The gene/protein map for NC_008699 is currently unavailable.
Definition Nocardioides sp. JS614 chromosome, complete genome.
Accession NC_008699
Length 4,985,871

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The map label for this gene is braF [H]

Identifier: 119716342

GI number: 119716342

Start: 2256348

End: 2257166

Strand: Reverse

Name: braF [H]

Synonym: Noca_2111

Alternate gene names: 119716342

Gene position: 2257166-2256348 (Counterclockwise)

Preceding gene: 119716343

Following gene: 119716341

Centisome position: 45.27

GC content: 71.06

Gene sequence:

>819_bases
ATGTCCGTGCTTGAGATCGACCGGCTGAGCATCTCGTTCGGGGGGATCCAGGCGCTGCGGGACGTCAGCATCCGCGCCGG
GGAGTGGGAGATCGTGGGGATCATCGGCCCCAACGGCGCCGGCAAGACGACGCTGTTCAACTGCATCACGGGCTTCTACA
CCGCCACGTCCGGCGGCATCCGCTACCGCGGCGCCGACATCACCCGCCTGCCGGTGCACCGGCGCACGGCCCTCGGCATC
GCCCGGACGTTCCAGAACGTCGGCCTGGTCAAGAACGCCACGGTCCGCACCAACCTCGCCACCGCCCAGCACCTCGCGAT
CGACTACGACCCCTGGGCCGGGATCGTCGGCAGCCCCGGGTCGTTCGCCGAGGAGCGTCGGGTGGCCGAGCGCGGGGAGC
TGATCCTCGACCTGCTCGATCTCCGCGACGTGATCGACGAGCGGGTCGCGGACCTGCCCTACGGGCTGCTCAAGCGGGTC
GAGATCGCCGCGGTGCTGGCCACCGACCCCGACCTCCTGCTGCTCGACGAGCCGGGCTCCGGGATGGGCCCGGAGGAGGC
GCGCTCGCTGGGCGACACCCTGCTCCACCTGCGCCGGGAGTTCGGGTTGACCATGGTCCTCATCGACCACCATGTGCCGT
TGGTGACGCGGGTGTCCGATCACGTCTACTGCCTCAACTTCGGCGAGGTGCTCGCCGAAGGCAGGCCCGACGACGTACGC
CGGCACCCCGAGGTCGTCCGCGCCTACCTGGGCGAGGAGCCGGACCACGCAGCTGCCGCGGCCGCGCCCACCCTGGTCGA
CCTGGAGCCGGTGCGATGA

Upstream 100 bases:

>100_bases
CCGGGCGGGATCGGACAGCAGGTGGCGCCGATCCGGGGCTGGCTCGCGGGCCGGCGGTTCGACCGCCACGCCGGTTCGGC
CCACGACGTGGAGGTGTCCG

Downstream 100 bases:

>100_bases
CCGCGCTCCTGGAGGTCCGCGACCTCGTCGTCGGCTACGGCCCGCACCCCGTGTTGCACGGCATCGACTTCGAGGTCCAC
GAGGGCGAGGTCTGCGTGCT

Product: ABC transporter-like protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSVLEIDRLSISFGGIQALRDVSIRAGEWEIVGIIGPNGAGKTTLFNCITGFYTATSGGIRYRGADITRLPVHRRTALGI
ARTFQNVGLVKNATVRTNLATAQHLAIDYDPWAGIVGSPGSFAEERRVAERGELILDLLDLRDVIDERVADLPYGLLKRV
EIAAVLATDPDLLLLDEPGSGMGPEEARSLGDTLLHLRREFGLTMVLIDHHVPLVTRVSDHVYCLNFGEVLAEGRPDDVR
RHPEVVRAYLGEEPDHAAAAAAPTLVDLEPVR

Sequences:

>Translated_272_residues
MSVLEIDRLSISFGGIQALRDVSIRAGEWEIVGIIGPNGAGKTTLFNCITGFYTATSGGIRYRGADITRLPVHRRTALGI
ARTFQNVGLVKNATVRTNLATAQHLAIDYDPWAGIVGSPGSFAEERRVAERGELILDLLDLRDVIDERVADLPYGLLKRV
EIAAVLATDPDLLLLDEPGSGMGPEEARSLGDTLLHLRREFGLTMVLIDHHVPLVTRVSDHVYCLNFGEVLAEGRPDDVR
RHPEVVRAYLGEEPDHAAAAAAPTLVDLEPVR
>Mature_271_residues
SVLEIDRLSISFGGIQALRDVSIRAGEWEIVGIIGPNGAGKTTLFNCITGFYTATSGGIRYRGADITRLPVHRRTALGIA
RTFQNVGLVKNATVRTNLATAQHLAIDYDPWAGIVGSPGSFAEERRVAERGELILDLLDLRDVIDERVADLPYGLLKRVE
IAAVLATDPDLLLLDEPGSGMGPEEARSLGDTLLHLRREFGLTMVLIDHHVPLVTRVSDHVYCLNFGEVLAEGRPDDVRR
HPEVVRAYLGEEPDHAAAAAAPTLVDLEPVR

