Click here to switch to the map view.

The map label for this gene is rho [H]

Identifier: 119715982

GI number: 119715982

Start: 1857894

End: 1859630

Strand: Direct

Name: rho [H]

Synonym: Noca_1747

Alternate gene names: 119715982

Gene position: 1857894-1859630 (Clockwise)

Preceding gene: 119715981

Following gene: 119715983

Centisome position: 37.26

GC content: 69.03

Gene sequence:

>1737_bases
ATGAAGAAGGCTCAGCTGGTCGAGGCGATCAAGGCCCACCAGAGCGGCGGCCGGCCGGCCAAGGAGCGCGGCGAGCAGCA
GCAGGCCCAGCAGGAGCGGAGCGAGCAGCAGCGGACCCAGCCGGAACAGGCCCCGCAGGAGCGGACCCAGCCGGAGCGAC
CGCAGCAGCAGCGGTCGGAGGAGCAGCCGCGGCGCGACCAGCGGCCCGACGAGGCCCAGCGGGACCAGCAGCGGGACCAG
CAGCGCGAGCGCAACCGCGGCCAGGGTCAGGGGAACCACGACCAGAAGCAGGACCAGAACAAGCAGGGCCAGCCCAAGCG
GCAGGACCAGAAGCAGGCCCAGAACAAGCAGGACCAGAAGCAGGACCAGGGCAAGCAGGACCAGAAGCAGGACCAGGGTC
ACCAGGATCAGGACCATCACGACCAGGGACACCAGGACCAGGGGCACCAGGACCAGGGCCGGGCGGGCGAGGACCAGGGT
GAGGGCAGTCGCCGCAACCGGCGGCGTCGCGGTCGCGACCGTGACCGTACCGGTCGGGGGGTCACCGGCGGTGGTCAGCG
CAACGAGCCGGACACCACGATCCTCGAGGACGACGTCCTGGTGCCGGCCGCGGGCATCCTCGACGTTCTCGACAACTACG
CGTTCGTGCGGACCAGCGGCTACCTCCCCGGCCCTGACGACGTGTACGTGTCGCTCTCGATGGTGCGCAAGTTCGGGCTG
CGCCGCGGCGACGCGCTCGTCGGGCAGGTGCGCCAGCCCCGGGAGGGCGAGCGCAAGGAGAAGTTCAACCCGATGGTCCG
CATCGACAGCGTCAACGGCGCCGATCCGGAGATCGCGAAGGGGCGGGTCGACTTCGCCAAGCTGACCCCGCTCTACCCCT
CCGAGCGGTTGCGGCTGGAGACCGAGCCGACGAACCTGATCGGTCGGGTCATCGACATCGCGGCCCCGATCGGCAAGGGC
CAGCGCGGCCTGATCGTGTCCCCGGCGAAGGCCGGCAAGACCATGATCATGCAGTCGATCGCGAACTCGATCACCACCAA
CAACCCCGAGTGCCACCTGATGGTGGTGCTGGTCGACGAGCGGCCCGAGGAGGTCACCGACTTCGAGCGCTCGGTCAAGG
GTGAGGTCATCTCCTCGACCTTCGACCGTCCGGCCAGCGACCACACGATGGTCGCCGAGCTCGCCATCGAGCGGGCCAAG
CGGCTGGTCGAGCTCGGCCACGACGTCGTCGTACTGCTCGACGGCATCACCCGGTTGGGGCGCGCCTACAACCTCGCGAT
GCCGGCGAGCGGCCGGATCCTCTCCGGTGGTGTGGACTCGGCCGCGCTCTACCCACCGAAGAAGTTCTTCGGTGCGGCGC
GCAACATCGAGAACGGCGGCTCGCTGACCATCCTCGCCACGGCCCTGATCGAGAGCGGCTCGAAGATGGACGAGGTGATC
TTCGAGGAGTTCAAGGGCACCGGGAACATGGAGATCCGGTTGCGCCGCGACCTTGCCGACAAGCGACTGTTCCCCGCGAT
CGACGCGGTCCAGTCCGGCACCCGCCGCGAGGAGCTCCTGATGAGCAAGGAGGAGCTGGCCATCGTCTGGAAGCTGCGCC
GGGTGCTCTCCGGGCTCGACGGCCAGCAGGCGCTCGAGCTCCTGCTGGAGCGGCTGAAGAAGTCCCAGACCAACATCGAG
TTCCTGATGCAGGTCCAGAAGACGACCCCGACCCCGACCGGCGGGCGCGAAGACTGA

Upstream 100 bases:

>100_bases
GGCGGCGCCCGCGAAGAAGCGCGGCGGCGGGCTCAGCTCGATGCTGCTGGCCGACCTCAAGGCGATGGCCGCAGGCATGG
GCATCTCGGGCGCCGGCTCG

Downstream 100 bases:

>100_bases
GAACAGCCGGCACGCGTGCCAACGCCGTCTTACGCTTTCGCTGGACGCGATGCCGGATAGGCTGCGCACGCACATGCCCG
AGGGAAGGGGACCTGAGTGG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MKKAQLVEAIKAHQSGGRPAKERGEQQQAQQERSEQQRTQPEQAPQERTQPERPQQQRSEEQPRRDQRPDEAQRDQQRDQ
QRERNRGQGQGNHDQKQDQNKQGQPKRQDQKQAQNKQDQKQDQGKQDQKQDQGHQDQDHHDQGHQDQGHQDQGRAGEDQG
EGSRRNRRRRGRDRDRTGRGVTGGGQRNEPDTTILEDDVLVPAAGILDVLDNYAFVRTSGYLPGPDDVYVSLSMVRKFGL
RRGDALVGQVRQPREGERKEKFNPMVRIDSVNGADPEIAKGRVDFAKLTPLYPSERLRLETEPTNLIGRVIDIAAPIGKG
QRGLIVSPAKAGKTMIMQSIANSITTNNPECHLMVVLVDERPEEVTDFERSVKGEVISSTFDRPASDHTMVAELAIERAK
RLVELGHDVVVLLDGITRLGRAYNLAMPASGRILSGGVDSAALYPPKKFFGAARNIENGGSLTILATALIESGSKMDEVI
FEEFKGTGNMEIRLRRDLADKRLFPAIDAVQSGTRREELLMSKEELAIVWKLRRVLSGLDGQQALELLLERLKKSQTNIE
FLMQVQKTTPTPTGGRED

Sequences:

>Translated_578_residues
MKKAQLVEAIKAHQSGGRPAKERGEQQQAQQERSEQQRTQPEQAPQERTQPERPQQQRSEEQPRRDQRPDEAQRDQQRDQ
QRERNRGQGQGNHDQKQDQNKQGQPKRQDQKQAQNKQDQKQDQGKQDQKQDQGHQDQDHHDQGHQDQGHQDQGRAGEDQG
EGSRRNRRRRGRDRDRTGRGVTGGGQRNEPDTTILEDDVLVPAAGILDVLDNYAFVRTSGYLPGPDDVYVSLSMVRKFGL
RRGDALVGQVRQPREGERKEKFNPMVRIDSVNGADPEIAKGRVDFAKLTPLYPSERLRLETEPTNLIGRVIDIAAPIGKG
QRGLIVSPAKAGKTMIMQSIANSITTNNPECHLMVVLVDERPEEVTDFERSVKGEVISSTFDRPASDHTMVAELAIERAK
RLVELGHDVVVLLDGITRLGRAYNLAMPASGRILSGGVDSAALYPPKKFFGAARNIENGGSLTILATALIESGSKMDEVI
FEEFKGTGNMEIRLRRDLADKRLFPAIDAVQSGTRREELLMSKEELAIVWKLRRVLSGLDGQQALELLLERLKKSQTNIE
FLMQVQKTTPTPTGGRED
>Mature_578_residues
MKKAQLVEAIKAHQSGGRPAKERGEQQQAQQERSEQQRTQPEQAPQERTQPERPQQQRSEEQPRRDQRPDEAQRDQQRDQ
QRERNRGQGQGNHDQKQDQNKQGQPKRQDQKQAQNKQDQKQDQGKQDQKQDQGHQDQDHHDQGHQDQGHQDQGRAGEDQG
EGSRRNRRRRGRDRDRTGRGVTGGGQRNEPDTTILEDDVLVPAAGILDVLDNYAFVRTSGYLPGPDDVYVSLSMVRKFGL
RRGDALVGQVRQPREGERKEKFNPMVRIDSVNGADPEIAKGRVDFAKLTPLYPSERLRLETEPTNLIGRVIDIAAPIGKG
QRGLIVSPAKAGKTMIMQSIANSITTNNPECHLMVVLVDERPEEVTDFERSVKGEVISSTFDRPASDHTMVAELAIERAK
RLVELGHDVVVLLDGITRLGRAYNLAMPASGRILSGGVDSAALYPPKKFFGAARNIENGGSLTILATALIESGSKMDEVI
FEEFKGTGNMEIRLRRDLADKRLFPAIDAVQSGTRREELLMSKEELAIVWKLRRVLSGLDGQQALELLLERLKKSQTNIE
FLMQVQKTTPTPTGGRED

