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The map label for this gene is fabD [H]

Identifier: 119716222

GI number: 119716222

Start: 2126887

End: 2128086

Strand: Reverse

Name: fabD [H]

Synonym: Noca_1990

Alternate gene names: 119716222

Gene position: 2128086-2126887 (Counterclockwise)

Preceding gene: 119716223

Following gene: 119716221

Centisome position: 42.68

GC content: 75.0

Gene sequence:

>1200_bases
GTGCTCGTCATCGTCGCTCCCGGCCAGGGTGCCCAGTCCCCCGGCTTCCTCCGGCCGTGGCTCGAGGACCCGACGTTCGC
CTCCCGGTTCGCCTGGCTCTCGACCGTCGCGGGCCTCGACCTGGCCCACTACGGCACCGAGGCCGACGCGGAGACGATCC
GCGCGACCGAGATCGCCCAGCCGCTGCTCGTCGCGACCGGCCTCGTGGCGGCCCTGGAGCTGTTCCCGAGCCCGGCCGAC
GCCTTCGAGCAGGTCGGCGCCGTTGCGGGCCACAGCGTGGGCGAGATCGCGGCGGCGGCGGGCGCCCGGGTGATCACCGC
CGAGCAGGCCATGGTCCTGGTCCGCGAACGCGGCAACGCGATGGCGCGGGCGGCCGCGGCGACCCCGACCGGCATGACCG
CCGTCCTTGGTGGCGACCGGGACGAGGTCCTCGCGGCCCTGGCCGAGCACGGCCTGACCCCGGCGAACGACAACGCTGCC
GGCCAGCTGGTCGCCGCCGGCACCCTCGAGCAGCTCGAGGCCCTCGCCGCGCACCCGCCGGCGAAGGCCCGGTTGATGCC
GCTGAGCGTCGCCGGCGCCTTCCACACCCACCACATGGAGCCCGCGGTCGGCCACCTGGCCGCGCTGGCCCGCTCGGTCT
CGGTGCACGACCCGCGCACCCGGGTGATCTCCAACCGCGACGGCCGGGTCGTCCACGACGGCCGCGACGTGCTGGCCCGG
ATCGTCGGCCAGATCGCCAGCCCGGTGCGTTGGGACCTGTGCCTGGAGACCATGGAGGACCTCGGCGTGACCGGCATCCT
CGAGATGCCGCCGGCCGGGACGCTGACCGGGATCGCACGGCGCCGATTTTCGGGGAGTGCCCTGCGCGGGGTCGAGACGT
TCGCGCTCAAGACTCCTGACCAGCTCGACGACGCCCGCGCGTTCTGCGCCAAGCACGGCGAGTCCTCCGGCCTCGGCATC
AGCCCGACCTGGCGGATGGTGGTCTCACCCGCCAAGGGCACCTTCCACCAGGACGGCGCCGCCGCCGGCACCGACGTGCT
CGTGCCGGGCGCGGCCATCGGCGAGGTCGCCAGCCTGCGCGACCGCAGCCGGATCACCGCGGCGCACGGCGGCACCGTCG
TCGAGTGGCTCGTCGAGGACGGCGACCTGGTCTCGCCGGGCCAACCACTGCTGCGTCTGCACCCCGAGGGAGGAGCCTGA

Upstream 100 bases:

>100_bases
CACACCTGAGGCGTCTTTGTAGGAACCCCACAAAGGATCGCCGACCGATTGGTGCGGGCCGGAGGCCAGGTCGGCCCCAG
CTTCCCGGCACAGTGGACGG

Downstream 100 bases:

>100_bases
TGGCCACGATCATCGAGCAGGCCGAGGGGGCCCGGCACGCCGGGATCCTCGGCGTCGGCTCCTACCGGCCGTCCCGGGTG
ATCCCCAACGCCGACGTCGT

Product: (acyl-carrier-protein) S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MLVIVAPGQGAQSPGFLRPWLEDPTFASRFAWLSTVAGLDLAHYGTEADAETIRATEIAQPLLVATGLVAALELFPSPAD
AFEQVGAVAGHSVGEIAAAAGARVITAEQAMVLVRERGNAMARAAAATPTGMTAVLGGDRDEVLAALAEHGLTPANDNAA
GQLVAAGTLEQLEALAAHPPAKARLMPLSVAGAFHTHHMEPAVGHLAALARSVSVHDPRTRVISNRDGRVVHDGRDVLAR
IVGQIASPVRWDLCLETMEDLGVTGILEMPPAGTLTGIARRRFSGSALRGVETFALKTPDQLDDARAFCAKHGESSGLGI
SPTWRMVVSPAKGTFHQDGAAAGTDVLVPGAAIGEVASLRDRSRITAAHGGTVVEWLVEDGDLVSPGQPLLRLHPEGGA

Sequences:

>Translated_399_residues
MLVIVAPGQGAQSPGFLRPWLEDPTFASRFAWLSTVAGLDLAHYGTEADAETIRATEIAQPLLVATGLVAALELFPSPAD
AFEQVGAVAGHSVGEIAAAAGARVITAEQAMVLVRERGNAMARAAAATPTGMTAVLGGDRDEVLAALAEHGLTPANDNAA
GQLVAAGTLEQLEALAAHPPAKARLMPLSVAGAFHTHHMEPAVGHLAALARSVSVHDPRTRVISNRDGRVVHDGRDVLAR
IVGQIASPVRWDLCLETMEDLGVTGILEMPPAGTLTGIARRRFSGSALRGVETFALKTPDQLDDARAFCAKHGESSGLGI
SPTWRMVVSPAKGTFHQDGAAAGTDVLVPGAAIGEVASLRDRSRITAAHGGTVVEWLVEDGDLVSPGQPLLRLHPEGGA
>Mature_399_residues
MLVIVAPGQGAQSPGFLRPWLEDPTFASRFAWLSTVAGLDLAHYGTEADAETIRATEIAQPLLVATGLVAALELFPSPAD
AFEQVGAVAGHSVGEIAAAAGARVITAEQAMVLVRERGNAMARAAAATPTGMTAVLGGDRDEVLAALAEHGLTPANDNAA
GQLVAAGTLEQLEALAAHPPAKARLMPLSVAGAFHTHHMEPAVGHLAALARSVSVHDPRTRVISNRDGRVVHDGRDVLAR
IVGQIASPVRWDLCLETMEDLGVTGILEMPPAGTLTGIARRRFSGSALRGVETFALKTPDQLDDARAFCAKHGESSGLGI
SPTWRMVVSPAKGTFHQDGAAAGTDVLVPGAAIGEVASLRDRSRITAAHGGTVVEWLVEDGDLVSPGQPLLRLHPEGGA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=29.7658862876254, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1787334, Length=292, Percent_Identity=30.8219178082192, Blast_Score=101, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71984332, Length=265, Percent_Identity=28.6792452830189, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=241, Percent_Identity=29.045643153527, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665753, Length=272, Percent_Identity=30.8823529411765, Blast_Score=98, Evalue=9e-21,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 41267; Mature: 41267

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVIVAPGQGAQSPGFLRPWLEDPTFASRFAWLSTVAGLDLAHYGTEADAETIRATEIAQ
CEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHH
PLLVATGLVAALELFPSPADAFEQVGAVAGHSVGEIAAAAGARVITAEQAMVLVRERGNA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCCCEEEEHHHHHHHHHHCCCH
MARAAAATPTGMTAVLGGDRDEVLAALAEHGLTPANDNAAGQLVAAGTLEQLEALAAHPP
HHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHCCCC
AKARLMPLSVAGAFHTHHMEPAVGHLAALARSVSVHDPRTRVISNRDGRVVHDGRDVLAR
CCCEEEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEECCHHHHHH
IVGQIASPVRWDLCLETMEDLGVTGILEMPPAGTLTGIARRRFSGSALRGVETFALKTPD
HHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCHHCCCHHEEECCCC
QLDDARAFCAKHGESSGLGISPTWRMVVSPAKGTFHQDGAAAGTDVLVPGAAIGEVASLR
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHH
DRSRITAAHGGTVVEWLVEDGDLVSPGQPLLRLHPEGGA
HHHHEEECCCCEEEEEEECCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MLVIVAPGQGAQSPGFLRPWLEDPTFASRFAWLSTVAGLDLAHYGTEADAETIRATEIAQ
CEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHH
PLLVATGLVAALELFPSPADAFEQVGAVAGHSVGEIAAAAGARVITAEQAMVLVRERGNA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCCCEEEEHHHHHHHHHHCCCH
MARAAAATPTGMTAVLGGDRDEVLAALAEHGLTPANDNAAGQLVAAGTLEQLEALAAHPP
HHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHCCCC
AKARLMPLSVAGAFHTHHMEPAVGHLAALARSVSVHDPRTRVISNRDGRVVHDGRDVLAR
CCCEEEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEECCHHHHHH
IVGQIASPVRWDLCLETMEDLGVTGILEMPPAGTLTGIARRRFSGSALRGVETFALKTPD
HHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCHHCCCHHEEECCCC
QLDDARAFCAKHGESSGLGISPTWRMVVSPAKGTFHQDGAAAGTDVLVPGAAIGEVASLR
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHH
DRSRITAAHGGTVVEWLVEDGDLVSPGQPLLRLHPEGGA
HHHHEEECCCCEEEEEEECCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]