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The map label for this gene is fur [H]

Identifier: 119716166

GI number: 119716166

Start: 2064569

End: 2064976

Strand: Reverse

Name: fur [H]

Synonym: Noca_1934

Alternate gene names: 119716166

Gene position: 2064976-2064569 (Counterclockwise)

Preceding gene: 119716167

Following gene: 119716160

Centisome position: 41.42

GC content: 74.02

Gene sequence:

>408_bases
ATGACGAGCACTGAGCACGCGGAGACCCCGCGCCTGCGCCCGACCCGCCAGCGCCGCGCCGTCACCGAGGCGCTCGACTC
GTTCAGCGACTTCCGCTCGGCCCAGGAGATCCACGAGCTGCTCGGCCGCCGCGGCGAGACCGTCGGGCTGGCCACGGTCT
ACCGCACCCTGCAGCGGCTCGCCGAGGCCGGCGACGTCGACGTGCTGCGCACCGAGGACGGCGAGGCGATCTACCGGCGC
TGCTCCGAGGCGCACCACCACCACCTGGTCTGCCGCTCGTGCGGCGCGACGGTCGAGGTGGAGGGTCCCGCGGTGGAGCG
GTGGACGAGGGCGATCGCCGCCGAGCACGGGTACGCCGAGGTCAGCCACACACTGGAGATCTTCGGCACCTGCGCGCGCT
GCGGCTGA

Upstream 100 bases:

>100_bases
CACGAGCACGGCGAGGACTGCGGTCACGTGGCGGTCCAGCACGGCGACCACGTCGACTACGTCCACGACGGCCACCGGCA
CGCCCCGCACGGGAGGCACT

Downstream 100 bases:

>100_bases
GCGCCGTACTCACACCGCCGGGCTCAGGCGTCCAGGGGCAGCCGCACGCGGAACACGCTGCCCCTGCCGAGCTCGCTCTC
GACCTCGATCCGGCCACCGT

Product: zinc uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MTSTEHAETPRLRPTRQRRAVTEALDSFSDFRSAQEIHELLGRRGETVGLATVYRTLQRLAEAGDVDVLRTEDGEAIYRR
CSEAHHHHLVCRSCGATVEVEGPAVERWTRAIAAEHGYAEVSHTLEIFGTCARCG

Sequences:

>Translated_135_residues
MTSTEHAETPRLRPTRQRRAVTEALDSFSDFRSAQEIHELLGRRGETVGLATVYRTLQRLAEAGDVDVLRTEDGEAIYRR
CSEAHHHHLVCRSCGATVEVEGPAVERWTRAIAAEHGYAEVSHTLEIFGTCARCG
>Mature_134_residues
TSTEHAETPRLRPTRQRRAVTEALDSFSDFRSAQEIHELLGRRGETVGLATVYRTLQRLAEAGDVDVLRTEDGEAIYRRC
SEAHHHHLVCRSCGATVEVEGPAVERWTRAIAAEHGYAEVSHTLEIFGTCARCG

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=122, Percent_Identity=35.2459016393443, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15059; Mature: 14928

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTEHAETPRLRPTRQRRAVTEALDSFSDFRSAQEIHELLGRRGETVGLATVYRTLQRL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AEAGDVDVLRTEDGEAIYRRCSEAHHHHLVCRSCGATVEVEGPAVERWTRAIAAEHGYAE
HCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCHHH
VSHTLEIFGTCARCG
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSTEHAETPRLRPTRQRRAVTEALDSFSDFRSAQEIHELLGRRGETVGLATVYRTLQRL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AEAGDVDVLRTEDGEAIYRRCSEAHHHHLVCRSCGATVEVEGPAVERWTRAIAAEHGYAE
HCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCHHH
VSHTLEIFGTCARCG
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406286; 11586360; 12142430 [H]