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The map label for this gene is fabH1 [H]

Identifier: 119716221

GI number: 119716221

Start: 2125883

End: 2126887

Strand: Reverse

Name: fabH1 [H]

Synonym: Noca_1989

Alternate gene names: 119716221

Gene position: 2126887-2125883 (Counterclockwise)

Preceding gene: 119716222

Following gene: 119716220

Centisome position: 42.66

GC content: 72.34

Gene sequence:

>1005_bases
ATGGCCACGATCATCGAGCAGGCCGAGGGGGCCCGGCACGCCGGGATCCTCGGCGTCGGCTCCTACCGGCCGTCCCGGGT
GATCCCCAACGCCGACGTCGTCGAGGCGATCGACTCCAGCGACGAGTGGATCCAGCAGCGCTCCGGCATCAAGCAGCGCC
GCTGGGCGACGCCCGAGGAGACCGTGCAGGTGATGTCGGTCGCGGCCGCGCGCAAGGCGCTCGAGCGCGCCTCGGTCGAC
CCCCGGCAGATCGACTGCGTGATCGTCGCGACCGTCACCCACATGATCCAGACGCCGGCCATCGCGACCGCGATCGCCTA
CGAGCTCGGCACCGACCAGGCCGCCGCGTTCGACATCTCCGCCGCGTGCGCGGGCTTCTGCCACGGGGTCGCGATGGCGG
CCGACATGATCCGTGGCGGCAGCGCCGGGCACGTGCTCGTGATCGGCGTCGAGCGGCTCTCCGACCTCACCGACGTCGGC
GACCGCGGCACCGCCTTCATCTTCGCCGACGGCGCCGGCGCCGCGGTGGTCGGCCCCACCGACGCCCCCGGCATCGGCCC
GGTCGTCTGGGGCTCGGACGGCGAGCAGTTCGAGCTGATCCGCCAGCGCGAGGACTGGCGCGACGTCGTGGCCAGCGAGC
GCCCCGAGATGCCGCACCTGGTCATGCAGGGCAACGCGGTGTTCCGCTGGGCGTCGTACTCGATGGCGAAGATCGGCCAG
CTCGCGCTCGACCGTGCCGGCATCGGCATCGACGACCTCGACGTGTTCGTCCCCCACCAGGCCAACATGCGGATCACCGA
CGCCATGGCGCGGGCCATGAAGCTGCCCGAGCGGGTCAAGATCGCCCGCGACATCGCCGAGCAGGGCAACACCTCGGCCG
CCTCCATCCCGCTCGCCCTCGACCGGATGATCGAGGAGGGCGAGGCGCGCAGCGGCGACAAGGCCCTCCTGATCGCCTTC
GGTGCCGGCCTCGCGTACGCCGCGCAGGTCGTCATCGTCCCGTAG

Upstream 100 bases:

>100_bases
CGGCGCACGGCGGCACCGTCGTCGAGTGGCTCGTCGAGGACGGCGACCTGGTCTCGCCGGGCCAACCACTGCTGCGTCTG
CACCCCGAGGGAGGAGCCTG

Downstream 100 bases:

>100_bases
TTCCCAGCAACCCAACCGAAAGGCAGTACCCCGATGGCAACGACCGAAGAGATCCGCGCCGACCTCGCTGACATCGTCAA
CGAGGTCGCCGGCATCGACG

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 1; Beta-ketoacyl-ACP synthase III 1; KAS III 1 [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MATIIEQAEGARHAGILGVGSYRPSRVIPNADVVEAIDSSDEWIQQRSGIKQRRWATPEETVQVMSVAAARKALERASVD
PRQIDCVIVATVTHMIQTPAIATAIAYELGTDQAAAFDISAACAGFCHGVAMAADMIRGGSAGHVLVIGVERLSDLTDVG
DRGTAFIFADGAGAAVVGPTDAPGIGPVVWGSDGEQFELIRQREDWRDVVASERPEMPHLVMQGNAVFRWASYSMAKIGQ
LALDRAGIGIDDLDVFVPHQANMRITDAMARAMKLPERVKIARDIAEQGNTSAASIPLALDRMIEEGEARSGDKALLIAF
GAGLAYAAQVVIVP

