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The map label for this gene is argS [H]

Identifier: 119715977

GI number: 119715977

Start: 1851047

End: 1852615

Strand: Direct

Name: argS [H]

Synonym: Noca_1742

Alternate gene names: 119715977

Gene position: 1851047-1852615 (Clockwise)

Preceding gene: 119715974

Following gene: 119715978

Centisome position: 37.13

GC content: 70.62

Gene sequence:

>1569_bases
GTGACGGTGGAGCGTCCGCGATCCAAGGAGCACGGCGACTACGCCACCAACGTCGCCCTCCAGCTGGGCAAGAAGGCCGG
GATGAACCCGCGCGACCTGGCCACGCTGGTCCAGCAGCGCCTGGAGCAGACCGACGGCATCGCCGGGGTCGACATCGCCG
GCCCGGGCTTCCTCAACATCACGGTCGCCGCCGGTGCCCAGGGCATCGTGGCGGCTGAGATCGTCGACGCCGGCGCGGCG
TACGGGCACACCGACGTGCTGCGCGGCGAGCGGGTCAACGTCGAGTTCATCTCGGCCAACCCGACCGGGCCGCTGCACCT
GGGCCACACCCGCTGGGCCGTCGTGGGCGACGCGATCTCCCGCGTGCTCGAGGCCGGCGGGGCCACCGTGACCCGCGAGT
TCTACATCAACGACCGCGGCAACCAGATGGACCTCTTCGGTGCGTCCATCGAGGCCGCCGCGCTCGGCAAGCCGACCCCC
GATGACGGTTACCACGGCGGCTACATCGCGGACCTCGCGCGGCAGATCGTCGCCGAGGACCCGGCGATCCTCGAGCTCCC
CGACGAGGAGCGCCTGGTCGCGTTCCGCGAGCAGGGCTACGCGCTCCAGCTCGCCCAGCAGCAGGAGCAGCTGGCCCGGT
TCAACACCGTCTTCGACGTGTGGTTCTCCGAGCGCAGCCTGCACGACAGCGATGACGTCGCGGCCGGGCTGGACAAGCTG
CGGGCGCAGGGGCACCTCTACGAGGACGACGGTGCCTTGTGGATGCGGACCACCGACTTCGGTGACGACAAGGACCGGGT
GCTGATCCGGTCGAACGGCGAGCTGACCTACTTCGCCAGCGATACCGCCTACTACGTGAACAAGCGCGAGCGCGGCTTCG
ACCGCTGCATCTACCTGCTCGGCGCCGACCACCACGGCTACGTCGGCCGGCTCAAGGCGATGGCCGCCTGCGCCGGGGAC
GACCCGGAGCGCAACATCGAGGTGCTGATCGGCCAGCTGGTCAAGATCGTCCGGGGCGGCGAGGAGGTGCGCCTCTCGAA
GCGGGCCGGCGAGATCGTCTCCCTCGAGGAGCTGATCGACGAGATCGGCACCGACGCGCTGCGCTACTCCCTCGCCCGCT
ACCCGGCCGACTCGCCGCTCACGCTGGACATCGCCGAGATCACCAAGCAGTCCAGCGAGAACCCGGTGTTCTACGTGCAG
TACGCCCACGCCCGGATCGCCTCGATCCTGCGCAACGCCGAGGACCTCGGCATCGCCTGGTCGACCGGTGACTTCGACCC
GGCGCTGCTGTCCCACCCCAAGGAGGGTGAGCTGCTGCGCGCGCTGGCGGAGTTCCCCCGGGTGGTCGCCGCCGCCGCGG
AGCTGCGCGAGCCGCACCGGGTGGCGCGCTACCTGGAGGACATGGCCGGTGTCTACCACCGGTTCTACGACAACTGCCGG
GTGCTGCCGATGGGCGATGAGCAAGCCGGTGACCTGCACCGCGCCCGGCTCGTGCTCGTCGCGGCCACCCGCACCGTCCT
GGCCAACGGCCTCGACCTGGTCGGGGTCTCCGCACCCGAGCGGATGTAG

