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The map label for this gene is xylH [H]

Identifier: 119716605

GI number: 119716605

Start: 2533981

End: 2535240

Strand: Direct

Name: xylH [H]

Synonym: Noca_2378

Alternate gene names: 119716605

Gene position: 2533981-2535240 (Clockwise)

Preceding gene: 119716604

Following gene: 119716606

Centisome position: 50.82

GC content: 67.78

Gene sequence:

>1260_bases
ATGAGCGTCGCGACCGAAGAGATCCACGACCGCCAGGACACCCACAGCCGCGCCACCGTCGGCGGCCTGGTGAAGGAGTA
TCTGGCCAAGCTCCGAGGCGGCGACGTCGGCTCGCTTCCGGCGATCCTCGGACTCGTCGCGCTGGTCATCGTGTTCTCCA
GCCTGCGGCCCGAGACCTTTACCAAGGCGTTCAACTTCGGCAACCTGATCCAGCAGTCGGCGGGCGTCACGATCATCGCG
ATGGGGATGGTCTTCGTGCTGCTGCTCGGCGAGATCGACCTCTCGGCGGGCTACACGGGCGGCACGGCCGCCGCCGTGAT
GTCCCTCCTGCTCACCGAGCAGGGCTGGCCGACCCCCCTGGCGATCCTGGCCTGTCTCGCCACCGGCATGGTGATCGGCA
CCGGCATCGGCCTGATCGTCGCCTGGCTCGGCATCCCGTCGTTCGTCGTGACGCTGGCCATGTTCCTCGGCCTGCAGGGC
GTCATGCTCTCGATCATCGGCGAGAAGGGCTCGATCGACTCCGGCGAGTTCGTCGCGAAGCTCAACAGCGAGACCATCTC
GGTCTGGCTCGGATGGGTGATCGCGGTCGCCCTGGTCGGGCTCTACGCGACGTCGACGTTCCTGAGCAACCGGCGTCGGC
GGCGCCACGGCCTGACCAGCCAGCCGACGCTCCTCTGGGCACTGAAGTCGGGCGGCCTCGCCGTCATCACCATCCTGGTC
GTGTTCTACCTCTCGATCGAGCGCAGCCCGAACGCACACATCAAGTCGATCAAGGGCGTCCCGATCTCACTGCTCATCCT
GATCGGGCTCGCCCTCGTGCTCGGCGCACTGTTGAGCAGGACCAAGTGGGGCAGTCACGTCTACGCGGTCGGCGGCAACG
CCGAGGCGGCGCGCCGTGCCGGCATCAACGTCGCGATGATCAAGCTGAGCTGCTTCGTGCTGGGCTCCACGGTCGCGGCC
GTCGGCGGCATCATGCTCGCGAGCTACAGCGGCGGGGTGAACAACGTCACCGGAGGCAGCACGATCCTGCTGTACGCCGT
GGGCGCGGCCGTCATCGGCGGCACCAGTCTGTTCGGGGGCAAAGGACGCGTCATCGACGCCTTGATCGGCGGCACCGTCG
TGGCGGTGATCGCCAACGGCATGGGGCTGCTGAACCAGCCCGACAGCCGGAAGTACATCGTCACCGGCCTGGTGCTGCTC
GTGGCCGCCAGTGTCGACGCGATCAGTCGCAGGCGAGCGACCGCCACCGGACGGGCCTGA

Upstream 100 bases:

>100_bases
ACCTCGGCCAGATGGTCGGCCAGGTGGATGTCGCCACCACCAGCCGTGAGCGGGTCATCGCGGCGATCACGACCGGCAAG
GTGAACGAGGGGGATGCGGC

Downstream 100 bases:

>100_bases
TCTCGATGCCCACCCCCACCGGAGTCGGCACCGACGAGCTGCGGCGCGCGAATCTCCGCGCGATCCTGCAGACGGTGCAC
ACGCGCGGTCCGACGACCCG

Product: inner-membrane translocator

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSVATEEIHDRQDTHSRATVGGLVKEYLAKLRGGDVGSLPAILGLVALVIVFSSLRPETFTKAFNFGNLIQQSAGVTIIA
MGMVFVLLLGEIDLSAGYTGGTAAAVMSLLLTEQGWPTPLAILACLATGMVIGTGIGLIVAWLGIPSFVVTLAMFLGLQG
VMLSIIGEKGSIDSGEFVAKLNSETISVWLGWVIAVALVGLYATSTFLSNRRRRRHGLTSQPTLLWALKSGGLAVITILV
VFYLSIERSPNAHIKSIKGVPISLLILIGLALVLGALLSRTKWGSHVYAVGGNAEAARRAGINVAMIKLSCFVLGSTVAA
VGGIMLASYSGGVNNVTGGSTILLYAVGAAVIGGTSLFGGKGRVIDALIGGTVVAVIANGMGLLNQPDSRKYIVTGLVLL
VAASVDAISRRRATATGRA

