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The map label for this gene is glnA [H]

Identifier: 119716277

GI number: 119716277

Start: 2190351

End: 2191718

Strand: Direct

Name: glnA [H]

Synonym: Noca_2046

Alternate gene names: 119716277

Gene position: 2190351-2191718 (Clockwise)

Preceding gene: 119716276

Following gene: 119716278

Centisome position: 43.93

GC content: 68.57

Gene sequence:

>1368_bases
GTGGGGAGCAGCCCCGATAGTCTGTGCCGCATGGGTAAGCAGGAGGACTTCGTTCTTCGCGCTCTCGAGGAGCGCGACGT
CCGGTTCGTGCGGCTGTGGTTCACCGACGTGCTCGGGTTCTTGAAGTCGGTGGCGGTCGCGCCGGCCGAGCTGGACGGCG
CCTTCTCCGAGGGGATCGGCTTCGACGGCTCGGCGATCGAGGGCTTCGCGCGGGTCTACGAGGCGGACATGCTCGCGATG
CCGGACCCGTCGACGTTCCAGATCCTGCCCTGGCGGGGCGAGGGCCCGTCCACGGCGCGGATGTTCTGCGACATCATGAT
GCCGGACGGCTCCTCGTCGTACGCCGACCCGCGCCACGTCCTCAAGCGCACGCTCGGCAAGGCCGCCGACCAGGGGTTCA
CCTTCTACACCCACCCCGAGATCGAGTTCTACCTGTTCAAGGACACCCCGGAGGCCGGGGCCGATCCCGAGCCGGTGGAC
CGCAGCGGCTACTTCGACCACACCGCGACCTCCTCGGGCGCGGACTTCCGGCGCGAGGCGATCACGATGCTCGAGTCGAT
GGGCATCTCGGTCGAGTTCAGCCACCACGAGGGCGGGCCCGGCCAGCAGGAGATCGACCTGCGGTACGCCGACGCGCTGA
CCACCGCCGACAACGTGATGACGTTCCGCACCGTGATCCGCGAGGTCGCCCTCGGTCAGGGCGTCTGGGCGACGTTCATG
CCGAAGCCGTTCACCACCCACCCCGGCTCCGGCATGCACACCCACGTGTCGCTGTTCGAGGGCGACCGCAACGCGTTCTT
CGAGGCCGGCGCGGAGTACCAGCTCTCGAAGACCGGCCGGCAGTTCATCGCCGGCGTGCTGCGGCACGCCAACGAGATCA
GCGTGGTCACCAACCAATGGGTCAACAGCTACAAACGGCTGATGTTCGGTGGTGAGGCGCCGTCCTACATCTGCTGGGGC
CACAACAACCGCTCGGCGATGATCCGGGTCCCGATGTACAAGCCCAACAAGGGCCAGTCCACCCGGATCGAGCTGCGCAC
CATCGACGCGGCCTGCAACCCCTACCTCGCCTTCGCGGTGGTGCTGGCCGCGGGCATGAAGGGCATCGCCGAGGGCTACG
ACCTGCCCCGGGAGGCCGAGGACGACGTGTGGGCCCTGACCGAGCGGGAGCGCCAGAGCCTCGGCATCGAGCCGCTGCCG
AAGAGCCTCTCCGAGGCGATCGCCGTGGCCGAGCACTCCGAGCTGCTCGCCGAGACCCTCGGCGAGCACGTCTTCGACTA
CTTCCTGCGCAACAAGCGCGCGGAGTGGGAGGAGTACCGCGGCCAGGTCTCCGCCTTCGAGCGCGACCGCATGCTCCCGG
TGCTGTGA

Upstream 100 bases:

>100_bases
GTCCGCGGCAGCATCGCCTACACCAGCGTCACCCAGGACTGGATGGTCCCGATGCGCCAGGTGTGGGACGGGGTCATGGG
CACGCAGGACGTGCCGATCT

Downstream 100 bases:

>100_bases
GTCGCCCGGCGGTGCTCGTGGTGGAGCACGACCTCGAGTGCCCGCCGGCGTGGGTCGGCACCTGGCTCGTCGAGGCCGGC
TGCGACCTGGACGTGCGCCG

Product: L-glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase 2 [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MGSSPDSLCRMGKQEDFVLRALEERDVRFVRLWFTDVLGFLKSVAVAPAELDGAFSEGIGFDGSAIEGFARVYEADMLAM
PDPSTFQILPWRGEGPSTARMFCDIMMPDGSSSYADPRHVLKRTLGKAADQGFTFYTHPEIEFYLFKDTPEAGADPEPVD
RSGYFDHTATSSGADFRREAITMLESMGISVEFSHHEGGPGQQEIDLRYADALTTADNVMTFRTVIREVALGQGVWATFM
PKPFTTHPGSGMHTHVSLFEGDRNAFFEAGAEYQLSKTGRQFIAGVLRHANEISVVTNQWVNSYKRLMFGGEAPSYICWG
HNNRSAMIRVPMYKPNKGQSTRIELRTIDAACNPYLAFAVVLAAGMKGIAEGYDLPREAEDDVWALTERERQSLGIEPLP
KSLSEAIAVAEHSELLAETLGEHVFDYFLRNKRAEWEEYRGQVSAFERDRMLPVL

Sequences:

>Translated_455_residues
MGSSPDSLCRMGKQEDFVLRALEERDVRFVRLWFTDVLGFLKSVAVAPAELDGAFSEGIGFDGSAIEGFARVYEADMLAM
PDPSTFQILPWRGEGPSTARMFCDIMMPDGSSSYADPRHVLKRTLGKAADQGFTFYTHPEIEFYLFKDTPEAGADPEPVD
RSGYFDHTATSSGADFRREAITMLESMGISVEFSHHEGGPGQQEIDLRYADALTTADNVMTFRTVIREVALGQGVWATFM
PKPFTTHPGSGMHTHVSLFEGDRNAFFEAGAEYQLSKTGRQFIAGVLRHANEISVVTNQWVNSYKRLMFGGEAPSYICWG
HNNRSAMIRVPMYKPNKGQSTRIELRTIDAACNPYLAFAVVLAAGMKGIAEGYDLPREAEDDVWALTERERQSLGIEPLP
KSLSEAIAVAEHSELLAETLGEHVFDYFLRNKRAEWEEYRGQVSAFERDRMLPVL
>Mature_454_residues
GSSPDSLCRMGKQEDFVLRALEERDVRFVRLWFTDVLGFLKSVAVAPAELDGAFSEGIGFDGSAIEGFARVYEADMLAMP
DPSTFQILPWRGEGPSTARMFCDIMMPDGSSSYADPRHVLKRTLGKAADQGFTFYTHPEIEFYLFKDTPEAGADPEPVDR
SGYFDHTATSSGADFRREAITMLESMGISVEFSHHEGGPGQQEIDLRYADALTTADNVMTFRTVIREVALGQGVWATFMP
KPFTTHPGSGMHTHVSLFEGDRNAFFEAGAEYQLSKTGRQFIAGVLRHANEISVVTNQWVNSYKRLMFGGEAPSYICWGH
NNRSAMIRVPMYKPNKGQSTRIELRTIDAACNPYLAFAVVLAAGMKGIAEGYDLPREAEDDVWALTERERQSLGIEPLPK
SLSEAIAVAEHSELLAETLGEHVFDYFLRNKRAEWEEYRGQVSAFERDRMLPVL

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=460, Percent_Identity=27.1739130434783, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1790301, Length=425, Percent_Identity=36.7058823529412, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87081870, Length=447, Percent_Identity=25.503355704698, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50799; Mature: 50668

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSPDSLCRMGKQEDFVLRALEERDVRFVRLWFTDVLGFLKSVAVAPAELDGAFSEGIG
CCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCC
FDGSAIEGFARVYEADMLAMPDPSTFQILPWRGEGPSTARMFCDIMMPDGSSSYADPRHV
CCCHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHH
LKRTLGKAADQGFTFYTHPEIEFYLFKDTPEAGADPEPVDRSGYFDHTATSSGADFRREA
HHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ITMLESMGISVEFSHHEGGPGQQEIDLRYADALTTADNVMTFRTVIREVALGQGVWATFM
HHHHHHCCCEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
PKPFTTHPGSGMHTHVSLFEGDRNAFFEAGAEYQLSKTGRQFIAGVLRHANEISVVTNQW
CCCCCCCCCCCCEEEEEEEECCCHHHHHCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHH
VNSYKRLMFGGEAPSYICWGHNNRSAMIRVPMYKPNKGQSTRIELRTIDAACNPYLAFAV
HHHHHHHHCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHH
VLAAGMKGIAEGYDLPREAEDDVWALTERERQSLGIEPLPKSLSEAIAVAEHSELLAETL
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GEHVFDYFLRNKRAEWEEYRGQVSAFERDRMLPVL
HHHHHHHHHHCCCCCHHHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
GSSPDSLCRMGKQEDFVLRALEERDVRFVRLWFTDVLGFLKSVAVAPAELDGAFSEGIG
CCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCC
FDGSAIEGFARVYEADMLAMPDPSTFQILPWRGEGPSTARMFCDIMMPDGSSSYADPRHV
CCCHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHH
LKRTLGKAADQGFTFYTHPEIEFYLFKDTPEAGADPEPVDRSGYFDHTATSSGADFRREA
HHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ITMLESMGISVEFSHHEGGPGQQEIDLRYADALTTADNVMTFRTVIREVALGQGVWATFM
HHHHHHCCCEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
PKPFTTHPGSGMHTHVSLFEGDRNAFFEAGAEYQLSKTGRQFIAGVLRHANEISVVTNQW
CCCCCCCCCCCCEEEEEEEECCCHHHHHCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHH
VNSYKRLMFGGEAPSYICWGHNNRSAMIRVPMYKPNKGQSTRIELRTIDAACNPYLAFAV
HHHHHHHHCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHH
VLAAGMKGIAEGYDLPREAEDDVWALTERERQSLGIEPLPKSLSEAIAVAEHSELLAETL
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GEHVFDYFLRNKRAEWEEYRGQVSAFERDRMLPVL
HHHHHHHHHHCCCCCHHHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA