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The map label for this gene is lip2 [H]

Identifier: 119715889

GI number: 119715889

Start: 1756107

End: 1757177

Strand: Reverse

Name: lip2 [H]

Synonym: Noca_1654

Alternate gene names: 119715889

Gene position: 1757177-1756107 (Counterclockwise)

Preceding gene: 119715890

Following gene: 119715888

Centisome position: 35.24

GC content: 74.51

Gene sequence:

>1071_bases
ATGAGCCCCGCGCCCCACCCGCTCCAGGAGCGGATCGCGCGCCGCGTGATGCGCACCGTCGGCGCCCTGCCGGCGCCGGT
GCAGCGCGCGTTCGCCGGCCGTCCGATCCGGATCGACGGCCAGCAGCTGCACCCCGAGGTGCAGCTCGCCCTCCGGCTGC
TGCACCTGGCCGGCGGACCGACCTTCGAGACCCTGCCGCTCGCCGAGGGACGTGCCCAGATCAGCAGCGAGGCCTGGGTC
TTCGGGGACGAGCTCCCGGTCGAGACGGTGCGGGACCTCACCCTGGACGGTCGCAACGGCCCGATCCCGGCCCGGCTCTA
CCTCCCCTCGGGGCGGAGCGACCCGGCTGCACTGTTGGTGTACTTCCACGGCGGCGGCTGGGTCCTCGGCGGGCTCGACG
CGTCCGACTCCGCGTGCCGCTTCCTGGCCGACCATGCCGGGATCGCCGTCTTGTCGGTGGACTACCGCCTGGCACCGGAG
CATCGGTTCCCGGCGGCGGTCGAGGATGCCGTCGACGCCTTCCACGCTGCCGTCGCGGCGGCCACGACCTGGGGGGTCGA
CCCCGCCGCCATCGGCGTCGGCGGCGAGAGCGCCGGCGGGAACCTCGCCGCCGTGGTGGCGCAGCTGACGCACGCCGCTT
CCGGACCGGAGCCGGCCTGCCAGCTGCTGTTCTTCCCCGTCACGGACCTCTCCACCAAGCACCCGTCCTACGCACTGTTC
TCCGAGGGCTACTTCCTCACCGAGGCGCAGATGGAGTGGTACCGCGGCCACTACCTGGAGGATCCCGCGCAGGCGCTGGA
CCCGCGCGTGTCGCCGCTGCTCGCCGAGGACCTCTCGGGACTGTGCCCGGCCTACGTCGCCGTCGCCGGCTTCGACCCGC
TCCGCGATGAGGGCGCGGCCTACGCGCACCGGTTGCAGGAGGCCGGCGTCCGCGTCTCGCTGCAGCGGCACAGCGGCCTG
ATCCACGGGATCGTGAACGCCACCGGCGTGGGTCGGTCCGGGCGGGAGGTACTCCTCCAGGCGGCCGGGGCGCTCCGGAT
CGAGCTCGGCGCCCGCGCCGGGTCGGGCTGA

Upstream 100 bases:

>100_bases
CGCGGCGCGCGGTCTACGACCGCCAGTACCGCACGTTCACCCGGATCTACCGGCGCAACCGTCGCCTGTACGCCGCCCAC
AACCGCCCCAGGAGGAACCG

Downstream 100 bases:

>100_bases
ATCGCCACTCCGTCTAGAAAAGACCGAACAATGTTGTAGATCACGCAAAAGGACGCGGGTTCGGCTGCGCCGCGGCCACC
CCGGGAATAGCGTGGATCGA

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSPAPHPLQERIARRVMRTVGALPAPVQRAFAGRPIRIDGQQLHPEVQLALRLLHLAGGPTFETLPLAEGRAQISSEAWV
FGDELPVETVRDLTLDGRNGPIPARLYLPSGRSDPAALLVYFHGGGWVLGGLDASDSACRFLADHAGIAVLSVDYRLAPE
HRFPAAVEDAVDAFHAAVAAATTWGVDPAAIGVGGESAGGNLAAVVAQLTHAASGPEPACQLLFFPVTDLSTKHPSYALF
SEGYFLTEAQMEWYRGHYLEDPAQALDPRVSPLLAEDLSGLCPAYVAVAGFDPLRDEGAAYAHRLQEAGVRVSLQRHSGL
IHGIVNATGVGRSGREVLLQAAGALRIELGARAGSG

Sequences:

