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The map label for this gene is suhB [H]

Identifier: 119716600

GI number: 119716600

Start: 2528913

End: 2529692

Strand: Direct

Name: suhB [H]

Synonym: Noca_2373

Alternate gene names: 119716600

Gene position: 2528913-2529692 (Clockwise)

Preceding gene: 119716599

Following gene: 119716601

Centisome position: 50.72

GC content: 76.41

Gene sequence:

>780_bases
GTGAGCCCGGACCCGAGCCTGGCCGAGGACGCCGCCCTCGCCGCCCGCCTGGTCCGCGACGCCGGCACCCTGGCGGCCCG
GATGCGCGCCGAGGGGCTCGAGGCCGCGACCAAGACCTCGATCTCCGACGTCGTGACCGCTGCCGACCACGCCGCCGAGC
GACTCGTCGTCGACGCCCTCGCGGCCGAGCGACCCCGCGACGGCGTGCTGGGGGAGGAGGGCGCGGCGAGCGAGGGTACG
TCGGGCCGCACCTGGGTGATCGACCCGGTCGACGGCACCTACAACTTCGTGGCCGGCCTGGACTGGTGGTGCTCCGCGCT
CGCGCTGACCGATGGTGACGACCTCGTGCTCGGGGCCGTCCACCACCCGGCCTCCGGGCGGACCTTCGTCGGTGGGCCGG
GCCTCCCGACGACCGTGGACGGCGTCGCGTTGCCCGCCCTCGACGACCGCCGACTCGCCGCGGCCTGCCTGACGACCTAC
CTGCATCCGCCGTCGTACGGCGCGGAGGTCGGCGCGGCCTTCACCCGCCTGGTGGGCGGCGCGGCGACCCTGCGGATGCT
CGGTTCGGCGTCGATGGACGCCACCGCGATCGCGTCGGGTCAGCTGCACGTCCGGTGCCAGCACTCGTTGCCACCCTGGG
ACGACCTGCCCGGCGCCGCGCTGATCCTCGGGGTGGGCGGAGCGACCGCGCACGTGGACGCTGCAGGTGTGCGCTGGTCG
GCTGCGGGTGCGCCGCGCGCCGTGGCGGACGTCTGCGCCGCCCTGGAGGCGACCGGCTGA

Upstream 100 bases:

>100_bases
GCTGGTCCGGGGACGCCAACTTCATCACCGTGCTCGGCGGCACCAAGACGCTCCCGCAGCTGCTCGCGGACACGCGCCGC
CTGCTCGTCGAGGCCTGGGC

Downstream 100 bases:

>100_bases
GGTTGTTCGTTGCGGATCGGCTGACGGGGGAGGAGCGTGGTCACCGTCCGGCGACGCCATCCGGGCGCCGTCCCGAGGCG
GGAGGCACAGCCATGCACGC

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSPDPSLAEDAALAARLVRDAGTLAARMRAEGLEAATKTSISDVVTAADHAAERLVVDALAAERPRDGVLGEEGAASEGT
SGRTWVIDPVDGTYNFVAGLDWWCSALALTDGDDLVLGAVHHPASGRTFVGGPGLPTTVDGVALPALDDRRLAAACLTTY
LHPPSYGAEVGAAFTRLVGGAATLRMLGSASMDATAIASGQLHVRCQHSLPPWDDLPGAALILGVGGATAHVDAAGVRWS
AAGAPRAVADVCAALEATG

Sequences:

>Translated_259_residues
MSPDPSLAEDAALAARLVRDAGTLAARMRAEGLEAATKTSISDVVTAADHAAERLVVDALAAERPRDGVLGEEGAASEGT
SGRTWVIDPVDGTYNFVAGLDWWCSALALTDGDDLVLGAVHHPASGRTFVGGPGLPTTVDGVALPALDDRRLAAACLTTY
LHPPSYGAEVGAAFTRLVGGAATLRMLGSASMDATAIASGQLHVRCQHSLPPWDDLPGAALILGVGGATAHVDAAGVRWS
AAGAPRAVADVCAALEATG
>Mature_258_residues
SPDPSLAEDAALAARLVRDAGTLAARMRAEGLEAATKTSISDVVTAADHAAERLVVDALAAERPRDGVLGEEGAASEGTS
GRTWVIDPVDGTYNFVAGLDWWCSALALTDGDDLVLGAVHHPASGRTFVGGPGLPTTVDGVALPALDDRRLAAACLTTYL
HPPSYGAEVGAAFTRLVGGAATLRMLGSASMDATAIASGQLHVRCQHSLPPWDDLPGAALILGVGGATAHVDAAGVRWSA
AGAPRAVADVCAALEATG

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=231, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI5031789, Length=240, Percent_Identity=24.1666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221625487, Length=240, Percent_Identity=24.1666666666667, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788882, Length=256, Percent_Identity=28.515625, Blast_Score=88, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI193202570, Length=215, Percent_Identity=27.4418604651163, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193202572, Length=226, Percent_Identity=26.5486725663717, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357329, Length=268, Percent_Identity=27.2388059701493, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24664922, Length=270, Percent_Identity=24.8148148148148, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24664926, Length=232, Percent_Identity=27.1551724137931, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357303, Length=233, Percent_Identity=27.8969957081545, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24664918, Length=228, Percent_Identity=28.5087719298246, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21357957, Length=228, Percent_Identity=25.4385964912281, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 26105; Mature: 25974

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDPSLAEDAALAARLVRDAGTLAARMRAEGLEAATKTSISDVVTAADHAAERLVVDAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAERPRDGVLGEEGAASEGTSGRTWVIDPVDGTYNFVAGLDWWCSALALTDGDDLVLGAV
HHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHEECCCCCEEEEEE
HHPASGRTFVGGPGLPTTVDGVALPALDDRRLAAACLTTYLHPPSYGAEVGAAFTRLVGG
ECCCCCCEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AATLRMLGSASMDATAIASGQLHVRCQHSLPPWDDLPGAALILGVGGATAHVDAAGVRWS
HHHHHHHCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEECCCCEEE
AAGAPRAVADVCAALEATG
CCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPDPSLAEDAALAARLVRDAGTLAARMRAEGLEAATKTSISDVVTAADHAAERLVVDAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAERPRDGVLGEEGAASEGTSGRTWVIDPVDGTYNFVAGLDWWCSALALTDGDDLVLGAV
HHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHEECCCCCEEEEEE
HHPASGRTFVGGPGLPTTVDGVALPALDDRRLAAACLTTYLHPPSYGAEVGAAFTRLVGG
ECCCCCCEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AATLRMLGSASMDATAIASGQLHVRCQHSLPPWDDLPGAALILGVGGATAHVDAAGVRWS
HHHHHHHCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEECCCCEEE
AAGAPRAVADVCAALEATG
CCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]