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The map label for this gene is yogA [H]

Identifier: 119715963

GI number: 119715963

Start: 1836732

End: 1837709

Strand: Direct

Name: yogA [H]

Synonym: Noca_1728

Alternate gene names: 119715963

Gene position: 1836732-1837709 (Clockwise)

Preceding gene: 119715962

Following gene: 119715964

Centisome position: 36.84

GC content: 73.21

Gene sequence:

>978_bases
ATGTTCGCCGTCTACGCCGACCGGTTCTCCAAGGACGACCCGCTCTCCGCCCTGCAGGTGGGGGAGCGCCCGGATCCAGC
GGACTCGGGGATCCCCGACGGGTGGACCACGGTCACCGTGAAGGCCGCCTCGCTCAACCACCACGACCTGTTCTCGCTGC
GCGGGGTCGGGCTGCGCGAGGAGGCGCTGCCGATGATCCTCGGCTGCGACGCCGCCGGGTACGACGAGGACGGCAACGAG
GTCGTCGTCCACGCGGTGATCAGCGACCCGTCCTGGACCGGCGACGAGACCCTCGACCCGAAGCGGTCGCTGCTCTCCGA
GCGCTACCAGGGCACGTTCGCCGAGCGGGTCGCCGTACCCCGCCGCAACGTCGTCCCCAAGCCGGCCTCGCTGTCCTTCG
AGGAGGCCGCCTGCCTGCCGACCGCCTGGCTCACGGCCTACCGGATGCTGTTCACCCGCGGTGAGCTGCGCGCCGGCGAG
ACCGTCCTCGTGCAGGGCGCCGGGGGCGGCGTCGCGACCGCCGTGATCACCCTGGCCCGGGCGGCCGGGCTGCGCGTGCT
CGTGACCAGCCGCGACGAGTCCAAGCGCGCCCGCGCGCTCGAGCTCGGCGCGCACGAGGCCTTCGAGTCCGGAGCGCGGC
TGCCGGTCAAGGTCGACGCCGTCATGGAGACCGTCGGCAAGGCCACCTGGGCGCACTCCATCCGCTCACTGCGCCCGGGC
GGGCGCATCGTCACGTCCGGCACCACCTCCGGGCCGGACGTCGACGACGCCGAGCTCACCCGGATCTTCTTCCTCCAGCT
CAGCGTGGTCGGCTCGACGATGGGCACCCGCGCCGAGCTCGCCGCGCTGGTCTCCCTGCTCGACGCCTCGGGCGCGCGCC
CGCTGGTCGACCGCACGCTGCCGATGACCGAGGCCCGCGCCGGCTTCGCAGCGATGCTCGAGGGCGAGCAGTTCGGGAAG
ATCGTCTTCACCCGATGA

Upstream 100 bases:

>100_bases
CCGTTCGACCCCCGGGTCGGGCCGGCGGTGGCGGCGGCTGTGGCGGACGCCGCACGGCGCGACGGGGTGGCCCGCCGGTA
GGGACGGGTAGGTTCGGACA

Downstream 100 bases:

>100_bases
TCCACCTCCTCACCGGGGCCGGGTCGGGCATCGGCGCGGAGCTGGCCCGCCGGCTGCACGAGCGCGGCGACGACCTGGTC
CTGCTGGCGCGCTCACCGGA

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MFAVYADRFSKDDPLSALQVGERPDPADSGIPDGWTTVTVKAASLNHHDLFSLRGVGLREEALPMILGCDAAGYDEDGNE
VVVHAVISDPSWTGDETLDPKRSLLSERYQGTFAERVAVPRRNVVPKPASLSFEEAACLPTAWLTAYRMLFTRGELRAGE
TVLVQGAGGGVATAVITLARAAGLRVLVTSRDESKRARALELGAHEAFESGARLPVKVDAVMETVGKATWAHSIRSLRPG
GRIVTSGTTSGPDVDDAELTRIFFLQLSVVGSTMGTRAELAALVSLLDASGARPLVDRTLPMTEARAGFAAMLEGEQFGK
IVFTR

Sequences:

