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The map label for this gene is xylR [H]

Identifier: 119716606

GI number: 119716606

Start: 2535246

End: 2536433

Strand: Direct

Name: xylR [H]

Synonym: Noca_2379

Alternate gene names: 119716606

Gene position: 2535246-2536433 (Clockwise)

Preceding gene: 119716605

Following gene: 119716607

Centisome position: 50.85

GC content: 74.33

Gene sequence:

>1188_bases
ATGCCCACCCCCACCGGAGTCGGCACCGACGAGCTGCGGCGCGCGAATCTCCGCGCGATCCTGCAGACGGTGCACACGCG
CGGTCCGACGACCCGCGCGGTCCTCACCCGCCAGCTCGGGCTCAACCGCAGCACGATCGGTGCGCTCACCGGCGAGCTGC
AGAGCCTCGGGCTGGTCTCGGAGGAGACCTCGGCGGTGGGTGGGCGCTCGGGACGTCCGTCGCACCTGGTGGTGCCGCGG
GAGGACAACGTCGTCGTCGCGGTCGACGTGGGGGTGGATCGGATCGCGGTGGCCCTCGTGGGTCTCGGCGGTGAGGTCCT
CGACCGGCGCGACCGTCGCCACCAGCGGGGCGAGCACGACGTCGCACATGTCGTCGACGCGGTCGCCCAGATGGTGGAGG
ACATCCTCGCCGGGGCCGGCCACCGGGTGCGGTGCCTCGGCGTCGGCGTCGCCGTACCGGGTGCGGTCCGGGCTGCCGAC
GGCTTCGTCCGGTTCGCGCCGAACCTCGGCTGGGTGGAGGAGCCGTTCACCGACCTGCTGGCCGCGCGGCTCGACCGGCC
GGTGGCCACGGGGAACGACGCCGACCTGGGCGCGCTCGCCGAGCACGTGCGGGGGGTCGCGATCGGCTACTCCGAGGCGG
TCTACCTCAGCGCCAGCGTCGGCATCGGCGGCGGCTTCCTGATGGCGGGCCGGCCACTGGCCGGCGCGCGCGGGTACGCC
GGCGAGGTCGGCCACATGCAGGTCGACAGCCAGGGCCCGGTCTGCCGGTGCGGTGCCGTCGGCTGCTGGGAGACCAAGGT
GGGGGAGAACGTGCTGCTGCGGCTTGCGGGCCGACTGCCCGGCGGCGGACCGCCCGCGATCGCCGAGGTCATCGAGGCGG
CCCGGGCGGGGGAGCAGCGCGCCGCAGACGCGGTCGCGGAGGTCGCGGAGTGGTGCGGTGTCGGCCTGCGCGGGATCGTC
AACCTGTTCGATCCCGAGATCGTGGTGCTCGGTGGCTGCCTGGCGCAGGTGTGGAAGGCAGCGGAGGCAACCGTCAACGA
GGCGATGGCGCGGAGCACGATGATGCCGCGCGACGACGTCTTGATCCGCGCCGCCCAGTTCGGTGTCGACTCCCCGCTGA
TCGGCGCCGCCGAGCTGGCCTTCGCGCCGGTGCTCGACCACCCCCAGGCCGTGCCAAACGCCAGCTGA

Upstream 100 bases:

>100_bases
GCCGGAAGTACATCGTCACCGGCCTGGTGCTGCTCGTGGCCGCCAGTGTCGACGCGATCAGTCGCAGGCGAGCGACCGCC
ACCGGACGGGCCTGATCTCG

Downstream 100 bases:

>100_bases
GGGGCTCCGGCCCGGTAGCCTGCTGCCGCCATGCTCGAACGTTTCCGCGCCTTCTGGACCAAGGTGATCTCGCCGATCGC
CCATCTGCTGATCCGGATGG

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MPTPTGVGTDELRRANLRAILQTVHTRGPTTRAVLTRQLGLNRSTIGALTGELQSLGLVSEETSAVGGRSGRPSHLVVPR
EDNVVVAVDVGVDRIAVALVGLGGEVLDRRDRRHQRGEHDVAHVVDAVAQMVEDILAGAGHRVRCLGVGVAVPGAVRAAD
GFVRFAPNLGWVEEPFTDLLAARLDRPVATGNDADLGALAEHVRGVAIGYSEAVYLSASVGIGGGFLMAGRPLAGARGYA
GEVGHMQVDSQGPVCRCGAVGCWETKVGENVLLRLAGRLPGGGPPAIAEVIEAARAGEQRAADAVAEVAEWCGVGLRGIV
NLFDPEIVVLGGCLAQVWKAAEATVNEAMARSTMMPRDDVLIRAAQFGVDSPLIGAAELAFAPVLDHPQAVPNAS

Sequences:

>Translated_395_residues
MPTPTGVGTDELRRANLRAILQTVHTRGPTTRAVLTRQLGLNRSTIGALTGELQSLGLVSEETSAVGGRSGRPSHLVVPR
EDNVVVAVDVGVDRIAVALVGLGGEVLDRRDRRHQRGEHDVAHVVDAVAQMVEDILAGAGHRVRCLGVGVAVPGAVRAAD
GFVRFAPNLGWVEEPFTDLLAARLDRPVATGNDADLGALAEHVRGVAIGYSEAVYLSASVGIGGGFLMAGRPLAGARGYA
GEVGHMQVDSQGPVCRCGAVGCWETKVGENVLLRLAGRLPGGGPPAIAEVIEAARAGEQRAADAVAEVAEWCGVGLRGIV
NLFDPEIVVLGGCLAQVWKAAEATVNEAMARSTMMPRDDVLIRAAQFGVDSPLIGAAELAFAPVLDHPQAVPNAS
>Mature_394_residues
PTPTGVGTDELRRANLRAILQTVHTRGPTTRAVLTRQLGLNRSTIGALTGELQSLGLVSEETSAVGGRSGRPSHLVVPRE
DNVVVAVDVGVDRIAVALVGLGGEVLDRRDRRHQRGEHDVAHVVDAVAQMVEDILAGAGHRVRCLGVGVAVPGAVRAADG
FVRFAPNLGWVEEPFTDLLAARLDRPVATGNDADLGALAEHVRGVAIGYSEAVYLSASVGIGGGFLMAGRPLAGARGYAG
EVGHMQVDSQGPVCRCGAVGCWETKVGENVLLRLAGRLPGGGPPAIAEVIEAARAGEQRAADAVAEVAEWCGVGLRGIVN
LFDPEIVVLGGCLAQVWKAAEATVNEAMARSTMMPRDDVLIRAAQFGVDSPLIGAAELAFAPVLDHPQAVPNAS

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI4885285, Length=269, Percent_Identity=28.2527881040892, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI190014632, Length=269, Percent_Identity=28.2527881040892, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI298566315, Length=269, Percent_Identity=28.2527881040892, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI298566325, Length=269, Percent_Identity=28.2527881040892, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786891, Length=359, Percent_Identity=25.0696378830084, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787878, Length=381, Percent_Identity=23.6220472440945, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081733, Length=305, Percent_Identity=28.5245901639344, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787363, Length=268, Percent_Identity=28.7313432835821, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790522, Length=258, Percent_Identity=28.6821705426357, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082230, Length=251, Percent_Identity=28.6852589641434, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 40926; Mature: 40795

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPTGVGTDELRRANLRAILQTVHTRGPTTRAVLTRQLGLNRSTIGALTGELQSLGLVS
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
EETSAVGGRSGRPSHLVVPREDNVVVAVDVGVDRIAVALVGLGGEVLDRRDRRHQRGEHD
HHHHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHCCCHH
VAHVVDAVAQMVEDILAGAGHRVRCLGVGVAVPGAVRAADGFVRFAPNLGWVEEPFTDLL
HHHHHHHHHHHHHHHHHCCCCEEEEEEECEECCCHHHHCCCCEEECCCCCCCCCHHHHHH
AARLDRPVATGNDADLGALAEHVRGVAIGYSEAVYLSASVGIGGGFLMAGRPLAGARGYA
HHHHCCCCCCCCCCCHHHHHHHHCCEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCCC
GEVGHMQVDSQGPVCRCGAVGCWETKVGENVLLRLAGRLPGGGPPAIAEVIEAARAGEQR
CCCCCEEECCCCCEEEECCCCCCHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHH
AADAVAEVAEWCGVGLRGIVNLFDPEIVVLGGCLAQVWKAAEATVNEAMARSTMMPRDDV
HHHHHHHHHHHHCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LIRAAQFGVDSPLIGAAELAFAPVLDHPQAVPNAS
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PTPTGVGTDELRRANLRAILQTVHTRGPTTRAVLTRQLGLNRSTIGALTGELQSLGLVS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
EETSAVGGRSGRPSHLVVPREDNVVVAVDVGVDRIAVALVGLGGEVLDRRDRRHQRGEHD
HHHHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHCCCHH
VAHVVDAVAQMVEDILAGAGHRVRCLGVGVAVPGAVRAADGFVRFAPNLGWVEEPFTDLL
HHHHHHHHHHHHHHHHHCCCCEEEEEEECEECCCHHHHCCCCEEECCCCCCCCCHHHHHH
AARLDRPVATGNDADLGALAEHVRGVAIGYSEAVYLSASVGIGGGFLMAGRPLAGARGYA
HHHHCCCCCCCCCCCHHHHHHHHCCEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCCC
GEVGHMQVDSQGPVCRCGAVGCWETKVGENVLLRLAGRLPGGGPPAIAEVIEAARAGEQR
CCCCCEEECCCCCEEEECCCCCCHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHH
AADAVAEVAEWCGVGLRGIVNLFDPEIVVLGGCLAQVWKAAEATVNEAMARSTMMPRDDV
HHHHHHHHHHHHCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LIRAAQFGVDSPLIGAAELAFAPVLDHPQAVPNAS
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]