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The map label for this gene is cat2 [H]

Identifier: 119716037

GI number: 119716037

Start: 1915308

End: 1916516

Strand: Direct

Name: cat2 [H]

Synonym: Noca_1803

Alternate gene names: 119716037

Gene position: 1915308-1916516 (Clockwise)

Preceding gene: 119716036

Following gene: 119716038

Centisome position: 38.41

GC content: 70.55

Gene sequence:

>1209_bases
GTGGATCTCGCCCGCGCACTCGCGTCCTTGCCCGCCAACCCGCGGATCGTCATCACCGGCAACCACGCCACGCCCTGGCA
CACGCTGAAGCTCGTCGACGACGCGCTGGACGACTACCGCCTCTGGACGCTCAACGGCCAGCCCGGCCTGCCCGACCGGG
AGGGCGTGGTGCTCGAGACGTCGTTCGTCGGGCCGGCCCAGCGGCGCAACCCGCGGCTGAGCTACGTGCCCTCGCGGCTG
TCGATGGTGCCATCTCTGTTCGGCAAGCAGCTGCCTCCCGACGCGGTGGTCCTGCACACGACCCGGCCGCGGGACGGCAA
GCTCTCCCTCGGCGTCGAGGTGAACGTGCTCCCGGCGGCGATCGAGGCGGTACGCCGCAACGGCGGCGTCGTGATCGCCC
AGGTCAACGACAACATGCCGTGGACGTTCGGGGACGCGCTGATCGACCTCGACCTGGTCGACGTGCTGGTCGACGGGGAC
GAGCCGATGCCGGTCGCGCCGGTCTCCTCGATCGACGCGGCCTCCGCGAAGATCGGCGAGCTGGTCGCCGCCCGGGTCTC
CGACGGCTCGACGCTCCAGGCCGGCATCGGTGCGGTTCCCGATGCGACCATGCACGGGCTCACCGACCGCTCCGGGTTGC
GGGTCTGGACCGAGATGTTCTCCGACAGCGTGCTGGCCCTGGAGAAGGTCGGGGCCCTGGACCGCAACATCCCGATCTCC
GCGTCCTTCCTGTTCGGCTCGCCCGAGCTGCTCGAGTGGGTCGACGGCAACGAGCGGGTCGAGATGGTCCGCACCGAGGT
CACCAACAGCCCGGCCCGGATCGCGCGGAACCCCAAGATGGTCAGCGTCAACACCGCGCTCCAGGTCGACCTGTTCGGCC
AGGCCAACGCCTCGCGGATCAACGCGCGCATCCACTCCGGCTTCGGCGGCCAGACCGACTTCATCGTCGGCGCGATGCAC
AGCGCCGGCGGGCAGGCGTTCATCGCGCTGCGCTCCTGGCACCCGAAGGCCGACTGCTCGACGGTCGTGCCGATGGTCGA
CGAGCCGATCACCTCGTTCCAGATGAGCGCGATCGTCACCGAGCAGGGCCTGGCCACGGTGTTCGGCAACGACCAGCGCG
AGCAGGCTCGCCAGATCATCGAGCACGCCGCCCACCCCAGCGTCCGTGAGGAGCTGCGCGAGGAGGCCGTCGCCCTCGGT
CTGGCCTGA

Upstream 100 bases:

>100_bases
CCGGTTCTGACGGCGCGCGGCGATCCCGAGACCGTCGGCCCGACGGTGCAGGACTTCCGGCCCGGGTGACGCGCTCGGAC
GCTCTGGTGGAATCGGAGGC

Downstream 100 bases:

>100_bases
GCCCCGGCGCACCTGCCGCCCCGGGCCTCCGGTGAGGCCACGCCCGGCTCCTCCCTAGGATGGAGCCCATGACGCAGCAG
CCGTTCTCGCGCCCTGGGGC

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MDLARALASLPANPRIVITGNHATPWHTLKLVDDALDDYRLWTLNGQPGLPDREGVVLETSFVGPAQRRNPRLSYVPSRL
SMVPSLFGKQLPPDAVVLHTTRPRDGKLSLGVEVNVLPAAIEAVRRNGGVVIAQVNDNMPWTFGDALIDLDLVDVLVDGD
EPMPVAPVSSIDAASAKIGELVAARVSDGSTLQAGIGAVPDATMHGLTDRSGLRVWTEMFSDSVLALEKVGALDRNIPIS
ASFLFGSPELLEWVDGNERVEMVRTEVTNSPARIARNPKMVSVNTALQVDLFGQANASRINARIHSGFGGQTDFIVGAMH
SAGGQAFIALRSWHPKADCSTVVPMVDEPITSFQMSAIVTEQGLATVFGNDQREQARQIIEHAAHPSVREELREEAVALG
LA

Sequences:

