPLRLTSGPAITHAGDLAAILSGMNEGDVLFVDEIHRMSRPAEEMLYMAMEDFRVDVVIGKGPGATAI
PLEIPPFTLVGATTRAGLLPGPLRDRFGFTAHLEFYEPDELDLIVQRSARLLDVHVLPDGTAEIASRSRGTPRIANRLLR
RVRDFAQVRADGVVTLPVAQDALDLYEVDQLGLDRLDRGVLDVLCRRFGGGPVGISTLAVAVGEERETVEEVAEPFLVRN
GFLARTPRGRVATPAAWEHLGLTAPPTLTLPESDPPLFED

Sequences:

>Translated_360_residues
MTFHEEDLDQAEEVHVRSLTAAEADGDERAVEAALRPRTLDEVVGQVRVRDQLGLVLEAARRRGRAPDHVLLSGPPGLGK
TTLAMIIASEMGAPLRLTSGPAITHAGDLAAILSGMNEGDVLFVDEIHRMSRPAEEMLYMAMEDFRVDVVIGKGPGATAI
PLEIPPFTLVGATTRAGLLPGPLRDRFGFTAHLEFYEPDELDLIVQRSARLLDVHVLPDGTAEIASRSRGTPRIANRLLR
RVRDFAQVRADGVVTLPVAQDALDLYEVDQLGLDRLDRGVLDVLCRRFGGGPVGISTLAVAVGEERETVEEVAEPFLVRN
GFLARTPRGRVATPAAWEHLGLTAPPTLTLPESDPPLFED
>Mature_359_residues
TFHEEDLDQAEEVHVRSLTAAEADGDERAVEAALRPRTLDEVVGQVRVRDQLGLVLEAARRRGRAPDHVLLSGPPGLGKT
TLAMIIASEMGAPLRLTSGPAITHAGDLAAILSGMNEGDVLFVDEIHRMSRPAEEMLYMAMEDFRVDVVIGKGPGATAIP
LEIPPFTLVGATTRAGLLPGPLRDRFGFTAHLEFYEPDELDLIVQRSARLLDVHVLPDGTAEIASRSRGTPRIANRLLRR
VRDFAQVRADGVVTLPVAQDALDLYEVDQLGLDRLDRGVLDVLCRRFGGGPVGISTLAVAVGEERETVEEVAEPFLVRNG
FLARTPRGRVATPAAWEHLGLTAPPTLTLPESDPPLFED

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=318, Percent_Identity=56.2893081761006, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_NOCSJ (A1SJA7)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923579.1
- ProteinModelPortal:   A1SJA7
- SMR:   A1SJA7
- STRING:   A1SJA7
- GeneID:   4599487
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2387
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   NSP35761:NOCA_2387-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 39020; Mature: 38889

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFHEEDLDQAEEVHVRSLTAAEADGDERAVEAALRPRTLDEVVGQVRVRDQLGLVLEAA
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RRRGRAPDHVLLSGPPGLGKTTLAMIIASEMGAPLRLTSGPAITHAGDLAAILSGMNEGD
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCCCC
VLFVDEIHRMSRPAEEMLYMAMEDFRVDVVIGKGPGATAIPLEIPPFTLVGATTRAGLLP
EEEHHHHHHHCCCHHHHHHHHHHHCEEEEEEECCCCCEEEEEECCCEEEECCCHHCCCCC
GPLRDRFGFTAHLEFYEPDELDLIVQRSARLLDVHVLPDGTAEIASRSRGTPRIANRLLR
CCHHHHCCCEEEEEEECCCCHHHHHHCCCEEEEEEECCCCHHHHHHCCCCCHHHHHHHHH
RVRDFAQVRADGVVTLPVAQDALDLYEVDQLGLDRLDRGVLDVLCRRFGGGPVGISTLAV
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AVGEERETVEEVAEPFLVRNGFLARTPRGRVATPAAWEHLGLTAPPTLTLPESDPPLFED
HHCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
TFHEEDLDQAEEVHVRSLTAAEADGDERAVEAALRPRTLDEVVGQVRVRDQLGLVLEAA
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RRRGRAPDHVLLSGPPGLGKTTLAMIIASEMGAPLRLTSGPAITHAGDLAAILSGMNEGD
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCCCC
VLFVDEIHRMSRPAEEMLYMAMEDFRVDVVIGKGPGATAIPLEIPPFTLVGATTRAGLLP
EEEHHHHHHHCCCHHHHHHHHHHHCEEEEEEECCCCCEEEEEECCCEEEECCCHHCCCCC
GPLRDRFGFTAHLEFYEPDELDLIVQRSARLLDVHVLPDGTAEIASRSRGTPRIANRLLR
CCHHHHCCCEEEEEEECCCCHHHHHHCCCEEEEEEECCCCHHHHHHCCCCCHHHHHHHHH
RVRDFAQVRADGVVTLPVAQDALDLYEVDQLGLDRLDRGVLDVLCRRFGGGPVGISTLAV
HHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AVGEERETVEEVAEPFLVRNGFLARTPRGRVATPAAWEHLGLTAPPTLTLPESDPPLFED
HHCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA