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The map label for this gene is adcA [H]

Identifier: 119716169

GI number: 119716169

Start: 2066833

End: 2067768

Strand: Reverse

Name: adcA [H]

Synonym: Noca_1937

Alternate gene names: 119716169

Gene position: 2067768-2066833 (Counterclockwise)

Preceding gene: 119716176

Following gene: 119716168

Centisome position: 41.47

GC content: 73.72

Gene sequence:

>936_bases
ATGATTCTCATGAAGAGACTTGCCGCCACCATCCCCGTCACGCTCGCGCTCACCGGGCTCACTCTCACCGGGTGCGCGGC
GTTCACCGACGACGGCGGCGGCCCCGCCTCCGCTGCCGGCAAGGGGGCCGGCGGGGTCCGGGTCGCGGCGGCGTTCTACC
CGCTCGCGTACGTCGCCGACCGGGTCGGCGGTGACCACGTCGACGTCACGAACCTCACCGCACCGGGCGGCGAGCCGCAC
GACCTCGAGCCGTCGGTCGCGGTGACCGCCGAGGTCGCCGGGGCCGGGCTCGTCGTCTACGAGCGCGGCTTCCAGCCGGC
GGTCGACGCCGCGGTGGACGAGAACGCGGCCGGCGACGTCCTGGACGCGGCCGGCGTCGTCGACCTGGTGCCGTTCCGCG
AGCACGGAGTCGACTCCGACGAGACCGACCCGCACTTCTGGCTCGACCCGCTGCTGCTCGCCGACGTCGCCGACGCCGTC
GCCGACCGGCTCGAACAGGCCGACCCGGACCACGCCGCGGACTACCGCGCGAACGCCGCCGACCTGCGCGGCGACCTCGA
GGGACTCGACCAGGAGTACGCCGACGGCCTCGCGAGCTGCACCCGCACCACCGTCGTCGTCAGCCACGACGCGTTCGGCT
ACCTGCAGCGCTACGGCGTCGAGATGGAGGCGATCCTCGGCCTCTCCCCCGAGGCCGAGCCGACCCCGGCCGACCTGGCC
CGGCTGCAGGCCCTGATCCGCGCGGACGGGGTCACCACCGTCTTCTCCGAGTCGATCGTCAGCGCCAAGGCGGCCGAGGC
CCTCGCCCGGGAGACCGGCGCGGAGAGCGACGTGCTCGACCCGATCGAGGGGCTGACCGACCGCACCGCCGACGAGGACT
ACCTTTCCCTCATGCGCGCCAACCTCGCCGCCCTCGAGAAGGCGAACGACTGTTGA

Upstream 100 bases:

>100_bases
AGCAACCTAGGAGTCCGCCTCGCGGCGCGGTAATAGCCCGAACGGGCCACCCCGGACGAACGACCTCCGAGTTTGACAAT
CATTCTCAATCTGGCTGAGA

Downstream 100 bases:

>100_bases
GCGCGCCCGCACCAGGATCGGCCACCGGGCCCGTCGTCGAGCTCAGCGGCGGCGCCGTCGCCATCGCGGGCCGCCCGATC
CTGCGCGGCATCGACCTCAC

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MILMKRLAATIPVTLALTGLTLTGCAAFTDDGGGPASAAGKGAGGVRVAAAFYPLAYVADRVGGDHVDVTNLTAPGGEPH
DLEPSVAVTAEVAGAGLVVYERGFQPAVDAAVDENAAGDVLDAAGVVDLVPFREHGVDSDETDPHFWLDPLLLADVADAV
ADRLEQADPDHAADYRANAADLRGDLEGLDQEYADGLASCTRTTVVVSHDAFGYLQRYGVEMEAILGLSPEAEPTPADLA
RLQALIRADGVTTVFSESIVSAKAAEALARETGAESDVLDPIEGLTDRTADEDYLSLMRANLAALEKANDC

Sequences:

>Translated_311_residues
MILMKRLAATIPVTLALTGLTLTGCAAFTDDGGGPASAAGKGAGGVRVAAAFYPLAYVADRVGGDHVDVTNLTAPGGEPH
DLEPSVAVTAEVAGAGLVVYERGFQPAVDAAVDENAAGDVLDAAGVVDLVPFREHGVDSDETDPHFWLDPLLLADVADAV
ADRLEQADPDHAADYRANAADLRGDLEGLDQEYADGLASCTRTTVVVSHDAFGYLQRYGVEMEAILGLSPEAEPTPADLA
RLQALIRADGVTTVFSESIVSAKAAEALARETGAESDVLDPIEGLTDRTADEDYLSLMRANLAALEKANDC
>Mature_311_residues
MILMKRLAATIPVTLALTGLTLTGCAAFTDDGGGPASAAGKGAGGVRVAAAFYPLAYVADRVGGDHVDVTNLTAPGGEPH
DLEPSVAVTAEVAGAGLVVYERGFQPAVDAAVDENAAGDVLDAAGVVDLVPFREHGVDSDETDPHFWLDPLLLADVADAV
ADRLEQADPDHAADYRANAADLRGDLEGLDQEYADGLASCTRTTVVVSHDAFGYLQRYGVEMEAILGLSPEAEPTPADLA
RLQALIRADGVTTVFSESIVSAKAAEALARETGAESDVLDPIEGLTDRTADEDYLSLMRANLAALEKANDC

Specific function: Part of the ATP-driven transport system AdcABC for zinc. Required for transformability [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 32203; Mature: 32203

Theoretical pI: Translated: 3.91; Mature: 3.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMKRLAATIPVTLALTGLTLTGCAAFTDDGGGPASAAGKGAGGVRVAAAFYPLAYVAD
CHHHHHHHHHCCHHHHHHCHHHEEEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
RVGGDHVDVTNLTAPGGEPHDLEPSVAVTAEVAGAGLVVYERGFQPAVDAAVDENAAGDV
HCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHCCCCCCCH
LDAAGVVDLVPFREHGVDSDETDPHFWLDPLLLADVADAVADRLEQADPDHAADYRANAA
HHHCCHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHH
DLRGDLEGLDQEYADGLASCTRTTVVVSHDAFGYLQRYGVEMEAILGLSPEAEPTPADLA
HHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHH
RLQALIRADGVTTVFSESIVSAKAAEALARETGAESDVLDPIEGLTDRTADEDYLSLMRA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCHHHHHHCCCCCHHHHHHHHH
NLAALEKANDC
HHHHHHHCCCC
>Mature Secondary Structure
MILMKRLAATIPVTLALTGLTLTGCAAFTDDGGGPASAAGKGAGGVRVAAAFYPLAYVAD
CHHHHHHHHHCCHHHHHHCHHHEEEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
RVGGDHVDVTNLTAPGGEPHDLEPSVAVTAEVAGAGLVVYERGFQPAVDAAVDENAAGDV
HCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHCCCCCCCH
LDAAGVVDLVPFREHGVDSDETDPHFWLDPLLLADVADAVADRLEQADPDHAADYRANAA
HHHCCHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHH
DLRGDLEGLDQEYADGLASCTRTTVVVSHDAFGYLQRYGVEMEAILGLSPEAEPTPADLA
HHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHH
RLQALIRADGVTTVFSESIVSAKAAEALARETGAESDVLDPIEGLTDRTADEDYLSLMRA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCHHHHHHCCCCCHHHHHHHHH
NLAALEKANDC
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]