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The map label for this gene is xylB [H]

Identifier: 119716351

GI number: 119716351

Start: 2267364

End: 2268464

Strand: Direct

Name: xylB [H]

Synonym: Noca_2120

Alternate gene names: 119716351

Gene position: 2267364-2268464 (Clockwise)

Preceding gene: 119716350

Following gene: 119716352

Centisome position: 45.48

GC content: 67.21

Gene sequence:

>1101_bases
ATGACCGTCACCGCTGCCGTTTCCCGTGAGAAGGGCGCGCCGCTCGTCGTCGAGGAGCTGGAGCTGGATGCGCCACGCTC
CACCGAGGTGCGCGTGCGAATGGTGGGTTCCGGGATCTGCCACACCGACGCTGTTGCCCGGGACCGCATCTACCCGGTGC
CCGAGCCGTCGGTCTTCGGACACGAGGGGTCTGGCGTCGTCGAGGAGGTCGGCTCCGATGTGCGTGGCGTGCAGGTGGGG
GACCACGTCGTGCTGGGCCCGTCGTACTGCGGCAAGTGCACCTTCTGCCGAAGCGGTGAGCCGATGTACTGCGAGAACGG
CTTCCCCGAGCTGTTCGGTTGTCGTCGGCACGATGGGACCACGGCCTTCAGCAAGGATGGCGAGATGGTCGGCTCCCACT
TTTTCGGGCAGTCGTCGTTCGCGACCCACGCCAACGTCACCGAGAACAGCGTCATCGTCGTCGACAAGGACGCCCCGCTG
GAGCTGCTCGGCCCACTGGGATGCGGGCTCAACACCGGTGCGGGGGCCGTGCTCAACGAGATGCGGCCGGCGGCCGGGTC
CTCGATTGTCGTCTTCGGTACCGGAGCGGTCGGCTTCGCCGCGCTCATGGCGGCAGCCGCGGTGTCGTGCTCCACGATCA
TCGGCGTCGACATCCACGACTCCCGTCTGGAGCTGGCCCGGGAGCTGGGCGCGACGCACACCATCAACTCCTCGTCCCAG
GACCTGCATGCCGAGCTGGAGAAGATCACCGGCGGGCGGGGCGTGAACTACGCACTGGACACCACCGCGAGGTCAAGCGT
GGTTCGGGACGCTGCCGATGCGCTCGGCAAGCGGGGTGTGCTCATCGCGGTCGGCGCGGCCGCGCCCGGCGATGAGGTCA
GCTTCGAGGTCGGCAACTCTCTGGTCAAGGGCTGGACCTTCAAGACCGTGATCGAGGGGTCGGCAGTGCCGCAGGTGTTC
ATCCCGCGCCTGGTCGACCTGTGGAAGCAGGGCAAGTTCCCCTTCGACAAGCTGGTGAAGACCTACTCCCTGCATGACAT
CAACACCGGCTTCGAGGACTCCGCCTCCGGGGCCGTCATCAAGCCCGTGGTTGCCTACTGA

Upstream 100 bases:

>100_bases
TAGGTCGGACCTCCCATCCGGACCATCCACACTCGCCTCGGTTGCGGAATCCACGGCACGGTCGAAGAATGGTCGGCATC
CAACCGGAGGGAGCTCTCTC

Downstream 100 bases:

>100_bases
CAACGGTCTCGATCGAGATGGCCTGATCTGCACTGCGATCCCGCTGCAGCCGTCCGCCGCGCCGACTCGAGCCATCTGTT
GCTCCGCAGTCAGCGGGAGC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTVTAAVSREKGAPLVVEELELDAPRSTEVRVRMVGSGICHTDAVARDRIYPVPEPSVFGHEGSGVVEEVGSDVRGVQVG
DHVVLGPSYCGKCTFCRSGEPMYCENGFPELFGCRRHDGTTAFSKDGEMVGSHFFGQSSFATHANVTENSVIVVDKDAPL
ELLGPLGCGLNTGAGAVLNEMRPAAGSSIVVFGTGAVGFAALMAAAAVSCSTIIGVDIHDSRLELARELGATHTINSSSQ
DLHAELEKITGGRGVNYALDTTARSSVVRDAADALGKRGVLIAVGAAAPGDEVSFEVGNSLVKGWTFKTVIEGSAVPQVF
IPRLVDLWKQGKFPFDKLVKTYSLHDINTGFEDSASGAVIKPVVAY

Sequences:

>Translated_366_residues
MTVTAAVSREKGAPLVVEELELDAPRSTEVRVRMVGSGICHTDAVARDRIYPVPEPSVFGHEGSGVVEEVGSDVRGVQVG
DHVVLGPSYCGKCTFCRSGEPMYCENGFPELFGCRRHDGTTAFSKDGEMVGSHFFGQSSFATHANVTENSVIVVDKDAPL
ELLGPLGCGLNTGAGAVLNEMRPAAGSSIVVFGTGAVGFAALMAAAAVSCSTIIGVDIHDSRLELARELGATHTINSSSQ
DLHAELEKITGGRGVNYALDTTARSSVVRDAADALGKRGVLIAVGAAAPGDEVSFEVGNSLVKGWTFKTVIEGSAVPQVF
IPRLVDLWKQGKFPFDKLVKTYSLHDINTGFEDSASGAVIKPVVAY
>Mature_365_residues
TVTAAVSREKGAPLVVEELELDAPRSTEVRVRMVGSGICHTDAVARDRIYPVPEPSVFGHEGSGVVEEVGSDVRGVQVGD
HVVLGPSYCGKCTFCRSGEPMYCENGFPELFGCRRHDGTTAFSKDGEMVGSHFFGQSSFATHANVTENSVIVVDKDAPLE
LLGPLGCGLNTGAGAVLNEMRPAAGSSIVVFGTGAVGFAALMAAAAVSCSTIIGVDIHDSRLELARELGATHTINSSSQD
LHAELEKITGGRGVNYALDTTARSSVVRDAADALGKRGVLIAVGAAAPGDEVSFEVGNSLVKGWTFKTVIEGSAVPQVFI
PRLVDLWKQGKFPFDKLVKTYSLHDINTGFEDSASGAVIKPVVAY

