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The map label for this gene is caiD [C]

Identifier: 119716358

GI number: 119716358

Start: 2275946

End: 2276941

Strand: Reverse

Name: caiD [C]

Synonym: Noca_2127

Alternate gene names: 119716358

Gene position: 2276941-2275946 (Counterclockwise)

Preceding gene: 119716364

Following gene: 119716357

Centisome position: 45.67

GC content: 63.45

Gene sequence:

>996_bases
GTGGCCGGTTCCGGAATCGACATCGTCGTCGCCGACCGGGTGGGGTGGATCCGACTCGACAGACCAGAGGCGTTGAACGC
CCTGACCCTCGAAATGGTGACCTCCATGCGAGCAGCTCTCGCGCACTGGGAGACGGATCCGCAGATCGACTCCTACCTAG
TCACCGGCGAAGGCCGCGCATTCTGCGCAGGCGGCGACGTGCGGTGGATCGTCGAGGAGATCGCAGAACGGCCCGACAAC
GTCCGCGCCTTCTGGCGAGCCGAATATGACCTCGACCTGGCCATCCATCAGCTACATAAACCATACGTCGCAGTCATGGA
TGGCATCGTCATGGGAGGCGGAGTAGGTATCTCAGCGCACGGCCGACACCGCATCGTCACCGAACGCACCCGCCTGGCAA
TGCCCGAACTACGTATCGGATTCTGCCCAGACGTCGGTGGAACGCGATTGCTCGCCAACGCACCGGGAGAGGTCGGGCTC
CACGTTGCTCTCACCTCGGCGTCCCTTGAGGCCGCCGACATCATCTACTGCGGACTCGCCGACCGCGCGATCAACTCTAG
GGATCTTCACTCCTTGCTGGAGTCGCCACCCGGCGTCCTTCGGCTTGCCCAACAGCACCAAGAACCACCGTGTCCGTCCC
TTGCCGCGCAGCGCCCCTGGATTGACGAGTGCTACTCAGCGCCCACGGTCGAGCTCATCCTTGAACGACTCCGATCGCAC
CCCCAGCAGCTCGCCAGAAACGCAGCCACCATCATTGAGTCGCAGCCACCGACCGCGCTCAAGGTAGCCCTGCGAGCACT
ACGCACCGCTCGTCAGGCATCGGACCTCGCGGAGGTGCTAGCCATGGAGTTCGGGATTGTTAGCCGCAGTCTCATTCATC
ACGACTTCACCGAAGGAATCCGGGCAAGGATGGTCGAGAAGCGCTCCCCGGTCTGGCAGCCCGCCACGTTGTCGGAGGTC
ACCGACGCCGCGGTAGCTGAGTTCTTCGACTCCTAG

Upstream 100 bases:

>100_bases
TTAGGTAACACACTCGCACTCCGCAAGAAGTTATAAAGAATCACTATTCTTGATGGGCGTGTCGGCCCCCAGCCGACCTT
CGACCGAAGTGGAGAGCGCT

Downstream 100 bases:

>100_bases
TCGTCGCATGCGTGCAAGCGCTCGGCGAGGAGAACCAAGGCGTCGCCGGGCTCATCCAACATGGCGCGGCCATCATCGTG
ACGGAATCGACGGCATCTTT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAGSGIDIVVADRVGWIRLDRPEALNALTLEMVTSMRAALAHWETDPQIDSYLVTGEGRAFCAGGDVRWIVEEIAERPDN
VRAFWRAEYDLDLAIHQLHKPYVAVMDGIVMGGGVGISAHGRHRIVTERTRLAMPELRIGFCPDVGGTRLLANAPGEVGL
HVALTSASLEAADIIYCGLADRAINSRDLHSLLESPPGVLRLAQQHQEPPCPSLAAQRPWIDECYSAPTVELILERLRSH
PQQLARNAATIIESQPPTALKVALRALRTARQASDLAEVLAMEFGIVSRSLIHHDFTEGIRARMVEKRSPVWQPATLSEV
TDAAVAEFFDS

Sequences:

>Translated_331_residues
MAGSGIDIVVADRVGWIRLDRPEALNALTLEMVTSMRAALAHWETDPQIDSYLVTGEGRAFCAGGDVRWIVEEIAERPDN
VRAFWRAEYDLDLAIHQLHKPYVAVMDGIVMGGGVGISAHGRHRIVTERTRLAMPELRIGFCPDVGGTRLLANAPGEVGL
HVALTSASLEAADIIYCGLADRAINSRDLHSLLESPPGVLRLAQQHQEPPCPSLAAQRPWIDECYSAPTVELILERLRSH
PQQLARNAATIIESQPPTALKVALRALRTARQASDLAEVLAMEFGIVSRSLIHHDFTEGIRARMVEKRSPVWQPATLSEV
TDAAVAEFFDS
>Mature_330_residues
AGSGIDIVVADRVGWIRLDRPEALNALTLEMVTSMRAALAHWETDPQIDSYLVTGEGRAFCAGGDVRWIVEEIAERPDNV
RAFWRAEYDLDLAIHQLHKPYVAVMDGIVMGGGVGISAHGRHRIVTERTRLAMPELRIGFCPDVGGTRLLANAPGEVGLH
VALTSASLEAADIIYCGLADRAINSRDLHSLLESPPGVLRLAQQHQEPPCPSLAAQRPWIDECYSAPTVELILERLRSHP
QQLARNAATIIESQPPTALKVALRALRTARQASDLAEVLAMEFGIVSRSLIHHDFTEGIRARMVEKRSPVWQPATLSEVT
DAAVAEFFDS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=334, Percent_Identity=38.622754491018, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI37594469, Length=286, Percent_Identity=38.4615384615385, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI194097323, Length=188, Percent_Identity=28.7234042553192, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI68989263, Length=239, Percent_Identity=24.6861924686192, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI221142681, Length=191, Percent_Identity=28.2722513089005, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787659, Length=171, Percent_Identity=26.9005847953216, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788682, Length=187, Percent_Identity=27.807486631016, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=330, Percent_Identity=36.6666666666667, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI25144157, Length=330, Percent_Identity=36.6666666666667, Blast_Score=211, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17554946, Length=171, Percent_Identity=29.2397660818713, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=192, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=304, Percent_Identity=25.6578947368421, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=345, Percent_Identity=28.9855072463768, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28571730, Length=325, Percent_Identity=39.6923076923077, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI28571729, Length=325, Percent_Identity=39.6923076923077, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI20129971, Length=177, Percent_Identity=26.5536723163842, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653477, Length=177, Percent_Identity=26.5536723163842, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 36265; Mature: 36134

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSGIDIVVADRVGWIRLDRPEALNALTLEMVTSMRAALAHWETDPQIDSYLVTGEGRA
CCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEE
FCAGGDVRWIVEEIAERPDNVRAFWRAEYDLDLAIHQLHKPYVAVMDGIVMGGGVGISAH
EECCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHHHCCCCCEECCC
GRHRIVTERTRLAMPELRIGFCPDVGGTRLLANAPGEVGLHVALTSASLEAADIIYCGLA
CCCEEEHHHHHHCCCCCCEECCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHEEEECCH
DRAINSRDLHSLLESPPGVLRLAQQHQEPPCPSLAAQRPWIDECYSAPTVELILERLRSH
HHCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHH
PQQLARNAATIIESQPPTALKVALRALRTARQASDLAEVLAMEFGIVSRSLIHHDFTEGI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARMVEKRSPVWQPATLSEVTDAAVAEFFDS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGSGIDIVVADRVGWIRLDRPEALNALTLEMVTSMRAALAHWETDPQIDSYLVTGEGRA
CCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEE
FCAGGDVRWIVEEIAERPDNVRAFWRAEYDLDLAIHQLHKPYVAVMDGIVMGGGVGISAH
EECCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHHHCCCCCEECCC
GRHRIVTERTRLAMPELRIGFCPDVGGTRLLANAPGEVGLHVALTSASLEAADIIYCGLA
CCCEEEHHHHHHCCCCCCEECCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHEEEECCH
DRAINSRDLHSLLESPPGVLRLAQQHQEPPCPSLAAQRPWIDECYSAPTVELILERLRSH
HHCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHH
PQQLARNAATIIESQPPTALKVALRALRTARQASDLAEVLAMEFGIVSRSLIHHDFTEGI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARMVEKRSPVWQPATLSEVTDAAVAEFFDS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA