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The map label for this gene is guaAA [H]

Identifier: 119716278

GI number: 119716278

Start: 2191715

End: 2192437

Strand: Direct

Name: guaAA [H]

Synonym: Noca_2047

Alternate gene names: 119716278

Gene position: 2191715-2192437 (Clockwise)

Preceding gene: 119716277

Following gene: 119716279

Centisome position: 43.96

GC content: 76.21

Gene sequence:

>723_bases
GTGAGTCGCCCGGCGGTGCTCGTGGTGGAGCACGACCTCGAGTGCCCGCCGGCGTGGGTCGGCACCTGGCTCGTCGAGGC
CGGCTGCGACCTGGACGTGCGCCGCCCCTATGCGGGCGACGAGCTGCCGGGACTCGCGGCGTACGACGGGCTGCTGGTGC
TCGGCGGGCCGATGGGAGCCAACGACGACGACCGGCACGCCTGGCTCGCACCCGTCAAGGAGCTGCTCCGCGAGGCGCGC
GACCGCGCGCTGCCGACGCTGGGCATCTGCCTGGGGCACCAGCTGATCGCCGTCGCGTACGGCGGCACCGTCGAGCGCAA
CCCCCGCGGCCAGCAGGTCGGGCTGCTCGGCGTGGGCTGGACCGACGCGGCCGCCGACGACCGGCTGTTCGGCCCGCTCG
CGACCCCGCGCCGCGGGGTGCAGTGGAACGACGACGTGGTGACCGCGCTGCCGCCCGGTGCCGTCCTCCTGGCCGCGACC
GGCAACGGCGAGGTGCAGGCCGTCCGGTACGCACCCACGGTGTGGGGCGTGCAGCTGCACCCGGAGGTCGACGTACCCGT
GCTGCGGCCGTGGGCGGAGTCCGACCGCGGCTCGCACGAGACCCGGGGCATCGACACCGATGCGGTGCTCCGCGACATCG
ACGCGGCTCGCGCCGAGCTGGACGATGCGTGGCGGCCGCTGGCGGCGGGGTTCGCGGCGCTGACGCAGCGCCCAGCCCGA
TGA

Upstream 100 bases:

>100_bases
AGCACGTCTTCGACTACTTCCTGCGCAACAAGCGCGCGGAGTGGGAGGAGTACCGCGGCCAGGTCTCCGCCTTCGAGCGC
GACCGCATGCTCCCGGTGCT

Downstream 100 bases:

>100_bases
TCCGGCCGGCGACCAGCAAGGGGAGCCTGCTGCGCCTGGGCTTCCAGGACCCCGACGCCGTCCTCGAGGAGCTCGCCGCC
CTCGGCTCGGCCGCGGACCC

Product: glutamine amidotransferase class-I

Products: NA

Alternate protein names: Glutamine amidotransferase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSRPAVLVVEHDLECPPAWVGTWLVEAGCDLDVRRPYAGDELPGLAAYDGLLVLGGPMGANDDDRHAWLAPVKELLREAR
DRALPTLGICLGHQLIAVAYGGTVERNPRGQQVGLLGVGWTDAAADDRLFGPLATPRRGVQWNDDVVTALPPGAVLLAAT
GNGEVQAVRYAPTVWGVQLHPEVDVPVLRPWAESDRGSHETRGIDTDAVLRDIDAARAELDDAWRPLAAGFAALTQRPAR

Sequences:

>Translated_240_residues
MSRPAVLVVEHDLECPPAWVGTWLVEAGCDLDVRRPYAGDELPGLAAYDGLLVLGGPMGANDDDRHAWLAPVKELLREAR
DRALPTLGICLGHQLIAVAYGGTVERNPRGQQVGLLGVGWTDAAADDRLFGPLATPRRGVQWNDDVVTALPPGAVLLAAT
GNGEVQAVRYAPTVWGVQLHPEVDVPVLRPWAESDRGSHETRGIDTDAVLRDIDAARAELDDAWRPLAAGFAALTQRPAR
>Mature_239_residues
SRPAVLVVEHDLECPPAWVGTWLVEAGCDLDVRRPYAGDELPGLAAYDGLLVLGGPMGANDDDRHAWLAPVKELLREARD
RALPTLGICLGHQLIAVAYGGTVERNPRGQQVGLLGVGWTDAAADDRLFGPLATPRRGVQWNDDVVTALPPGAVLLAATG
NGEVQAVRYAPTVWGVQLHPEVDVPVLRPWAESDRGSHETRGIDTDAVLRDIDAARAELDDAWRPLAAGFAALTQRPAR

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR004739 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 25730; Mature: 25599

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPAVLVVEHDLECPPAWVGTWLVEAGCDLDVRRPYAGDELPGLAAYDGLLVLGGPMGA
CCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCEEEECCCCCC
NDDDRHAWLAPVKELLREARDRALPTLGICLGHQLIAVAYGGTVERNPRGQQVGLLGVGW
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEEEECCCCCCCCCCCEEEEEEECC
TDAAADDRLFGPLATPRRGVQWNDDVVTALPPGAVLLAATGNGEVQAVRYAPTVWGVQLH
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCEEEEEEEC
PEVDVPVLRPWAESDRGSHETRGIDTDAVLRDIDAARAELDDAWRPLAAGFAALTQRPAR
CCCCCCEECCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRPAVLVVEHDLECPPAWVGTWLVEAGCDLDVRRPYAGDELPGLAAYDGLLVLGGPMGA
CCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCEEEECCCCCC
NDDDRHAWLAPVKELLREARDRALPTLGICLGHQLIAVAYGGTVERNPRGQQVGLLGVGW
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEEEECCCCCCCCCCCEEEEEEECC
TDAAADDRLFGPLATPRRGVQWNDDVVTALPPGAVLLAATGNGEVQAVRYAPTVWGVQLH
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCEEEEEEEC
PEVDVPVLRPWAESDRGSHETRGIDTDAVLRDIDAARAELDDAWRPLAAGFAALTQRPAR
CCCCCCEECCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]