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=33.9673913043478, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI71565154, Length=367, Percent_Identity=34.8773841961853, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI71565152, Length=376, Percent_Identity=33.5106382978723, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI4501929, Length=368, Percent_Identity=33.4239130434783, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=33.1521739130435, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI156523966, Length=367, Percent_Identity=31.0626702997275, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4501939, Length=360, Percent_Identity=31.3888888888889, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI71743840, Length=367, Percent_Identity=31.6076294277929, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI262073058, Length=367, Percent_Identity=31.6076294277929, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI156627571, Length=280, Percent_Identity=26.4285714285714, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786552, Length=379, Percent_Identity=32.7176781002639, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788073, Length=357, Percent_Identity=26.0504201680672, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082125, Length=365, Percent_Identity=25.2054794520548, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=26.8518518518519, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790045, Length=355, Percent_Identity=22.5352112676056, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788407, Length=291, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787863, Length=337, Percent_Identity=25.8160237388724, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25146526, Length=386, Percent_Identity=35.2331606217617, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI71997431, Length=388, Percent_Identity=35.0515463917526, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17565904, Length=339, Percent_Identity=34.8082595870207, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17562878, Length=364, Percent_Identity=25.8241758241758, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562584, Length=312, Percent_Identity=25.9615384615385, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71988145, Length=290, Percent_Identity=25.8620689655172, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562582, Length=319, Percent_Identity=26.3322884012539, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320033, Length=370, Percent_Identity=34.3243243243243, Blast_Score=186, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6323099, Length=339, Percent_Identity=24.188790560472, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=348, Percent_Identity=23.8505747126437, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=308, Percent_Identity=24.025974025974, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319955, Length=302, Percent_Identity=26.158940397351, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=297, Percent_Identity=26.5993265993266, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=307, Percent_Identity=23.7785016286645, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=290, Percent_Identity=24.8275862068966, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319949, Length=145, Percent_Identity=31.7241379310345, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI17737895, Length=374, Percent_Identity=32.620320855615, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI17137530, Length=239, Percent_Identity=28.8702928870293, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17737897, Length=217, Percent_Identity=29.0322580645161, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 38357; Mature: 38226

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTAAVSREKGAPLVVEELELDAPRSTEVRVRMVGSGICHTDAVARDRIYPVPEPSVFG
CEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
HEGSGVVEEVGSDVRGVQVGDHVVLGPSYCGKCTFCRSGEPMYCENGFPELFGCRRHDGT
CCCCCHHHHHCCCCCCEEECCEEEECCCCCCCEEEECCCCCEEECCCCHHHHCCCCCCCC
TAFSKDGEMVGSHFFGQSSFATHANVTENSVIVVDKDAPLELLGPLGCGLNTGAGAVLNE
CEECCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCCCCCCCHHHHHH
MRPAAGSSIVVFGTGAVGFAALMAAAAVSCSTIIGVDIHDSRLELARELGATHTINSSSQ
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHHHCCCEECCCCCH
DLHAELEKITGGRGVNYALDTTARSSVVRDAADALGKRGVLIAVGAAAPGDEVSFEVGNS
HHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHCCH
LVKGWTFKTVIEGSAVPQVFIPRLVDLWKQGKFPFDKLVKTYSLHDINTGFEDSASGAVI
HHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEE
KPVVAY
CCEECC
>Mature Secondary Structure 
TVTAAVSREKGAPLVVEELELDAPRSTEVRVRMVGSGICHTDAVARDRIYPVPEPSVFG
EEEEECCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
HEGSGVVEEVGSDVRGVQVGDHVVLGPSYCGKCTFCRSGEPMYCENGFPELFGCRRHDGT
CCCCCHHHHHCCCCCCEEECCEEEECCCCCCCEEEECCCCCEEECCCCHHHHCCCCCCCC
TAFSKDGEMVGSHFFGQSSFATHANVTENSVIVVDKDAPLELLGPLGCGLNTGAGAVLNE
CEECCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCCCCCCCHHHHHH
MRPAAGSSIVVFGTGAVGFAALMAAAAVSCSTIIGVDIHDSRLELARELGATHTINSSSQ
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHHHCCCEECCCCCH
DLHAELEKITGGRGVNYALDTTARSSVVRDAADALGKRGVLIAVGAAAPGDEVSFEVGNS
HHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHCCH
LVKGWTFKTVIEGSAVPQVFIPRLVDLWKQGKFPFDKLVKTYSLHDINTGFEDSASGAVI
HHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEE
KPVVAY
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]