Sequences:

>Translated_334_residues
MATIIEQAEGARHAGILGVGSYRPSRVIPNADVVEAIDSSDEWIQQRSGIKQRRWATPEETVQVMSVAAARKALERASVD
PRQIDCVIVATVTHMIQTPAIATAIAYELGTDQAAAFDISAACAGFCHGVAMAADMIRGGSAGHVLVIGVERLSDLTDVG
DRGTAFIFADGAGAAVVGPTDAPGIGPVVWGSDGEQFELIRQREDWRDVVASERPEMPHLVMQGNAVFRWASYSMAKIGQ
LALDRAGIGIDDLDVFVPHQANMRITDAMARAMKLPERVKIARDIAEQGNTSAASIPLALDRMIEEGEARSGDKALLIAF
GAGLAYAAQVVIVP
>Mature_333_residues
ATIIEQAEGARHAGILGVGSYRPSRVIPNADVVEAIDSSDEWIQQRSGIKQRRWATPEETVQVMSVAAARKALERASVDP
RQIDCVIVATVTHMIQTPAIATAIAYELGTDQAAAFDISAACAGFCHGVAMAADMIRGGSAGHVLVIGVERLSDLTDVGD
RGTAFIFADGAGAAVVGPTDAPGIGPVVWGSDGEQFELIRQREDWRDVVASERPEMPHLVMQGNAVFRWASYSMAKIGQL
ALDRAGIGIDDLDVFVPHQANMRITDAMARAMKLPERVKIARDIAEQGNTSAASIPLALDRMIEEGEARSGDKALLIAFG
AGLAYAAQVVIVP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=38.9408099688474, Blast_Score=211, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35439; Mature: 35308

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIIEQAEGARHAGILGVGSYRPSRVIPNADVVEAIDSSDEWIQQRSGIKQRRWATPEE
CCCHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCHHHCCCCHHH
TVQVMSVAAARKALERASVDPRQIDCVIVATVTHMIQTPAIATAIAYELGTDQAAAFDIS
HHHHHHHHHHHHHHHHCCCCCHHCCEEHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHH
AACAGFCHGVAMAADMIRGGSAGHVLVIGVERLSDLTDVGDRGTAFIFADGAGAAVVGPT
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEECCCCEEEECCC
DAPGIGPVVWGSDGEQFELIRQREDWRDVVASERPEMPHLVMQGNAVFRWASYSMAKIGQ
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEECCCCHHHHHH
LALDRAGIGIDDLDVFVPHQANMRITDAMARAMKLPERVKIARDIAEQGNTSAASIPLAL
HHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHCCHHHH
DRMIEEGEARSGDKALLIAFGAGLAYAAQVVIVP
HHHHHHCCCCCCCCEEEEEECCCHHHEEEEEEEC
>Mature Secondary Structure 
ATIIEQAEGARHAGILGVGSYRPSRVIPNADVVEAIDSSDEWIQQRSGIKQRRWATPEE
CCHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCHHHCCCCHHH
TVQVMSVAAARKALERASVDPRQIDCVIVATVTHMIQTPAIATAIAYELGTDQAAAFDIS
HHHHHHHHHHHHHHHHCCCCCHHCCEEHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHH
AACAGFCHGVAMAADMIRGGSAGHVLVIGVERLSDLTDVGDRGTAFIFADGAGAAVVGPT
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEECCCCEEEECCC
DAPGIGPVVWGSDGEQFELIRQREDWRDVVASERPEMPHLVMQGNAVFRWASYSMAKIGQ
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEECCCCHHHHHH
LALDRAGIGIDDLDVFVPHQANMRITDAMARAMKLPERVKIARDIAEQGNTSAASIPLAL
HHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHCCHHHH
DRMIEEGEARSGDKALLIAFGAGLAYAAQVVIVP
HHHHHHCCCCCCCCEEEEEECCCHHHEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]