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The map label for this gene is uppS2 [H]

Identifier: 119716164

GI number: 119716164

Start: 2062114

End: 2062929

Strand: Direct

Name: uppS2 [H]

Synonym: Noca_1932

Alternate gene names: 119716164

Gene position: 2062114-2062929 (Clockwise)

Preceding gene: 119716163

Following gene: 119716165

Centisome position: 41.36

GC content: 72.67

Gene sequence:

>816_bases
GTGCGCCAGCCCACGCCGCACCCGACGGGGGCGCGCCCCCCGGCGATCCCACGAGAGCTCGTGCCCCGGCACGTCGCCAT
CGTCATGGACGGCAACGGCCGCTGGGCCAAGGAGCGCGGGCTGCCGCGGACCAAGGGCCACGAGCGTGGCGAGCACTCAC
TGTTCGACGTCGTCGAGGGCGCCATCGAGATCGGGGTCAAGGCGATCTCGGCGTACGCGTTCTCCACCGAGAACTGGTCG
CGCTCGCCCGACGAGGTGCGCTTCCTCATGGGCTTCAACCGTGACGTGATCCGCCGCCGTCGGGACGAGATGCACGAGCT
CGGTGTCCGGGTGCGGTGGGCCGGGCGTGCGCCGCGGCTGTGGAAGTCGGTGATCCGGGAGCTGCAGGTCGCCGAGGAGC
TCACCCGCCGCAACGACGTGCTCACCTTGACGATGTGCGTCAACTACGGCGGGCGCGCCGAGCTCGCCGACACCGCACGC
AGCATCGCCCGCGAGGTCGCCGCCGGACGGCTGGACCCCGAGAAGGTCGACGAGAAGGTCTTCGCGCGGCACCTCTACGT
CCCCGAGCTCGCCGACGCGGACCTGGTCTGGCGGACCTCGGGTGAGCAGCGGCTGTCCAACTTCATGCTGTGGCAGGCGG
CGTACTCCGAGCTGGTCTTCACCGACGTGCTGTGGCCCGACGTCGACCGGCGCCACCTCTGGCACGCGATCGAGCTCTAC
GCGAGCCGGGACCGCCGGTACGGCGGCGCCGCCCCGAACCCCGTGCCGGGACCGAGCCAGGGCCCCGTCGCCGCCCCGGC
GCCGGGCGAGGACTGA

Upstream 100 bases:

>100_bases
CGGCCGGGGCAGCGAGTTCCGGGTCGTGCTCCCGTCGTACGCCGCCCAACTCGCCTCCTGAGGACCGTCCCCCGACTAGG
CTCGCGCCGTGAGACGTGCC

Downstream 100 bases:

>100_bases
GCCGCGCCATGGGGAGGGTGGCGACGAGGCTCGCGGGGTTGCACCGCCGGCTGCTGTTCGCCGACGACCCGGATCCGGAG
CTGCTCCAGGGTGTCTTCGC

Product: undecaprenyl pyrophosphate synthetase

Products: NA

Alternate protein names: UPP synthase 2; Di-trans,poly-cis-decaprenylcistransferase 2; Undecaprenyl diphosphate synthase 2; UDS 2 [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRQPTPHPTGARPPAIPRELVPRHVAIVMDGNGRWAKERGLPRTKGHERGEHSLFDVVEGAIEIGVKAISAYAFSTENWS
RSPDEVRFLMGFNRDVIRRRRDEMHELGVRVRWAGRAPRLWKSVIRELQVAEELTRRNDVLTLTMCVNYGGRAELADTAR
SIAREVAAGRLDPEKVDEKVFARHLYVPELADADLVWRTSGEQRLSNFMLWQAAYSELVFTDVLWPDVDRRHLWHAIELY
ASRDRRYGGAAPNPVPGPSQGPVAAPAPGED

Sequences:

>Translated_271_residues
MRQPTPHPTGARPPAIPRELVPRHVAIVMDGNGRWAKERGLPRTKGHERGEHSLFDVVEGAIEIGVKAISAYAFSTENWS
RSPDEVRFLMGFNRDVIRRRRDEMHELGVRVRWAGRAPRLWKSVIRELQVAEELTRRNDVLTLTMCVNYGGRAELADTAR
SIAREVAAGRLDPEKVDEKVFARHLYVPELADADLVWRTSGEQRLSNFMLWQAAYSELVFTDVLWPDVDRRHLWHAIELY
ASRDRRYGGAAPNPVPGPSQGPVAAPAPGED
>Mature_271_residues
MRQPTPHPTGARPPAIPRELVPRHVAIVMDGNGRWAKERGLPRTKGHERGEHSLFDVVEGAIEIGVKAISAYAFSTENWS
RSPDEVRFLMGFNRDVIRRRRDEMHELGVRVRWAGRAPRLWKSVIRELQVAEELTRRNDVLTLTMCVNYGGRAELADTAR
SIAREVAAGRLDPEKVDEKVFARHLYVPELADADLVWRTSGEQRLSNFMLWQAAYSELVFTDVLWPDVDRRHLWHAIELY
ASRDRRYGGAAPNPVPGPSQGPVAAPAPGED

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580742, Length=220, Percent_Identity=35.4545454545455, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI45580738, Length=220, Percent_Identity=35.4545454545455, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1786371, Length=230, Percent_Identity=43.9130434782609, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71993029, Length=225, Percent_Identity=33.7777777777778, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319474, Length=212, Percent_Identity=36.3207547169811, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323748, Length=224, Percent_Identity=33.0357142857143, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI18857969, Length=228, Percent_Identity=36.4035087719298, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 30680; Mature: 30680

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQPTPHPTGARPPAIPRELVPRHVAIVMDGNGRWAKERGLPRTKGHERGEHSLFDVVEG
CCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHH
AIEIGVKAISAYAFSTENWSRSPDEVRFLMGFNRDVIRRRRDEMHELGVRVRWAGRAPRL
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCHH
WKSVIRELQVAEELTRRNDVLTLTMCVNYGGRAELADTARSIAREVAAGRLDPEKVDEKV
HHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
FARHLYVPELADADLVWRTSGEQRLSNFMLWQAAYSELVFTDVLWPDVDRRHLWHAIELY
HHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ASRDRRYGGAAPNPVPGPSQGPVAAPAPGED
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRQPTPHPTGARPPAIPRELVPRHVAIVMDGNGRWAKERGLPRTKGHERGEHSLFDVVEG
CCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHH
AIEIGVKAISAYAFSTENWSRSPDEVRFLMGFNRDVIRRRRDEMHELGVRVRWAGRAPRL
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCHH
WKSVIRELQVAEELTRRNDVLTLTMCVNYGGRAELADTARSIAREVAAGRLDPEKVDEKV
HHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
FARHLYVPELADADLVWRTSGEQRLSNFMLWQAAYSELVFTDVLWPDVDRRHLWHAIELY
HHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ASRDRRYGGAAPNPVPGPSQGPVAAPAPGED
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]