Upstream 100 bases:

>100_bases
ACCGGTGACTCCAGAGCAGCTCTCCACCGCGATCGTCGACGTACTGACGACGCTGTCCGACGAGGGTGCGATCACCCTCC
CCGACGGCGTCCCTGCGAAC

Downstream 100 bases:

>100_bases
GACGGATGAGCCACGAAGCCGGCTGGGCGCACGCGCCCGGCGCCCTCCGCGGTCCCGCCTGGCTGCAGGCGCCCGCAGAT
CCGGACGCCCTGGTCTCGCA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MTVERPRSKEHGDYATNVALQLGKKAGMNPRDLATLVQQRLEQTDGIAGVDIAGPGFLNITVAAGAQGIVAAEIVDAGAA
YGHTDVLRGERVNVEFISANPTGPLHLGHTRWAVVGDAISRVLEAGGATVTREFYINDRGNQMDLFGASIEAAALGKPTP
DDGYHGGYIADLARQIVAEDPAILELPDEERLVAFREQGYALQLAQQQEQLARFNTVFDVWFSERSLHDSDDVAAGLDKL
RAQGHLYEDDGALWMRTTDFGDDKDRVLIRSNGELTYFASDTAYYVNKRERGFDRCIYLLGADHHGYVGRLKAMAACAGD
DPERNIEVLIGQLVKIVRGGEEVRLSKRAGEIVSLEELIDEIGTDALRYSLARYPADSPLTLDIAEITKQSSENPVFYVQ
YAHARIASILRNAEDLGIAWSTGDFDPALLSHPKEGELLRALAEFPRVVAAAAELREPHRVARYLEDMAGVYHRFYDNCR
VLPMGDEQAGDLHRARLVLVAATRTVLANGLDLVGVSAPERM

Sequences:

>Translated_522_residues
MTVERPRSKEHGDYATNVALQLGKKAGMNPRDLATLVQQRLEQTDGIAGVDIAGPGFLNITVAAGAQGIVAAEIVDAGAA
YGHTDVLRGERVNVEFISANPTGPLHLGHTRWAVVGDAISRVLEAGGATVTREFYINDRGNQMDLFGASIEAAALGKPTP
DDGYHGGYIADLARQIVAEDPAILELPDEERLVAFREQGYALQLAQQQEQLARFNTVFDVWFSERSLHDSDDVAAGLDKL
RAQGHLYEDDGALWMRTTDFGDDKDRVLIRSNGELTYFASDTAYYVNKRERGFDRCIYLLGADHHGYVGRLKAMAACAGD
DPERNIEVLIGQLVKIVRGGEEVRLSKRAGEIVSLEELIDEIGTDALRYSLARYPADSPLTLDIAEITKQSSENPVFYVQ
YAHARIASILRNAEDLGIAWSTGDFDPALLSHPKEGELLRALAEFPRVVAAAAELREPHRVARYLEDMAGVYHRFYDNCR
VLPMGDEQAGDLHRARLVLVAATRTVLANGLDLVGVSAPERM
>Mature_521_residues
TVERPRSKEHGDYATNVALQLGKKAGMNPRDLATLVQQRLEQTDGIAGVDIAGPGFLNITVAAGAQGIVAAEIVDAGAAY
GHTDVLRGERVNVEFISANPTGPLHLGHTRWAVVGDAISRVLEAGGATVTREFYINDRGNQMDLFGASIEAAALGKPTPD
DGYHGGYIADLARQIVAEDPAILELPDEERLVAFREQGYALQLAQQQEQLARFNTVFDVWFSERSLHDSDDVAAGLDKLR
AQGHLYEDDGALWMRTTDFGDDKDRVLIRSNGELTYFASDTAYYVNKRERGFDRCIYLLGADHHGYVGRLKAMAACAGDD
PERNIEVLIGQLVKIVRGGEEVRLSKRAGEIVSLEELIDEIGTDALRYSLARYPADSPLTLDIAEITKQSSENPVFYVQY
AHARIASILRNAEDLGIAWSTGDFDPALLSHPKEGELLRALAEFPRVVAAAAELREPHRVARYLEDMAGVYHRFYDNCRV
LPMGDEQAGDLHRARLVLVAATRTVLANGLDLVGVSAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=580, Percent_Identity=24.6551724137931, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1788184, Length=569, Percent_Identity=25.3075571177504, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320548, Length=553, Percent_Identity=25.3164556962025, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI18859963, Length=575, Percent_Identity=24.1739130434783, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571570, Length=548, Percent_Identity=24.4525547445255, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 57180; Mature: 57049

