The gene/protein map for NC_008699 is currently unavailable.
Definition Nocardioides sp. JS614 chromosome, complete genome.
Accession NC_008699
Length 4,985,871

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The map label for this gene is xylL [H]

Identifier: 119716367

GI number: 119716367

Start: 2285020

End: 2285844

Strand: Reverse

Name: xylL [H]

Synonym: Noca_2136

Alternate gene names: 119716367

Gene position: 2285844-2285020 (Counterclockwise)

Preceding gene: 119716368

Following gene: 119716366

Centisome position: 45.85

GC content: 63.88

Gene sequence:

>825_bases
ATGAGGCCTGAAGACGCCGACCTAGATGTTCGGGCCGGCAATCGACTGCGCGGCAAAACCGTCATCATCACCGGTGCCGG
GCGCGGGATCGGACGGGCAGCCGCCAGGCGCATGGCGACCGAAGGCGCCCAGCTCCTGCTCGCCGACCTCAATGCCGAAA
CGCTGGACCAGGTGATCCAAGAGACCTCCGAGATCACCACGTCGTCAGCCTTCACCGGCGACCTTATGCAGTACGCGACA
GCGGAGAAGTTGATCTCAACCTGTCTCGAGCGATACGGCCAGGTCGATGTCCTCGTGAACAACATCGGCGGTGCAACAGC
GCTCAAGCCGCTGTGGGACTGGAGCGACGAGGAGATCCTAGCGGAGATGAACCGCAGCATCCTTCCGACTGTTTGGTGTT
GCCGGGCCGTGCTGCCGACCATGATTGAACAGGGGCAGGGCCGGATCGTGAACGTCGGCGCGGAGTCCGTCCGAAACGGG
TTGTGGGATCGGGCGCCGTACAACATGGCCAAGGGAGCTGTCCACGCGCTCACGACGAGCATCGCTCGCGAGACGGCCGA
CAAGGGCATCCTCTGCAATTGTGTCGCGCCTGCGGCGACCGGACGCACCGACGGCCGGCTAGAGCGCCGAGTCGACCGTA
AGCGAAGCCCCGAAGAGCTCGCGCACATCGCGCGAATCAACGAAATGATGCTCGATTCGATTCCCTTGGGTCGCCCGGCC
TACCCCGAGGAGCAGGCGGCTGCGATCGCATTCCTTGCCTCTGACGACGCGTCGTTCATTACCGGCCAGGTTCTGAGCGT
CAACGGTGGGTCCTCGATGCTCTGA

Upstream 100 bases:

>100_bases
AGCTCATTCTCGAAAACGCACGCGACTTCCACCTCAAGGACGGTCACGACACCGAGTGGCCTGATGCTGCAGGCGCCACG
TCGGCCAAGGAGGACAGCAA

Downstream 100 bases:

>100_bases
AAGCAGTCGATCGCCTGCACCAATCCCATCTCAACGACTCAAAGCGGAGGACTCATGGCCCGCAACCTCGTGGCGCACAT
CTCTGACCTAACCCCAGGGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 2-hydro-1,2-dihydroxybenzoate dehydrogenase; DHB dehydrogenase; Cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase; Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MRPEDADLDVRAGNRLRGKTVIITGAGRGIGRAAARRMATEGAQLLLADLNAETLDQVIQETSEITTSSAFTGDLMQYAT
AEKLISTCLERYGQVDVLVNNIGGATALKPLWDWSDEEILAEMNRSILPTVWCCRAVLPTMIEQGQGRIVNVGAESVRNG
LWDRAPYNMAKGAVHALTTSIARETADKGILCNCVAPAATGRTDGRLERRVDRKRSPEELAHIARINEMMLDSIPLGRPA
YPEEQAAAIAFLASDDASFITGQVLSVNGGSSML

Sequences:

>Translated_274_residues
MRPEDADLDVRAGNRLRGKTVIITGAGRGIGRAAARRMATEGAQLLLADLNAETLDQVIQETSEITTSSAFTGDLMQYAT
AEKLISTCLERYGQVDVLVNNIGGATALKPLWDWSDEEILAEMNRSILPTVWCCRAVLPTMIEQGQGRIVNVGAESVRNG
LWDRAPYNMAKGAVHALTTSIARETADKGILCNCVAPAATGRTDGRLERRVDRKRSPEELAHIARINEMMLDSIPLGRPA
YPEEQAAAIAFLASDDASFITGQVLSVNGGSSML
>Mature_274_residues
MRPEDADLDVRAGNRLRGKTVIITGAGRGIGRAAARRMATEGAQLLLADLNAETLDQVIQETSEITTSSAFTGDLMQYAT
AEKLISTCLERYGQVDVLVNNIGGATALKPLWDWSDEEILAEMNRSILPTVWCCRAVLPTMIEQGQGRIVNVGAESVRNG
LWDRAPYNMAKGAVHALTTSIARETADKGILCNCVAPAATGRTDGRLERRVDRKRSPEELAHIARINEMMLDSIPLGRPA
YPEEQAAAIAFLASDDASFITGQVLSVNGGSSML