>Translated_356_residues
MSPAPHPLQERIARRVMRTVGALPAPVQRAFAGRPIRIDGQQLHPEVQLALRLLHLAGGPTFETLPLAEGRAQISSEAWV
FGDELPVETVRDLTLDGRNGPIPARLYLPSGRSDPAALLVYFHGGGWVLGGLDASDSACRFLADHAGIAVLSVDYRLAPE
HRFPAAVEDAVDAFHAAVAAATTWGVDPAAIGVGGESAGGNLAAVVAQLTHAASGPEPACQLLFFPVTDLSTKHPSYALF
SEGYFLTEAQMEWYRGHYLEDPAQALDPRVSPLLAEDLSGLCPAYVAVAGFDPLRDEGAAYAHRLQEAGVRVSLQRHSGL
IHGIVNATGVGRSGREVLLQAAGALRIELGARAGSG
>Mature_355_residues
SPAPHPLQERIARRVMRTVGALPAPVQRAFAGRPIRIDGQQLHPEVQLALRLLHLAGGPTFETLPLAEGRAQISSEAWVF
GDELPVETVRDLTLDGRNGPIPARLYLPSGRSDPAALLVYFHGGGWVLGGLDASDSACRFLADHAGIAVLSVDYRLAPEH
RFPAAVEDAVDAFHAAVAAATTWGVDPAAIGVGGESAGGNLAAVVAQLTHAASGPEPACQLLFFPVTDLSTKHPSYALFS
EGYFLTEAQMEWYRGHYLEDPAQALDPRVSPLLAEDLSGLCPAYVAVAGFDPLRDEGAAYAHRLQEAGVRVSLQRHSGLI
HGIVNATGVGRSGREVLLQAAGALRIELGARAGSG

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI68299767, Length=320, Percent_Identity=29.6875, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI206597554, Length=284, Percent_Identity=30.9859154929577, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI157041239, Length=298, Percent_Identity=27.8523489932886, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI61966717, Length=344, Percent_Identity=27.906976744186, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI68051721, Length=277, Percent_Identity=27.4368231046931, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI226423947, Length=285, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786682, Length=286, Percent_Identity=27.6223776223776, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17567059, Length=269, Percent_Identity=30.1115241635688, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71996133, Length=308, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540028, Length=144, Percent_Identity=34.0277777777778, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI72001146, Length=130, Percent_Identity=35.3846153846154, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 37550; Mature: 37419

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAPHPLQERIARRVMRTVGALPAPVQRAFAGRPIRIDGQQLHPEVQLALRLLHLAGGP
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEECCHHHCHHHHHHHHHHHHCCCC
TFETLPLAEGRAQISSEAWVFGDELPVETVRDLTLDGRNGPIPARLYLPSGRSDPAALLV
CEEEECCCCCHHHHCCCCEEECCCCCHHHHHHCEECCCCCCCCEEEECCCCCCCCEEEEE
YFHGGGWVLGGLDASDSACRFLADHAGIAVLSVDYRLAPEHRFPAAVEDAVDAFHAAVAA
EEECCCEEEECCCCCCHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
ATTWGVDPAAIGVGGESAGGNLAAVVAQLTHAASGPEPACQLLFFPVTDLSTKHPSYALF
HHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEE
SEGYFLTEAQMEWYRGHYLEDPAQALDPRVSPLLAEDLSGLCPAYVAVAGFDPLRDEGAA
CCCEEEEHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCCCHHHCHHH
YAHRLQEAGVRVSLQRHSGLIHGIVNATGVGRSGREVLLQAAGALRIELGARAGSG
HHHHHHHCCCEEEEHHHCCEEEEHHHCCCCCCCHHHHHHHHCCEEEEEECCCCCCC
>Mature Secondary Structure 
SPAPHPLQERIARRVMRTVGALPAPVQRAFAGRPIRIDGQQLHPEVQLALRLLHLAGGP
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEECCHHHCHHHHHHHHHHHHCCCC
TFETLPLAEGRAQISSEAWVFGDELPVETVRDLTLDGRNGPIPARLYLPSGRSDPAALLV
CEEEECCCCCHHHHCCCCEEECCCCCHHHHHHCEECCCCCCCCEEEECCCCCCCCEEEEE
YFHGGGWVLGGLDASDSACRFLADHAGIAVLSVDYRLAPEHRFPAAVEDAVDAFHAAVAA
EEECCCEEEECCCCCCHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
ATTWGVDPAAIGVGGESAGGNLAAVVAQLTHAASGPEPACQLLFFPVTDLSTKHPSYALF
HHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEE
SEGYFLTEAQMEWYRGHYLEDPAQALDPRVSPLLAEDLSGLCPAYVAVAGFDPLRDEGAA
CCCEEEEHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCCCHHHCHHH
YAHRLQEAGVRVSLQRHSGLIHGIVNATGVGRSGREVLLQAAGALRIELGARAGSG
HHHHHHHCCCEEEEHHHCCEEEEHHHCCCCCCCHHHHHHHHCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]