Click here to switch to the map view.

The map label for this gene is ucpA [H]

Identifier: 119716082

GI number: 119716082

Start: 1973486

End: 1974187

Strand: Direct

Name: ucpA [H]

Synonym: Noca_1849

Alternate gene names: 119716082

Gene position: 1973486-1974187 (Clockwise)

Preceding gene: 119716081

Following gene: 119716083

Centisome position: 39.58

GC content: 71.08

Gene sequence:

>702_bases
GTGAGCACCCGGGACAAGGTCGCGATCGTGACCGCGGGCAGCTCGGGCATCGGGGCGGGTATCGTCCGCGCGCTCGCCGA
CGACCACCGGGTGGTGGTGCTGGCTCGGTCCGAGGGGGTGGACCGGATCGCCGCCGAGGTCGACGGGATCGCCGTGCGCG
GCTCGGTCACCGACCGCGCCGACCTGGCGCGAGCGGTCGACGCGGCCAAGGAGCTGGGCCGGATCGACACCGTCGTGATC
AACACCGGACACCCGCCGAAGGGCGACTTGTTGGACCTCACCGACGACGACTGGGAGCTGGGGCTGGATTTGATCTTCCG
CTCGGCGATCCACCTGGTCTCGTTGGTCACCCCGGTGTTCCTCGAGCAGCGCCGCGGCTCGGTCGTGGCGGTCACGTCGT
ACGCCAGCCAGGTGCCGGAGCTGGTGATGCCGGTGTCCAGCGTGCTGCGTGCAGCCCTGCAGAACTGGATCAAGCTCTAC
GCCACGAGGTACGGCGCCGACGGCATCCGCGCGAACAGCGTGCTGCCCGGCTTCATCGCGACCCATCCGGTCGACCCGGA
CCGGCTCGCCTCGATCCCGGCCGGTCGGTACGCCGACCCGCTCGAGCTCGGCCGCGTCGTGGCCTTCCTGGCCTCCGATG
CCGCGTCGTTCGTGAGCGGCCAGAACATCACCGTCGACGGCGGCATGGTCGCCGTCCCCTGA

Upstream 100 bases:

>100_bases
ACCTGATCGCCGGCATCCCGGACCCGGTGCTGGACCCGGCGATCTTCGACCCGCACCGCGGGCTGACCGAGACCCAGGAG
TGGCTGCGGGCGGCCCGGAA

Downstream 100 bases:

>100_bases
GCAGCAAGACCCACCGGAAGGACCCGACATGAGCACGCTCCCTGTCCGCAACATGCCCTTCAACGAGGAGTACACCGGCA
GCAACGGCCCGGTCGCGATC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSTRDKVAIVTAGSSGIGAGIVRALADDHRVVVLARSEGVDRIAAEVDGIAVRGSVTDRADLARAVDAAKELGRIDTVVI
NTGHPPKGDLLDLTDDDWELGLDLIFRSAIHLVSLVTPVFLEQRRGSVVAVTSYASQVPELVMPVSSVLRAALQNWIKLY
ATRYGADGIRANSVLPGFIATHPVDPDRLASIPAGRYADPLELGRVVAFLASDAASFVSGQNITVDGGMVAVP

Sequences:

>Translated_233_residues
MSTRDKVAIVTAGSSGIGAGIVRALADDHRVVVLARSEGVDRIAAEVDGIAVRGSVTDRADLARAVDAAKELGRIDTVVI
NTGHPPKGDLLDLTDDDWELGLDLIFRSAIHLVSLVTPVFLEQRRGSVVAVTSYASQVPELVMPVSSVLRAALQNWIKLY
ATRYGADGIRANSVLPGFIATHPVDPDRLASIPAGRYADPLELGRVVAFLASDAASFVSGQNITVDGGMVAVP
>Mature_232_residues
STRDKVAIVTAGSSGIGAGIVRALADDHRVVVLARSEGVDRIAAEVDGIAVRGSVTDRADLARAVDAAKELGRIDTVVIN
TGHPPKGDLLDLTDDDWELGLDLIFRSAIHLVSLVTPVFLEQRRGSVVAVTSYASQVPELVMPVSSVLRAALQNWIKLYA
TRYGADGIRANSVLPGFIATHPVDPDRLASIPAGRYADPLELGRVVAFLASDAASFVSGQNITVDGGMVAVP

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=32, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=30.8641975308642, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI66933014, Length=174, Percent_Identity=29.8850574712644, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=27.1653543307087, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=32.9787234042553, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=28.0632411067194, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI15277342, Length=148, Percent_Identity=29.0540540540541, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI7705925, Length=236, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI126723191, Length=204, Percent_Identity=32.843137254902, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=32.520325203252, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=30.0813008130081, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=28.2258064516129, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=27.6679841897233, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=29.9595141700405, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.9256198347107, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=31.6239316239316, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786812, Length=195, Percent_Identity=28.2051282051282, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=25.2, Blast_Score=67, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=33.8775510204082, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=26.7716535433071, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=222, Percent_Identity=28.8288288288288, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=28.8389513108614, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=25.609756097561, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=29.9242424242424, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=28.0769230769231, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=28.2868525896414, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=25.5230125523013, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=27.8884462151394, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=24.6031746031746, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=35.7723577235772, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=28.6885245901639, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=28.2157676348548, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=29.8804780876494, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.7086614173228, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24487; Mature: 24356

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRDKVAIVTAGSSGIGAGIVRALADDHRVVVLARSEGVDRIAAEVDGIAVRGSVTDRA
CCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCEEEECCCCCHH
DLARAVDAAKELGRIDTVVINTGHPPKGDLLDLTDDDWELGLDLIFRSAIHLVSLVTPVF
HHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LEQRRGSVVAVTSYASQVPELVMPVSSVLRAALQNWIKLYATRYGADGIRANSVLPGFIA
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
THPVDPDRLASIPAGRYADPLELGRVVAFLASDAASFVSGQNITVDGGMVAVP
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECC
>Mature Secondary Structure 
STRDKVAIVTAGSSGIGAGIVRALADDHRVVVLARSEGVDRIAAEVDGIAVRGSVTDRA
CCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCEEEECCCCCHH
DLARAVDAAKELGRIDTVVINTGHPPKGDLLDLTDDDWELGLDLIFRSAIHLVSLVTPVF
HHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LEQRRGSVVAVTSYASQVPELVMPVSSVLRAALQNWIKLYATRYGADGIRANSVLPGFIA
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
THPVDPDRLASIPAGRYADPLELGRVVAFLASDAASFVSGQNITVDGGMVAVP
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]