>Translated_325_residues
MFAVYADRFSKDDPLSALQVGERPDPADSGIPDGWTTVTVKAASLNHHDLFSLRGVGLREEALPMILGCDAAGYDEDGNE
VVVHAVISDPSWTGDETLDPKRSLLSERYQGTFAERVAVPRRNVVPKPASLSFEEAACLPTAWLTAYRMLFTRGELRAGE
TVLVQGAGGGVATAVITLARAAGLRVLVTSRDESKRARALELGAHEAFESGARLPVKVDAVMETVGKATWAHSIRSLRPG
GRIVTSGTTSGPDVDDAELTRIFFLQLSVVGSTMGTRAELAALVSLLDASGARPLVDRTLPMTEARAGFAAMLEGEQFGK
IVFTR
>Mature_325_residues
MFAVYADRFSKDDPLSALQVGERPDPADSGIPDGWTTVTVKAASLNHHDLFSLRGVGLREEALPMILGCDAAGYDEDGNE
VVVHAVISDPSWTGDETLDPKRSLLSERYQGTFAERVAVPRRNVVPKPASLSFEEAACLPTAWLTAYRMLFTRGELRAGE
TVLVQGAGGGVATAVITLARAAGLRVLVTSRDESKRARALELGAHEAFESGARLPVKVDAVMETVGKATWAHSIRSLRPG
GRIVTSGTTSGPDVDDAELTRIFFLQLSVVGSTMGTRAELAALVSLLDASGARPLVDRTLPMTEARAGFAAMLEGEQFGK
IVFTR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=347, Percent_Identity=27.9538904899135, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI22538444, Length=347, Percent_Identity=27.9538904899135, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI18379349, Length=322, Percent_Identity=27.9503105590062, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI194239674, Length=310, Percent_Identity=26.1290322580645, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI13236495, Length=310, Percent_Identity=26.1290322580645, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI194239676, Length=188, Percent_Identity=32.4468085106383, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI47519420, Length=331, Percent_Identity=26.8882175226586, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=272, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221330659, Length=318, Percent_Identity=25.4716981132075, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920632, Length=318, Percent_Identity=25.4716981132075, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581345, Length=349, Percent_Identity=26.3610315186246, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 34680; Mature: 34680

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAVYADRFSKDDPLSALQVGERPDPADSGIPDGWTTVTVKAASLNHHDLFSLRGVGLRE
CEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHCCCCCCH
EALPMILGCDAAGYDEDGNEVVVHAVISDPSWTGDETLDPKRSLLSERYQGTFAERVAVP
HCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCC
RRNVVPKPASLSFEEAACLPTAWLTAYRMLFTRGELRAGETVLVQGAGGGVATAVITLAR
CCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHH
AAGLRVLVTSRDESKRARALELGAHEAFESGARLPVKVDAVMETVGKATWAHSIRSLRPG
HCCEEEEEECCCCHHHHHHHHHCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
GRIVTSGTTSGPDVDDAELTRIFFLQLSVVGSTMGTRAELAALVSLLDASGARPLVDRTL
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHCCC
PMTEARAGFAAMLEGEQFGKIVFTR
CCHHHHCCHHEEECCCCCCCEEECC
>Mature Secondary Structure
MFAVYADRFSKDDPLSALQVGERPDPADSGIPDGWTTVTVKAASLNHHDLFSLRGVGLRE
CEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHCCCCCCH
EALPMILGCDAAGYDEDGNEVVVHAVISDPSWTGDETLDPKRSLLSERYQGTFAERVAVP
HCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCC
RRNVVPKPASLSFEEAACLPTAWLTAYRMLFTRGELRAGETVLVQGAGGGVATAVITLAR
CCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHH
AAGLRVLVTSRDESKRARALELGAHEAFESGARLPVKVDAVMETVGKATWAHSIRSLRPG
HCCEEEEEECCCCHHHHHHHHHCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
GRIVTSGTTSGPDVDDAELTRIFFLQLSVVGSTMGTRAELAALVSLLDASGARPLVDRTL
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHCCC
PMTEARAGFAAMLEGEQFGKIVFTR
CCHHHHCCHHEEECCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]