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVERPRSKEHGDYATNVALQLGKKAGMNPRDLATLVQQRLEQTDGIAGVDIAGPGFLNI
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEE
TVAAGAQGIVAAEIVDAGAAYGHTDVLRGERVNVEFISANPTGPLHLGHTRWAVVGDAIS
EEECCCCCEEEHHHHHCCCCCCCHHHCCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHH
RVLEAGGATVTREFYINDRGNQMDLFGASIEAAALGKPTPDDGYHGGYIADLARQIVAED
HHHHCCCCEEEEEEEECCCCCEEEEECCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
PAILELPDEERLVAFREQGYALQLAQQQEQLARFNTVFDVWFSERSLHDSDDVAAGLDKL
CCEEECCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RAQGHLYEDDGALWMRTTDFGDDKDRVLIRSNGELTYFASDTAYYVNKRERGFDRCIYLL
HHCCCEEECCCEEEEEECCCCCCCCEEEEEECCCEEEEECCCEEEECCCCCCCCCEEEEE
GADHHGYVGRLKAMAACAGDDPERNIEVLIGQLVKIVRGGEEVRLSKRAGEIVSLEELID
ECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHEEEHHHCCCEEEHHHHHH
EIGTDALRYSLARYPADSPLTLDIAEITKQSSENPVFYVQYAHARIASILRNAEDLGIAW
HHCCHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCCEEEEEEHHHHHHHHHHCHHHCCEEE
STGDFDPALLSHPKEGELLRALAEFPRVVAAAAELREPHRVARYLEDMAGVYHRFYDNCR
ECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCE
VLPMGDEQAGDLHRARLVLVAATRTVLANGLDLVGVSAPERM
EEECCCCCCCCHHHHEEEEEEHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure 
TVERPRSKEHGDYATNVALQLGKKAGMNPRDLATLVQQRLEQTDGIAGVDIAGPGFLNI
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEE
TVAAGAQGIVAAEIVDAGAAYGHTDVLRGERVNVEFISANPTGPLHLGHTRWAVVGDAIS
EEECCCCCEEEHHHHHCCCCCCCHHHCCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHH
RVLEAGGATVTREFYINDRGNQMDLFGASIEAAALGKPTPDDGYHGGYIADLARQIVAED
HHHHCCCCEEEEEEEECCCCCEEEEECCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
PAILELPDEERLVAFREQGYALQLAQQQEQLARFNTVFDVWFSERSLHDSDDVAAGLDKL
CCEEECCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RAQGHLYEDDGALWMRTTDFGDDKDRVLIRSNGELTYFASDTAYYVNKRERGFDRCIYLL
HHCCCEEECCCEEEEEECCCCCCCCEEEEEECCCEEEEECCCEEEECCCCCCCCCEEEEE
GADHHGYVGRLKAMAACAGDDPERNIEVLIGQLVKIVRGGEEVRLSKRAGEIVSLEELID
ECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHEEEHHHCCCEEEHHHHHH
EIGTDALRYSLARYPADSPLTLDIAEITKQSSENPVFYVQYAHARIASILRNAEDLGIAW
HHCCHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCCEEEEEEHHHHHHHHHHCHHHCCEEE
STGDFDPALLSHPKEGELLRALAEFPRVVAAAAELREPHRVARYLEDMAGVYHRFYDNCR
ECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCE
VLPMGDEQAGDLHRARLVLVAATRTVLANGLDLVGVSAPERM
EEECCCCCCCCHHHHEEEEEEHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA