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The map label for this gene is yyaJ [H]

Identifier: 119716019

GI number: 119716019

Start: 1896989

End: 1898470

Strand: Direct

Name: yyaJ [H]

Synonym: Noca_1785

Alternate gene names: 119716019

Gene position: 1896989-1898470 (Clockwise)

Preceding gene: 119716018

Following gene: 119716020

Centisome position: 38.05

GC content: 67.68

Gene sequence:

>1482_bases
ATGGCAGTCGAAACCGGTCGGATCACCACCGACATCCCCGCGCGTCTGGACCGGCTCCCGTGGGCCCGGTGGCACTGGCT
GGTCGTGATCGGACTCGGCACGGTCTGGATCCTGGACGGCCTCGAGGTCACCATCGTCGGCTCGATGTCGGACGCCCTCA
AGCCCGACGGCACCGGCCTGGGCATGAACAACTTCGACATCGGCCTCGCGGGCTCGATGTACGTCGCCGGTGCCTGCCTC
GGCGCCCCCTTCTTCGGGCAGCTCACCGACCGGCTCGGCCGCAAGAAGCTGTTCATCGTCACGCTCGCGGTCTACACCGT
GGCCACCGTGCTGACGGCGTTCTCGATGAACCCGATGTGGTACTTCGCCTGCCGCTTCCTGACCGGTTGCGGCATCGGCG
GTGAGTACGCCGCGATCAACTCCGCCATCGACGAGCTGATCCCCGCGAAGTACCGCGGTCGCGTCGACATCGCCATCAAC
GGCTCGTTCTGGGTCGGTGCGGCCGGGGGCGCGCTGCTGACGATCCCGCTGCTCGACCCGACGATGATCGACCAGTCCTG
GGGCTGGCGGCTCGCCTTCGGCCTGGGCGCGATCCTCGCCGTCGGCATCCTGGTCGTCCGGCGCAACGTCCCGGAGAGCC
CGCGCTGGTTGTTCATCCACGGCCGCGAGGACGAGGCGGAGCAGATCGTCCGCGACATCGAACGCACCGTCTCCGAGGAG
TCCCACCACCAGCTGCACGACGTGCACGACACGATCACGGTGCGGCAGCGCACGTCGATCGGCATCGGCCTGATCGCGAG
GACGGTCTTCACCCTGTACCCGAAGCGGACGATCCTGTGCTTCTCGCTGTTCGTCGGGCAGGCGTTCTTGTACAACGCCT
TCTTCTTCACCTACGGCGACACCCTGACGACCTTCCTCGGCGTGGAGCAGACCGGCTACTACATCGCGGTGTTCGCGGCG
AGCAACTTCGCCGGGGCGCTGCTGCTGAGCCCGCTGTTCGACACCCTGGGCCGGGTCAAGATGATCACCGCGACCTACAT
CGGGTCCGGGGTCCTGCTCGCCGTGACCGGCTTCTACCTGGGCAGCTTCGACGCCACCACCCTCACGCTGATGGGCGCGA
TCATCTTCTTCATGGCCTCGGCCGGCGCGAGTGCGGCGTACCTCACCGCCAGCGAGGTGTTCCCGATGGAGACCCGGGCC
CTGTGCATCGCGTTCTTCTACGCGATCGGCACCGCGGCCGGCGGCATCTCCGGCCCGCTGTTCTTCGGCTGGCTGATCGA
GCAGGCCTCGGCGGACAAGGACATCACGCAGATCGCGGTCGGCTACTTCCTCGGCGCCGCGCTGATGATCATCGGTGGCA
TCGTCGAGGCGTTCCTGGGCGTCAAGGCGGAGGGCAAGTCGCTGGAGAGCATCGCCCAGCCGCTCACCGCCGAGGACACC
GACACCGGTAGCACCGGCTCCACGCAGCCACAGCACGCCTGA

Upstream 100 bases:

>100_bases
GGGGTCGTTCCTGGGCTGATGGTCCGACGTCGTGGTTGCGGTCCGCGCGTGGGCGGTGGGTCAGGAGTGACGGCCGTCAC
CGGTGGGTACGGCACCCGCC

Downstream 100 bases:

>100_bases
CTCAGCACACCCGATCCACCGCCCGGGTCGCTCCGGGCGGAGCAGAGGAGACACCCGATGCCGATGCCGCCGCCGAAGCC
GTCGACCGAGGGCAAGCGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MAVETGRITTDIPARLDRLPWARWHWLVVIGLGTVWILDGLEVTIVGSMSDALKPDGTGLGMNNFDIGLAGSMYVAGACL
GAPFFGQLTDRLGRKKLFIVTLAVYTVATVLTAFSMNPMWYFACRFLTGCGIGGEYAAINSAIDELIPAKYRGRVDIAIN
GSFWVGAAGGALLTIPLLDPTMIDQSWGWRLAFGLGAILAVGILVVRRNVPESPRWLFIHGREDEAEQIVRDIERTVSEE
SHHQLHDVHDTITVRQRTSIGIGLIARTVFTLYPKRTILCFSLFVGQAFLYNAFFFTYGDTLTTFLGVEQTGYYIAVFAA
SNFAGALLLSPLFDTLGRVKMITATYIGSGVLLAVTGFYLGSFDATTLTLMGAIIFFMASAGASAAYLTASEVFPMETRA
LCIAFFYAIGTAAGGISGPLFFGWLIEQASADKDITQIAVGYFLGAALMIIGGIVEAFLGVKAEGKSLESIAQPLTAEDT
DTGSTGSTQPQHA

Sequences:

>Translated_493_residues
MAVETGRITTDIPARLDRLPWARWHWLVVIGLGTVWILDGLEVTIVGSMSDALKPDGTGLGMNNFDIGLAGSMYVAGACL
GAPFFGQLTDRLGRKKLFIVTLAVYTVATVLTAFSMNPMWYFACRFLTGCGIGGEYAAINSAIDELIPAKYRGRVDIAIN
GSFWVGAAGGALLTIPLLDPTMIDQSWGWRLAFGLGAILAVGILVVRRNVPESPRWLFIHGREDEAEQIVRDIERTVSEE
SHHQLHDVHDTITVRQRTSIGIGLIARTVFTLYPKRTILCFSLFVGQAFLYNAFFFTYGDTLTTFLGVEQTGYYIAVFAA
SNFAGALLLSPLFDTLGRVKMITATYIGSGVLLAVTGFYLGSFDATTLTLMGAIIFFMASAGASAAYLTASEVFPMETRA
LCIAFFYAIGTAAGGISGPLFFGWLIEQASADKDITQIAVGYFLGAALMIIGGIVEAFLGVKAEGKSLESIAQPLTAEDT
DTGSTGSTQPQHA
>Mature_492_residues
AVETGRITTDIPARLDRLPWARWHWLVVIGLGTVWILDGLEVTIVGSMSDALKPDGTGLGMNNFDIGLAGSMYVAGACLG
APFFGQLTDRLGRKKLFIVTLAVYTVATVLTAFSMNPMWYFACRFLTGCGIGGEYAAINSAIDELIPAKYRGRVDIAING
SFWVGAAGGALLTIPLLDPTMIDQSWGWRLAFGLGAILAVGILVVRRNVPESPRWLFIHGREDEAEQIVRDIERTVSEES
HHQLHDVHDTITVRQRTSIGIGLIARTVFTLYPKRTILCFSLFVGQAFLYNAFFFTYGDTLTTFLGVEQTGYYIAVFAAS
NFAGALLLSPLFDTLGRVKMITATYIGSGVLLAVTGFYLGSFDATTLTLMGAIIFFMASAGASAAYLTASEVFPMETRAL
CIAFFYAIGTAAGGISGPLFFGWLIEQASADKDITQIAVGYFLGAALMIIGGIVEAFLGVKAEGKSLESIAQPLTAEDTD
TGSTGSTQPQHA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=407, Percent_Identity=21.8673218673219, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI7662270, Length=232, Percent_Identity=27.1551724137931, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI216548223, Length=270, Percent_Identity=26.2962962962963, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI73695465, Length=187, Percent_Identity=29.9465240641711, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788074, Length=427, Percent_Identity=28.8056206088993, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786229, Length=396, Percent_Identity=25, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082159, Length=423, Percent_Identity=26.0047281323877, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082404, Length=213, Percent_Identity=24.8826291079812, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789207, Length=185, Percent_Identity=26.4864864864865, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788068, Length=481, Percent_Identity=25.3638253638254, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082231, Length=172, Percent_Identity=23.2558139534884, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=475, Percent_Identity=23.5789473684211, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565976, Length=300, Percent_Identity=24, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17565978, Length=182, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320766, Length=375, Percent_Identity=25.0666666666667, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324400, Length=375, Percent_Identity=24.8, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322618, Length=369, Percent_Identity=24.6612466124661, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319956, Length=369, Percent_Identity=24.6612466124661, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323653, Length=372, Percent_Identity=25, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323512, Length=484, Percent_Identity=22.9338842975207, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321886, Length=371, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323110, Length=374, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319718, Length=188, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649618, Length=351, Percent_Identity=26.4957264957265, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640198, Length=256, Percent_Identity=27.34375, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640196, Length=256, Percent_Identity=27.34375, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640200, Length=256, Percent_Identity=27.34375, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52976; Mature: 52845