Sequences:

>Translated_419_residues
MSVATEEIHDRQDTHSRATVGGLVKEYLAKLRGGDVGSLPAILGLVALVIVFSSLRPETFTKAFNFGNLIQQSAGVTIIA
MGMVFVLLLGEIDLSAGYTGGTAAAVMSLLLTEQGWPTPLAILACLATGMVIGTGIGLIVAWLGIPSFVVTLAMFLGLQG
VMLSIIGEKGSIDSGEFVAKLNSETISVWLGWVIAVALVGLYATSTFLSNRRRRRHGLTSQPTLLWALKSGGLAVITILV
VFYLSIERSPNAHIKSIKGVPISLLILIGLALVLGALLSRTKWGSHVYAVGGNAEAARRAGINVAMIKLSCFVLGSTVAA
VGGIMLASYSGGVNNVTGGSTILLYAVGAAVIGGTSLFGGKGRVIDALIGGTVVAVIANGMGLLNQPDSRKYIVTGLVLL
VAASVDAISRRRATATGRA
>Mature_418_residues
SVATEEIHDRQDTHSRATVGGLVKEYLAKLRGGDVGSLPAILGLVALVIVFSSLRPETFTKAFNFGNLIQQSAGVTIIAM
GMVFVLLLGEIDLSAGYTGGTAAAVMSLLLTEQGWPTPLAILACLATGMVIGTGIGLIVAWLGIPSFVVTLAMFLGLQGV
MLSIIGEKGSIDSGEFVAKLNSETISVWLGWVIAVALVGLYATSTFLSNRRRRRHGLTSQPTLLWALKSGGLAVITILVV
FYLSIERSPNAHIKSIKGVPISLLILIGLALVLGALLSRTKWGSHVYAVGGNAEAARRAGINVAMIKLSCFVLGSTVAAV
GGIMLASYSGGVNNVTGGSTILLYAVGAAVIGGTSLFGGKGRVIDALIGGTVVAVIANGMGLLNQPDSRKYIVTGLVLLV
AASVDAISRRRATATGRA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=373, Percent_Identity=33.2439678284182, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790524, Length=156, Percent_Identity=32.0512820512821, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788896, Length=160, Percent_Identity=35.625, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693152, Length=158, Percent_Identity=34.8101265822785, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790191, Length=149, Percent_Identity=38.255033557047, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 43240; Mature: 43109

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVATEEIHDRQDTHSRATVGGLVKEYLAKLRGGDVGSLPAILGLVALVIVFSSLRPETF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
TKAFNFGNLIQQSAGVTIIAMGMVFVLLLGEIDLSAGYTGGTAAAVMSLLLTEQGWPTPL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHH
AILACLATGMVIGTGIGLIVAWLGIPSFVVTLAMFLGLQGVMLSIIGEKGSIDSGEFVAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LNSETISVWLGWVIAVALVGLYATSTFLSNRRRRRHGLTSQPTLLWALKSGGLAVITILV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHH
VFYLSIERSPNAHIKSIKGVPISLLILIGLALVLGALLSRTKWGSHVYAVGGNAEAARRA
HHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHC
GINVAMIKLSCFVLGSTVAAVGGIMLASYSGGVNNVTGGSTILLYAVGAAVIGGTSLFGG
CCEEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEECC
KGRVIDALIGGTVVAVIANGMGLLNQPDSRKYIVTGLVLLVAASVDAISRRRATATGRA
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVATEEIHDRQDTHSRATVGGLVKEYLAKLRGGDVGSLPAILGLVALVIVFSSLRPETF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
TKAFNFGNLIQQSAGVTIIAMGMVFVLLLGEIDLSAGYTGGTAAAVMSLLLTEQGWPTPL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHH
AILACLATGMVIGTGIGLIVAWLGIPSFVVTLAMFLGLQGVMLSIIGEKGSIDSGEFVAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LNSETISVWLGWVIAVALVGLYATSTFLSNRRRRRHGLTSQPTLLWALKSGGLAVITILV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHH
VFYLSIERSPNAHIKSIKGVPISLLILIGLALVLGALLSRTKWGSHVYAVGGNAEAARRA
HHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHC
GINVAMIKLSCFVLGSTVAAVGGIMLASYSGGVNNVTGGSTILLYAVGAAVIGGTSLFGG
CCEEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEECC
KGRVIDALIGGTVVAVIANGMGLLNQPDSRKYIVTGLVLLVAASVDAISRRRATATGRA
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]