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=372, Percent_Identity=55.6451612903226, Blast_Score=427, Evalue=1e-120,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 64930; Mature: 64930

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAQLVEAIKAHQSGGRPAKERGEQQQAQQERSEQQRTQPEQAPQERTQPERPQQQRSE
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCHHHCCCCCCHHHHHHH
EQPRRDQRPDEAQRDQQRDQQRERNRGQGQGNHDQKQDQNKQGQPKRQDQKQAQNKQDQK
HCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHH
QDQGKQDQKQDQGHQDQDHHDQGHQDQGHQDQGRAGEDQGEGSRRNRRRRGRDRDRTGRG
HHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
VTGGGQRNEPDTTILEDDVLVPAAGILDVLDNYAFVRTSGYLPGPDDVYVSLSMVRKFGL
CCCCCCCCCCCCCEECCCCCCCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCC
RRGDALVGQVRQPREGERKEKFNPMVRIDSVNGADPEIAKGRVDFAKLTPLYPSERLRLE
CCCCHHHHHCCCCCCCCHHHHCCCCEEEECCCCCCCHHHCCCCCHHHCCCCCCCCCEEEE
TEPTNLIGRVIDIAAPIGKGQRGLIVSPAKAGKTMIMQSIANSITTNNPECHLMVVLVDE
CCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
RPEEVTDFERSVKGEVISSTFDRPASDHTMVAELAIERAKRLVELGHDVVVLLDGITRLG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RAYNLAMPASGRILSGGVDSAALYPPKKFFGAARNIENGGSLTILATALIESGSKMDEVI
HHHEECCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHH
FEEFKGTGNMEIRLRRDLADKRLFPAIDAVQSGTRREELLMSKEELAIVWKLRRVLSGLD
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GQQALELLLERLKKSQTNIEFLMQVQKTTPTPTGGRED
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKAQLVEAIKAHQSGGRPAKERGEQQQAQQERSEQQRTQPEQAPQERTQPERPQQQRSE
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCHHHCCCCCCHHHHHHH
EQPRRDQRPDEAQRDQQRDQQRERNRGQGQGNHDQKQDQNKQGQPKRQDQKQAQNKQDQK
HCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHH
QDQGKQDQKQDQGHQDQDHHDQGHQDQGHQDQGRAGEDQGEGSRRNRRRRGRDRDRTGRG
HHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
VTGGGQRNEPDTTILEDDVLVPAAGILDVLDNYAFVRTSGYLPGPDDVYVSLSMVRKFGL
CCCCCCCCCCCCCEECCCCCCCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCC
RRGDALVGQVRQPREGERKEKFNPMVRIDSVNGADPEIAKGRVDFAKLTPLYPSERLRLE
CCCCHHHHHCCCCCCCCHHHHCCCCEEEECCCCCCCHHHCCCCCHHHCCCCCCCCCEEEE
TEPTNLIGRVIDIAAPIGKGQRGLIVSPAKAGKTMIMQSIANSITTNNPECHLMVVLVDE
CCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
RPEEVTDFERSVKGEVISSTFDRPASDHTMVAELAIERAKRLVELGHDVVVLLDGITRLG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RAYNLAMPASGRILSGGVDSAALYPPKKFFGAARNIENGGSLTILATALIESGSKMDEVI
HHHEECCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHH
FEEFKGTGNMEIRLRRDLADKRLFPAIDAVQSGTRREELLMSKEELAIVWKLRRVLSGLD
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GQQALELLLERLKKSQTNIEFLMQVQKTTPTPTGGRED
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8702978 [H]