Specific function: Degradation of 2-hydro-1,2-dihydroxy benzoate (DHB) to catechol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=27.7992277992278, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=28.030303030303, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI66933014, Length=262, Percent_Identity=33.206106870229, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI15277342, Length=271, Percent_Identity=29.1512915129151, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI40254992, Length=256, Percent_Identity=28.515625, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI126723750, Length=267, Percent_Identity=25.0936329588015, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=28.515625, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI210032110, Length=185, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=30.2564102564103, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=271, Percent_Identity=27.3062730627306, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=29.9492385786802, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI59889578, Length=245, Percent_Identity=28.1632653061224, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20149619, Length=232, Percent_Identity=26.2931034482759, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32455239, Length=173, Percent_Identity=30.0578034682081, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI5031765, Length=173, Percent_Identity=30.0578034682081, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=29.3814432989691, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=263, Percent_Identity=33.8403041825095, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=33.4600760456274, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=30.3501945525292, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=30.3030303030303, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=28.4615384615385, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786812, Length=265, Percent_Identity=30.9433962264151, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788459, Length=260, Percent_Identity=30.3846153846154, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI2367175, Length=265, Percent_Identity=29.0566037735849, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=25.390625, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789378, Length=271, Percent_Identity=23.9852398523985, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=24.6212121212121, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367365, Length=263, Percent_Identity=27.3764258555133, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=166, Percent_Identity=29.5180722891566, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=279, Percent_Identity=30.4659498207885, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=27.8195488721804, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=31.2727272727273, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=274, Percent_Identity=30.6569343065693, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=29.8850574712644, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=30.6201550387597, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=28.7822878228782, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=278, Percent_Identity=30.2158273381295, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=277, Percent_Identity=29.9638989169675, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=29.0441176470588, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=30, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=28.6764705882353, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=26.9230769230769, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=276, Percent_Identity=26.8115942028986, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=282, Percent_Identity=28.0141843971631, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=276, Percent_Identity=29.7101449275362, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=173, Percent_Identity=31.7919075144509, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=27.1375464684015, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=201, Percent_Identity=27.8606965174129, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=27.536231884058, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=24.21875, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=28.5185185185185, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=29.520295202952, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=270, Percent_Identity=25.5555555555556, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=29.2307692307692, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=28.0442804428044, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=272, Percent_Identity=27.2058823529412, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=28.1853281853282, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=186, Percent_Identity=28.494623655914, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=270, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=215, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=23.0769230769231, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=35.6862745098039, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=32.4324324324324, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=32.183908045977, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI23397609, Length=262, Percent_Identity=31.2977099236641, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=25.5813953488372, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=28.7937743190661, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358495, Length=239, Percent_Identity=26.7782426778243, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24644337, Length=268, Percent_Identity=32.4626865671642, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859837, Length=217, Percent_Identity=27.6497695852535, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640492, Length=176, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=25.968992248062, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281364892, Length=169, Percent_Identity=26.6272189349112, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.25 [H]

Molecular weight: Translated: 29527; Mature: 29527

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00061 ADH_SHORT ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MRPEDADLDVRAGNRLRGKTVIITGAGRGIGRAAARRMATEGAQLLLADLNAETLDQVIQ
CCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHEEEECCCHHHHHHHHH
ETSEITTSSAFTGDLMQYATAEKLISTCLERYGQVDVLVNNIGGATALKPLWDWSDEEIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHCHHHCCCHHHHH
AEMNRSILPTVWCCRAVLPTMIEQGQGRIVNVGAESVRNGLWDRAPYNMAKGAVHALTTS
HHHCCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHH
IARETADKGILCNCVAPAATGRTDGRLERRVDRKRSPEELAHIARINEMMLDSIPLGRPA
HHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
YPEEQAAAIAFLASDDASFITGQVLSVNGGSSML
CCCHHHHEEEEEECCCCCEEECEEEEECCCCCCC
>Mature Secondary Structure
MRPEDADLDVRAGNRLRGKTVIITGAGRGIGRAAARRMATEGAQLLLADLNAETLDQVIQ
CCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHEEEECCCHHHHHHHHH
ETSEITTSSAFTGDLMQYATAEKLISTCLERYGQVDVLVNNIGGATALKPLWDWSDEEIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHCHHHCCCHHHHH
AEMNRSILPTVWCCRAVLPTMIEQGQGRIVNVGAESVRNGLWDRAPYNMAKGAVHALTTS
HHHCCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHH
IARETADKGILCNCVAPAATGRTDGRLERRVDRKRSPEELAHIARINEMMLDSIPLGRPA
HHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
YPEEQAAAIAFLASDDASFITGQVLSVNGGSSML
CCCHHHHEEEEEECCCCCEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1740120 [H]