>Translated_402_residues
MDLARALASLPANPRIVITGNHATPWHTLKLVDDALDDYRLWTLNGQPGLPDREGVVLETSFVGPAQRRNPRLSYVPSRL
SMVPSLFGKQLPPDAVVLHTTRPRDGKLSLGVEVNVLPAAIEAVRRNGGVVIAQVNDNMPWTFGDALIDLDLVDVLVDGD
EPMPVAPVSSIDAASAKIGELVAARVSDGSTLQAGIGAVPDATMHGLTDRSGLRVWTEMFSDSVLALEKVGALDRNIPIS
ASFLFGSPELLEWVDGNERVEMVRTEVTNSPARIARNPKMVSVNTALQVDLFGQANASRINARIHSGFGGQTDFIVGAMH
SAGGQAFIALRSWHPKADCSTVVPMVDEPITSFQMSAIVTEQGLATVFGNDQREQARQIIEHAAHPSVREELREEAVALG
LA
>Mature_402_residues
MDLARALASLPANPRIVITGNHATPWHTLKLVDDALDDYRLWTLNGQPGLPDREGVVLETSFVGPAQRRNPRLSYVPSRL
SMVPSLFGKQLPPDAVVLHTTRPRDGKLSLGVEVNVLPAAIEAVRRNGGVVIAQVNDNMPWTFGDALIDLDLVDVLVDGD
EPMPVAPVSSIDAASAKIGELVAARVSDGSTLQAGIGAVPDATMHGLTDRSGLRVWTEMFSDSVLALEKVGALDRNIPIS
ASFLFGSPELLEWVDGNERVEMVRTEVTNSPARIARNPKMVSVNTALQVDLFGQANASRINARIHSGFGGQTDFIVGAMH
SAGGQAFIALRSWHPKADCSTVVPMVDEPITSFQMSAIVTEQGLATVFGNDQREQARQIIEHAAHPSVREELREEAVALG
LA

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=212, Percent_Identity=30.188679245283, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32563853, Length=427, Percent_Identity=33.0210772833724, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17538151, Length=422, Percent_Identity=31.9905213270142, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319456, Length=213, Percent_Identity=32.3943661971831, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21358615, Length=353, Percent_Identity=34.5609065155807, Blast_Score=188, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 43170; Mature: 43170

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLARALASLPANPRIVITGNHATPWHTLKLVDDALDDYRLWTLNGQPGLPDREGVVLET
CCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEE
SFVGPAQRRNPRLSYVPSRLSMVPSLFGKQLPPDAVVLHTTRPRDGKLSLGVEVNVLPAA
ECCCCHHHCCCCCEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEHHHH
IEAVRRNGGVVIAQVNDNMPWTFGDALIDLDLVDVLVDGDEPMPVAPVSSIDAASAKIGE
HHHHHCCCCEEEEEECCCCCEEECCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
LVAARVSDGSTLQAGIGAVPDATMHGLTDRSGLRVWTEMFSDSVLALEKVGALDRNIPIS
HHEEECCCCCEEECCCCCCCCHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCEE
ASFLFGSPELLEWVDGNERVEMVRTEVTNSPARIARNPKMVSVNTALQVDLFGQANASRI
EEEECCCHHHHHHCCCCCCEEEEEHHHCCCCHHHHCCCCEEEEEEEEEEEECCCCCCCEE
NARIHSGFGGQTDFIVGAMHSAGGQAFIALRSWHPKADCSTVVPMVDEPITSFQMSAIVT
EEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHEEC
EQGLATVFGNDQREQARQIIEHAAHPSVREELREEAVALGLA
CCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLARALASLPANPRIVITGNHATPWHTLKLVDDALDDYRLWTLNGQPGLPDREGVVLET
CCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEE
SFVGPAQRRNPRLSYVPSRLSMVPSLFGKQLPPDAVVLHTTRPRDGKLSLGVEVNVLPAA
ECCCCHHHCCCCCEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEEHHHH
IEAVRRNGGVVIAQVNDNMPWTFGDALIDLDLVDVLVDGDEPMPVAPVSSIDAASAKIGE
HHHHHCCCCEEEEEECCCCCEEECCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
LVAARVSDGSTLQAGIGAVPDATMHGLTDRSGLRVWTEMFSDSVLALEKVGALDRNIPIS
HHEEECCCCCEEECCCCCCCCHHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCEE
ASFLFGSPELLEWVDGNERVEMVRTEVTNSPARIARNPKMVSVNTALQVDLFGQANASRI
EEEECCCHHHHHHCCCCCCEEEEEHHHCCCCHHHHCCCCEEEEEEEEEEEECCCCCCCEE
NARIHSGFGGQTDFIVGAMHSAGGQAFIALRSWHPKADCSTVVPMVDEPITSFQMSAIVT
EEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHEEC
EQGLATVFGNDQREQARQIIEHAAHPSVREELREEAVALGLA
CCCCEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]