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVETGRITTDIPARLDRLPWARWHWLVVIGLGTVWILDGLEVTIVGSMSDALKPDGTGL
CCCCCCCCCCCCHHHHHHCCCHHHEEEEEEECCCEEEECCCEEEEEECCHHHCCCCCCCC
GMNNFDIGLAGSMYVAGACLGAPFFGQLTDRLGRKKLFIVTLAVYTVATVLTAFSMNPMW
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCHH
YFACRFLTGCGIGGEYAAINSAIDELIPAKYRGRVDIAINGSFWVGAAGGALLTIPLLDP
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCEEEEECCCC
TMIDQSWGWRLAFGLGAILAVGILVVRRNVPESPRWLFIHGREDEAEQIVRDIERTVSEE
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
SHHQLHDVHDTITVRQRTSIGIGLIARTVFTLYPKRTILCFSLFVGQAFLYNAFFFTYGD
HHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCH
TLTTFLGVEQTGYYIAVFAASNFAGALLLSPLFDTLGRVKMITATYIGSGVLLAVTGFYL
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEHHHHCCCHHHHHHHHHH
GSFDATTLTLMGAIIFFMASAGASAAYLTASEVFPMETRALCIAFFYAIGTAAGGISGPL
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHH
FFGWLIEQASADKDITQIAVGYFLGAALMIIGGIVEAFLGVKAEGKSLESIAQPLTAEDT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DTGSTGSTQPQHA
CCCCCCCCCCCCC
>Mature Secondary Structure 
AVETGRITTDIPARLDRLPWARWHWLVVIGLGTVWILDGLEVTIVGSMSDALKPDGTGL
CCCCCCCCCCCHHHHHHCCCHHHEEEEEEECCCEEEECCCEEEEEECCHHHCCCCCCCC
GMNNFDIGLAGSMYVAGACLGAPFFGQLTDRLGRKKLFIVTLAVYTVATVLTAFSMNPMW
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCHH
YFACRFLTGCGIGGEYAAINSAIDELIPAKYRGRVDIAINGSFWVGAAGGALLTIPLLDP
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCEEEEECCCC
TMIDQSWGWRLAFGLGAILAVGILVVRRNVPESPRWLFIHGREDEAEQIVRDIERTVSEE
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
SHHQLHDVHDTITVRQRTSIGIGLIARTVFTLYPKRTILCFSLFVGQAFLYNAFFFTYGD
HHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCH
TLTTFLGVEQTGYYIAVFAASNFAGALLLSPLFDTLGRVKMITATYIGSGVLLAVTGFYL
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEHHHHCCCHHHHHHHHHH
GSFDATTLTLMGAIIFFMASAGASAAYLTASEVFPMETRALCIAFFYAIGTAAGGISGPL
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHH
FFGWLIEQASADKDITQIAVGYFLGAALMIIGGIVEAFLGVKAEGKSLESIAQPLTAEDT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DTGSTGSTQPQHA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]