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0411

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI105990541, Length=232, Percent_Identity=28.0172413793103, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI116734710, Length=213, Percent_Identity=27.6995305164319, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27881501, Length=225, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI30795238, Length=225, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI11967969, Length=229, Percent_Identity=28.82096069869, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI21536376, Length=207, Percent_Identity=25.6038647342995, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI31657092, Length=218, Percent_Identity=27.5229357798165, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789864, Length=250, Percent_Identity=38.4, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1788761, Length=251, Percent_Identity=31.0756972111554, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789593, Length=253, Percent_Identity=31.2252964426877, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786398, Length=231, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082268, Length=250, Percent_Identity=31.6, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788450, Length=253, Percent_Identity=29.6442687747036, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790525, Length=257, Percent_Identity=27.6264591439689, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788472, Length=230, Percent_Identity=27.3913043478261, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081791, Length=241, Percent_Identity=28.2157676348548, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081782, Length=267, Percent_Identity=28.8389513108614, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI87081709, Length=242, Percent_Identity=25.2066115702479, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789032, Length=253, Percent_Identity=28.8537549407115, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994943, Length=269, Percent_Identity=28.996282527881, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI48995001, Length=272, Percent_Identity=27.9411764705882, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789991, Length=233, Percent_Identity=29.1845493562232, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1786319, Length=230, Percent_Identity=29.5652173913043, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787370, Length=242, Percent_Identity=28.099173553719, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787029, Length=242, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790467, Length=243, Percent_Identity=24.2798353909465, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790190, Length=232, Percent_Identity=25.8620689655172, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789672, Length=254, Percent_Identity=24.0157480314961, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786563, Length=226, Percent_Identity=30.0884955752212, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790739, Length=254, Percent_Identity=26.7716535433071, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790544, Length=272, Percent_Identity=27.5735294117647, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787712, Length=240, Percent_Identity=25.8333333333333, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787759, Length=259, Percent_Identity=28.1853281853282, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786872, Length=251, Percent_Identity=25.8964143426295, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789891, Length=245, Percent_Identity=28.9795918367347, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787089, Length=236, Percent_Identity=25.4237288135593, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082267, Length=244, Percent_Identity=24.5901639344262, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787500, Length=231, Percent_Identity=25.974025974026, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788225, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788210, Length=242, Percent_Identity=24.3801652892562, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786253, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786345, Length=244, Percent_Identity=25.8196721311475, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786803, Length=247, Percent_Identity=24.6963562753036, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788644, Length=263, Percent_Identity=29.6577946768061, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787972, Length=269, Percent_Identity=24.907063197026, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87081834, Length=223, Percent_Identity=26.9058295964126, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787548, Length=283, Percent_Identity=23.321554770318, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789873, Length=226, Percent_Identity=30.9734513274336, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994997, Length=254, Percent_Identity=25.5905511811024, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994883, Length=258, Percent_Identity=25.5813953488372, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789963, Length=251, Percent_Identity=24.7011952191235, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789586, Length=253, Percent_Identity=26.4822134387352, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788897, Length=265, Percent_Identity=25.2830188679245, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787792, Length=280, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=26.9058295964126, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1786703, Length=234, Percent_Identity=24.7863247863248, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=239, Percent_Identity=28.0334728033473, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71983523, Length=239, Percent_Identity=25.5230125523013, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=239, Percent_Identity=25.5230125523013, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71983510, Length=239, Percent_Identity=25.5230125523013, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25146777, Length=277, Percent_Identity=23.1046931407942, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221512771, Length=231, Percent_Identity=29.004329004329, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643674, Length=231, Percent_Identity=26.8398268398268, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI161076682, Length=218, Percent_Identity=30.2752293577982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161076684, Length=218, Percent_Identity=30.2752293577982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581617, Length=218, Percent_Identity=30.2752293577982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581615, Length=218, Percent_Identity=30.2752293577982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666092, Length=228, Percent_Identity=26.7543859649123, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85725262, Length=217, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28574533, Length=228, Percent_Identity=26.7543859649123, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 29611; Mature: 29480

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSVLEIDRLSISFGGIQALRDVSIRAGEWEIVGIIGPNGAGKTTLFNCITGFYTATSGGI
CCCEEEEEEEEEHHHHHHHHHCEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCE
RYRGADITRLPVHRRTALGIARTFQNVGLVKNATVRTNLATAQHLAIDYDPWAGIVGSPG
EECCCCEEECCCHHHHHHHHHHHHHHCCCEECCEEEECCCHHHHEEEEECCCCCCCCCCC
SFAEERRVAERGELILDLLDLRDVIDERVADLPYGLLKRVEIAAVLATDPDLLLLDEPGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEECCCCEEEEECCCC
GMGPEEARSLGDTLLHLRREFGLTMVLIDHHVPLVTRVSDHVYCLNFGEVLAEGRPDDVR
CCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECCCCEEEEEHHHHHHCCCCHHHH
RHPEVVRAYLGEEPDHAAAAAAPTLVDLEPVR
HCHHHHHHHHCCCCCCHHHHCCCCEEECCCCC
>Mature Secondary Structure 
SVLEIDRLSISFGGIQALRDVSIRAGEWEIVGIIGPNGAGKTTLFNCITGFYTATSGGI
CCEEEEEEEEEHHHHHHHHHCEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCE
RYRGADITRLPVHRRTALGIARTFQNVGLVKNATVRTNLATAQHLAIDYDPWAGIVGSPG
EECCCCEEECCCHHHHHHHHHHHHHHCCCEECCEEEECCCHHHHEEEEECCCCCCCCCCC
SFAEERRVAERGELILDLLDLRDVIDERVADLPYGLLKRVEIAAVLATDPDLLLLDEPGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEECCCCEEEEECCCC
GMGPEEARSLGDTLLHLRREFGLTMVLIDHHVPLVTRVSDHVYCLNFGEVLAEGRPDDVR
CCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECCCCEEEEEHHHHHHCCCCHHHH
RHPEVVRAYLGEEPDHAAAAAAPTLVDLEPVR
HCHHHHHHHHCCCCCCHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]