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The map label for this gene is ruvA

Identifier: 119716613

GI number: 119716613

Start: 2541358

End: 2541960

Strand: Direct

Name: ruvA

Synonym: Noca_2386

Alternate gene names: 119716613

Gene position: 2541358-2541960 (Clockwise)

Preceding gene: 119716612

Following gene: 119716614

Centisome position: 50.97

GC content: 73.3

Gene sequence:

>603_bases
ATGATCGCGTTCGTGCGCGGCCAGGTGGCGGCCGTGACCCTGTCGAGCGCCGTGCTCGAGGTCGGCGGCGTCGGCCTCGA
CATCATGTGCACACCCGGCACGCTGGCCACCCTCCGGGTCGGTCAACAGGCCGCGCTCCCGACCAGCATGGTGGTCCGGG
AGGACTCCCTGACGCTCTTCGGGTTCGCCGACGAGGACGAGAAGCAGACCTTCGAGCTGTTGCAGACCGCCTCCGGCGTC
GGCCCGAAGCTCGCCCAGGCGATGCTCGCCGTGCTCTCCACCGACGACCTGCGCCTGGCCATCACCGGGGACGACGTCAA
GACCCTGACCCGGGTGCCGGGCATCGGCCAGAAGGGCGCCCAGCGGATCATCCTGGAGCTCAGGGACCGGATCGGGGCAC
CCACCGGTGCCGGGCGCTCGGCCGGCGTTCCGGCGCCGGCAGGAGCCGTCTGGCGAGACCAGGTCCATCAGGGCCTGGTG
GGCCTGGGCTGGCCGGTCCGCGACGCCGAGAAGGCCGTGGCTGCCGTCGCCCCCGAGGCGGGCGACGTCCCGGACGTCGC
CGCGCTCTTGCGGGCGGCCCTGCGGACGCTGAGCAAGGCCTGA

Upstream 100 bases:

>100_bases
ACGCGCTGGCACTGGCCATCACCCACATCTGGCGCGGTGGCGCCCAGGCCCGGATCGACGCCGCGGTGACCGCAGCCCGA
CAGCAAGTGAGGAGCAGACG

Downstream 100 bases:

>100_bases
GCCGATGACGTTCCACGAGGAGGACCTCGACCAGGCCGAGGAGGTGCACGTCCGCTCGCTCACCGCTGCTGAGGCGGACG
GCGACGAGCGGGCCGTCGAG

Product: Holliday junction DNA helicase subunit RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MIAFVRGQVAAVTLSSAVLEVGGVGLDIMCTPGTLATLRVGQQAALPTSMVVREDSLTLFGFADEDEKQTFELLQTASGV
GPKLAQAMLAVLSTDDLRLAITGDDVKTLTRVPGIGQKGAQRIILELRDRIGAPTGAGRSAGVPAPAGAVWRDQVHQGLV
GLGWPVRDAEKAVAAVAPEAGDVPDVAALLRAALRTLSKA

Sequences:

>Translated_200_residues
MIAFVRGQVAAVTLSSAVLEVGGVGLDIMCTPGTLATLRVGQQAALPTSMVVREDSLTLFGFADEDEKQTFELLQTASGV
GPKLAQAMLAVLSTDDLRLAITGDDVKTLTRVPGIGQKGAQRIILELRDRIGAPTGAGRSAGVPAPAGAVWRDQVHQGLV
GLGWPVRDAEKAVAAVAPEAGDVPDVAALLRAALRTLSKA
>Mature_200_residues
MIAFVRGQVAAVTLSSAVLEVGGVGLDIMCTPGTLATLRVGQQAALPTSMVVREDSLTLFGFADEDEKQTFELLQTASGV
GPKLAQAMLAVLSTDDLRLAITGDDVKTLTRVPGIGQKGAQRIILELRDRIGAPTGAGRSAGVPAPAGAVWRDQVHQGLV
GLGWPVRDAEKAVAAVAPEAGDVPDVAALLRAALRTLSKA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=33.4975369458128, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_NOCSJ (A1SJA6)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923578.1
- ProteinModelPortal:   A1SJA6
- SMR:   A1SJA6
- STRING:   A1SJA6
- GeneID:   4599486
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2386
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   THLQVRE
- PhylomeDB:   A1SJA6
- ProtClustDB:   CLSK2783554
- BioCyc:   NSP35761:NOCA_2386-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20585; Mature: 20585

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAFVRGQVAAVTLSSAVLEVGGVGLDIMCTPGTLATLRVGQQAALPTSMVVREDSLTLF
CEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHCCCHHHEEECCCEEEE
GFADEDEKQTFELLQTASGVGPKLAQAMLAVLSTDDLRLAITGDDVKTLTRVPGIGQKGA
EECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCHHHH
QRIILELRDRIGAPTGAGRSAGVPAPAGAVWRDQVHQGLVGLGWPVRDAEKAVAAVAPEA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCC
GDVPDVAALLRAALRTLSKA
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAFVRGQVAAVTLSSAVLEVGGVGLDIMCTPGTLATLRVGQQAALPTSMVVREDSLTLF
CEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHCCCHHHEEECCCEEEE
GFADEDEKQTFELLQTASGVGPKLAQAMLAVLSTDDLRLAITGDDVKTLTRVPGIGQKGA
EECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCHHHH
QRIILELRDRIGAPTGAGRSAGVPAPAGAVWRDQVHQGLVGLGWPVRDAEKAVAAVAPEA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCC
GDVPDVAALLRAALRTLSKA
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA