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The map label for this gene is rbtD [H]

Identifier: 119716063

GI number: 119716063

Start: 1950013

End: 1950810

Strand: Direct

Name: rbtD [H]

Synonym: Noca_1829

Alternate gene names: 119716063

Gene position: 1950013-1950810 (Clockwise)

Preceding gene: 119716062

Following gene: 119716064

Centisome position: 39.11

GC content: 76.07

Gene sequence:

>798_bases
GTGACGAGGGCGTCCGGCCAGCGCGCCGGACAGGGCGTCGTCGTCACCGGGGCCGCGCGCGGGATCGGCCGCGCGCTCGC
CCGGCGACTCGCCGCCGGCGGTGCCCGCCTGGTGGTCAGCGACGTCGACGCGGACGCGCTGGCCGAGGTCGCTGCCGAGG
TGGGCGGTCTCGCCGTCCCGGGCGACGCCGCCTCGGTCGACGGCGTGGCGGCGCTGGTCGCCCGGGCCGAGGAGCACCTC
GGTGGCATCGACGCCTACTTCGCGAACGCCGGCAGCGACCGCGGCCGAGGGCTGCTCGCCGGCGAGGACGACTGGGCGGC
CAGCCTTGAGGTCAACGTGCTGGCGCACGTCCGCGCCGCACGGCTGCTGGTGCCCCGGTGGCTGGAGCGCGGCGGGGGCC
GGTTCGTGGTCACCGCCTCTGCCGCGGGTCTGCTCACGATGCTCGGCAGCCCGGCGTACTCGGTCAGCAAGCACGGCGCG
GTCGCGTTCGCGGAGTGGCTCGCCGCGACGTACCGGCACCGCGGCATCGTGGTGCAGGCGATCTGCCCGCAGGGCGTGGC
GACCCGGATGCTCGAGGAGTCCGGTGGGCTCGAGGAGATCCTCAGCCACGACTGGGCGCTGAGCCCCGACGAGGTCGCCG
AGGCGGCCTGGACGGCGCTCGCCGACGACCGGTTCCTGGTGCTGCCGCACCCGGAGGTCGAGGGCTACTTCCTCGCCCGC
GCCCAGGACCACTCGCGCTGGCTGGCCGGGATGAACCGGTTGCAGCAGCGCCTCGACCTCCGAGGAGCAGACGCGTGA

Upstream 100 bases:

>100_bases
CCCTGATCAACTCGCTGCAGCACCACGACAGGCAGATCGGTCTCGAGACCATGTGCGTGGGCGGGGGCCAGGGCATGGCG
ATGGTGCTGGAGCGGCTCTC

Downstream 100 bases:

>100_bases
AGGCGTGGCAGGTGGACCGGCTCGGTGAGCCGCGTGAAGTGATGGTGCTCGCCGACGTGGCGGACCCCGAGCCGGGGCCC
GGCCAGCTGGTCGTGCGCGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: RDH [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTRASGQRAGQGVVVTGAARGIGRALARRLAAGGARLVVSDVDADALAEVAAEVGGLAVPGDAASVDGVAALVARAEEHL
GGIDAYFANAGSDRGRGLLAGEDDWAASLEVNVLAHVRAARLLVPRWLERGGGRFVVTASAAGLLTMLGSPAYSVSKHGA
VAFAEWLAATYRHRGIVVQAICPQGVATRMLEESGGLEEILSHDWALSPDEVAEAAWTALADDRFLVLPHPEVEGYFLAR
AQDHSRWLAGMNRLQQRLDLRGADA

Sequences:

>Translated_265_residues
MTRASGQRAGQGVVVTGAARGIGRALARRLAAGGARLVVSDVDADALAEVAAEVGGLAVPGDAASVDGVAALVARAEEHL
GGIDAYFANAGSDRGRGLLAGEDDWAASLEVNVLAHVRAARLLVPRWLERGGGRFVVTASAAGLLTMLGSPAYSVSKHGA
VAFAEWLAATYRHRGIVVQAICPQGVATRMLEESGGLEEILSHDWALSPDEVAEAAWTALADDRFLVLPHPEVEGYFLAR
AQDHSRWLAGMNRLQQRLDLRGADA
>Mature_264_residues
TRASGQRAGQGVVVTGAARGIGRALARRLAAGGARLVVSDVDADALAEVAAEVGGLAVPGDAASVDGVAALVARAEEHLG
GIDAYFANAGSDRGRGLLAGEDDWAASLEVNVLAHVRAARLLVPRWLERGGGRFVVTASAAGLLTMLGSPAYSVSKHGAV
AFAEWLAATYRHRGIVVQAICPQGVATRMLEESGGLEEILSHDWALSPDEVAEAAWTALADDRFLVLPHPEVEGYFLARA
QDHSRWLAGMNRLQQRLDLRGADA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=239, Percent_Identity=28.0334728033473, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI142976729, Length=231, Percent_Identity=27.7056277056277, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI40807363, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI210032110, Length=260, Percent_Identity=28.0769230769231, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI32483357, Length=210, Percent_Identity=33.8095238095238, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI25282469, Length=253, Percent_Identity=25.6916996047431, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40254992, Length=229, Percent_Identity=30.1310043668122, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=178, Percent_Identity=34.8314606741573, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI5031737, Length=205, Percent_Identity=32.1951219512195, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=33.5135135135135, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=28.0701754385965, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=33.5051546391753, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=32.0855614973262, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=26.2295081967213, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=28.75, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787905, Length=188, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=26.1780104712042, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=240, Percent_Identity=29.5833333333333, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=235, Percent_Identity=28.936170212766, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=234, Percent_Identity=29.0598290598291, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=222, Percent_Identity=29.2792792792793, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=191, Percent_Identity=29.8429319371728, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859837, Length=217, Percent_Identity=29.0322580645161, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=227, Percent_Identity=25.9911894273128, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580925, Length=199, Percent_Identity=30.6532663316583, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=25.7309941520468, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.56 [H]

Molecular weight: Translated: 27658; Mature: 27526

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRASGQRAGQGVVVTGAARGIGRALARRLAAGGARLVVSDVDADALAEVAAEVGGLAVP
CCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCEECC
GDAASVDGVAALVARAEEHLGGIDAYFANAGSDRGRGLLAGEDDWAASLEVNVLAHVRAA
CCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEECCCCCCHHEEEHHHHHHHHHH
RLLVPRWLERGGGRFVVTASAAGLLTMLGSPAYSVSKHGAVAFAEWLAATYRHRGIVVQA
HHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHCCEEEEE
ICPQGVATRMLEESGGLEEILSHDWALSPDEVAEAAWTALADDRFLVLPHPEVEGYFLAR
ECCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
AQDHSRWLAGMNRLQQRLDLRGADA
CCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRASGQRAGQGVVVTGAARGIGRALARRLAAGGARLVVSDVDADALAEVAAEVGGLAVP
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCEECC
GDAASVDGVAALVARAEEHLGGIDAYFANAGSDRGRGLLAGEDDWAASLEVNVLAHVRAA
CCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEECCCCCCHHEEEHHHHHHHHHH
RLLVPRWLERGGGRFVVTASAAGLLTMLGSPAYSVSKHGAVAFAEWLAATYRHRGIVVQA
HHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHCCEEEEE
ICPQGVATRMLEESGGLEEILSHDWALSPDEVAEAAWTALADDRFLVLPHPEVEGYFLAR
ECCCHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
AQDHSRWLAGMNRLQQRLDLRGADA
CCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3904726; 2933028; 3891331 [H]