BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is ucpA [C]

Identifier: 119715964

GI number: 119715964

Start: 1837706

End: 1838389

Strand: Direct

Name: ucpA [C]

Synonym: Noca_1729

Alternate gene names: 119715964

Gene position: 1837706-1838389 (Clockwise)

Preceding gene: 119715963

Following gene: 119715966

Centisome position: 36.86

GC content: 76.02

Gene sequence:

>684_bases
ATGATCCACCTCCTCACCGGGGCCGGGTCGGGCATCGGCGCGGAGCTGGCCCGCCGGCTGCACGAGCGCGGCGACGACCT
GGTCCTGCTGGCGCGCTCACCGGAGCGGGCGGCGGAGCTGCGCACGGCCTACGCCGGCGCGACGGTCCTCGTGGCCGACC
TGGCCCGGCCGGAGTCCGTGGAGTCGCTCGACCTGCCCGACGGACTGGACTCGGTGGTGCACGCGGCCGGGGTCGTCGAG
CTGGGCGCCGTGGCCGCGCTCTCGGTGGCGGACTGGACCTCGCAGCTGCGGGTCAACCTGGTCGCGCCCGCCGCGCTGAC
CCGGGTGGCACTCCCCGCGCTGCGTGCCCGCCGCGGCACCGTGGTCTTCGTCAACTCCAGTGCCGGGCGGACCGCCCACC
CGTCGTGGTCGGCGTACGCCGCCTCCAAGCACGGGCTGCGCGCCCTCGCGGACGCACTGCGCGCCGAGGAGGCGGAGCAC
GGCGTCCGCGTGAGCACCGTCTTCCCGGGTCGCACGGCCACGCCGATGCAGGAGAAGGTGCACCGGCAGGAGGGCAGGGA
GTACGACGCCGCCCGGTGGGTCCGGCCCGAGACCGTCGCCGACACGATCCTGCACGTGCTCGACCTGCCGGCCGACGCGA
CGATCCCGGAAGTGGTGGTCAGGCCGGGCCCGAGCGCCAGTTGA

Upstream 100 bases:

>100_bases
CGCGCCCGCTGGTCGACCGCACGCTGCCGATGACCGAGGCCCGCGCCGGCTTCGCAGCGATGCTCGAGGGCGAGCAGTTC
GGGAAGATCGTCTTCACCCG

Downstream 100 bases:

>100_bases
GGGCGCCGATCAGCACCATCCGCAGCTGCACCCGCGCCTGCTCGACGAGCGCCTGCTCGGCGGCCGGGCCGTCGGCCGTC
AGGATCGCTTCGGCGGTGGA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MIHLLTGAGSGIGAELARRLHERGDDLVLLARSPERAAELRTAYAGATVLVADLARPESVESLDLPDGLDSVVHAAGVVE
LGAVAALSVADWTSQLRVNLVAPAALTRVALPALRARRGTVVFVNSSAGRTAHPSWSAYAASKHGLRALADALRAEEAEH
GVRVSTVFPGRTATPMQEKVHRQEGREYDAARWVRPETVADTILHVLDLPADATIPEVVVRPGPSAS

Sequences:

>Translated_227_residues
MIHLLTGAGSGIGAELARRLHERGDDLVLLARSPERAAELRTAYAGATVLVADLARPESVESLDLPDGLDSVVHAAGVVE
LGAVAALSVADWTSQLRVNLVAPAALTRVALPALRARRGTVVFVNSSAGRTAHPSWSAYAASKHGLRALADALRAEEAEH
GVRVSTVFPGRTATPMQEKVHRQEGREYDAARWVRPETVADTILHVLDLPADATIPEVVVRPGPSAS
>Mature_227_residues
MIHLLTGAGSGIGAELARRLHERGDDLVLLARSPERAAELRTAYAGATVLVADLARPESVESLDLPDGLDSVVHAAGVVE
LGAVAALSVADWTSQLRVNLVAPAALTRVALPALRARRGTVVFVNSSAGRTAHPSWSAYAASKHGLRALADALRAEEAEH
GVRVSTVFPGRTATPMQEKVHRQEGREYDAARWVRPETVADTILHVLDLPADATIPEVVVRPGPSAS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=29.8755186721992, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=30.3482587064677, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI119392083, Length=196, Percent_Identity=35.7142857142857, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI157739938, Length=181, Percent_Identity=32.5966850828729, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI44680136, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI44680133, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI17738292, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503817, Length=221, Percent_Identity=26.2443438914027, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI50726952, Length=182, Percent_Identity=34.0659340659341, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI19743808, Length=191, Percent_Identity=32.9842931937173, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI22507405, Length=190, Percent_Identity=32.1052631578947, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5031737, Length=193, Percent_Identity=31.0880829015544, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=27.5720164609054, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=31.1881188118812, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.2169312169312, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI150247226, Length=189, Percent_Identity=31.2169312169312, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=34.5360824742268, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786701, Length=217, Percent_Identity=32.7188940092166, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1786812, Length=239, Percent_Identity=31.7991631799163, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1787526, Length=192, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787820, Length=238, Percent_Identity=28.1512605042017, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787335, Length=184, Percent_Identity=28.804347826087, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=163, Percent_Identity=31.9018404907975, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=227, Percent_Identity=30.3964757709251, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=200, Percent_Identity=29.5, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=191, Percent_Identity=30.8900523560209, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=205, Percent_Identity=29.2682926829268, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=226, Percent_Identity=30.9734513274336, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24644339, Length=184, Percent_Identity=33.1521739130435, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=220, Percent_Identity=30.9090909090909, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=30.9278350515464, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356301, Length=227, Percent_Identity=27.3127753303965, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28571387, Length=240, Percent_Identity=25.8333333333333, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=192, Percent_Identity=31.7708333333333, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28574402, Length=192, Percent_Identity=31.7708333333333, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24651139, Length=207, Percent_Identity=28.5024154589372, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641232, Length=240, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357041, Length=186, Percent_Identity=30.1075268817204, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648693, Length=255, Percent_Identity=26.2745098039216, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355889, Length=255, Percent_Identity=26.2745098039216, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007234, Length=242, Percent_Identity=27.6859504132231, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641388, Length=242, Percent_Identity=27.6859504132231, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=176, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281364494, Length=241, Percent_Identity=26.9709543568465, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639444, Length=225, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23954; Mature: 23954

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHLLTGAGSGIGAELARRLHERGDDLVLLARSPERAAELRTAYAGATVLVADLARPESV
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCHHHEEEHHCCCCCC
ESLDLPDGLDSVVHAAGVVELGAVAALSVADWTSQLRVNLVAPAALTRVALPALRARRGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHCCCCE
VVFVNSSAGRTAHPSWSAYAASKHGLRALADALRAEEAEHGVRVSTVFPGRTATPMQEKV
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHH
HRQEGREYDAARWVRPETVADTILHVLDLPADATIPEVVVRPGPSAS
HHHCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MIHLLTGAGSGIGAELARRLHERGDDLVLLARSPERAAELRTAYAGATVLVADLARPESV
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCHHHEEEHHCCCCCC
ESLDLPDGLDSVVHAAGVVELGAVAALSVADWTSQLRVNLVAPAALTRVALPALRARRGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHCCCCE
VVFVNSSAGRTAHPSWSAYAASKHGLRALADALRAEEAEHGVRVSTVFPGRTATPMQEKV
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHH
HRQEGREYDAARWVRPETVADTILHVLDLPADATIPEVVVRPGPSAS
HHHCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]