Click here to switch to the map view.

The map label for this gene is mop [H]

Identifier: 119715871

GI number: 119715871

Start: 1738566

End: 1740038

Strand: Direct

Name: mop [H]

Synonym: Noca_1636

Alternate gene names: 119715871

Gene position: 1738566-1740038 (Clockwise)

Preceding gene: 119715870

Following gene: 119715872

Centisome position: 34.87

GC content: 76.04

Gene sequence:

>1473_bases
ATGGCAGCAGCACCCAGCATCCCCGGTGTCACCGTCAACGGCCGCCGCCTGTCCCTCGCCGGGGTGTCGCCGCACACCAC
GACGCTGGACCTGCTGCGCGGCGTCGGGCTCACCGGCGCCAAGGAGGGCTGCGCCGAGGGGGAGTGCGGCGCCTGCTCGG
TGCTGGTCGCTCGCCCCGACGGCGAGGGCATCCGGTGGACCGCGCTCAACGCGTGCCTGGTCCCGGCGGCCGCGCTCGAC
GGCCAGGAGCTGGTCACGGCCGAGGGCCTCGGCACGCCCGAGGACCTGCACCCGGTCCAGCACGAGATGGCGGTCCGCGG
CGGCTCGCAGTGCGGATACTGCACGCCGGGCTTCGTGTGCAGCATGGCCGCGGAGTTCTACCGGCCCGAGCGGGTCGCGA
CGGGCCCGGGTCCGTCCGGCGACGCGCACGAGCGGGGTCCCAACGGGTTCGACCTGGCCGCGCTGAGCGGCAACCTGTGC
CGCTGCACGGGCTACCGACCGATCCGGGACGCGGCGTACGCCCTGGGCTCCCCGGCTCCCGACGACCCGCTCGCGGCCCG
GGTTCACCGAGCCGCGCCGGCGCTGGAAGCCACCCGGCTCGAGGACGGGACCGGGGTGTTCGTGCGTCCGCGGGACCTCG
CCGAGGCGCTGGCCCTGCTGGGTGAGCACCCCGAGGCGGTGCCGGTCGCCGGCTGCACCGACTGGGGTGTCGAGGTGAAC
CTCCGCGGCGCGCGGGCGCCGTACGTCGTCGCCGTCGACCGGCTCCCCGAGCTGCGGCGGGTGTCGCTCCCTGCCCCGTC
CGGCGGCGCCTTCGAGATCGGCGCCGCGCTCTCGCTCTCCGAGGTCGAGCTCGCCCTGGCCGGCCGGGTGCCGCTCCTGG
CCGCGGTGTTCCCGCTGTTCGCCTCCCGGCTGATCCGCAACGGCGCCACGATCGGCGGCAACCTGGCGACCGCCTCGCCC
ATCGGCGACCTCGCACCCGCCCTGCTCGCCCTCGAGGCGTCCGTGGTGCTCGTCTCGACCGACGGGGACCGCGAGCTGCC
GATCGCGGAGCTCTTCACCGGCTACCGACGCTCGCAGCTGCGGCCGGGGGAGCTGATCCGAGCGGTGCGGATCCCACAGC
CGCTGGCCGGCACCACCGCCTTCCACAAGATCGCCAAGCGCCGGTACGACGACATCTCCAGCGTCGCGGTCGCCTTCGCC
CTCGACGTCGTCGACGAGACGGTCGTCCGGGCCAAGGTCGGCCTCGGCGGCGTGGCGGCCACGCCGATCCGCGCGCGGGC
GACCGAGGCCGCGCTCGAGGGCCGGACCTGGTCGGCCGAGACGGCACGCGCGGCCGCCGCGGTCCTGGGTGGAGAGGGGA
CGCCGATGGACGACCACCGGGCGAGCGCCGCCTACCGCGCCGCGATGCTCGAGCAGTCGCTGCTCAGGCTCTGGGCCCAG
GGCCCGTCGGACGAGGGTGAGGCGTCGGCATGA

Upstream 100 bases:

>100_bases
TCCACTGACGTCGGCCGCGGCGACCGGCCGCCCGGAACGTGCTCGCGGAGGCCGCCGGCCACGTAAAATGTTGTCGCGTT
GCGTGCGTGAGGAGAGCGGC

Downstream 100 bases:

>100_bases
GTGACCTGTCCACGCGCCCGGCCGACGGCGTCGTCGGCCGCGAGGTGCCGCACGAGGGCGCGGCCCTCCACGTCACCGGC
ACGGCGCTGTACACCGACGA

Product: molybdopterin dehydrogenase

Products: NA

Alternate protein names: Molybdenum iron sulfur protein [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MAAAPSIPGVTVNGRRLSLAGVSPHTTTLDLLRGVGLTGAKEGCAEGECGACSVLVARPDGEGIRWTALNACLVPAAALD
GQELVTAEGLGTPEDLHPVQHEMAVRGGSQCGYCTPGFVCSMAAEFYRPERVATGPGPSGDAHERGPNGFDLAALSGNLC
RCTGYRPIRDAAYALGSPAPDDPLAARVHRAAPALEATRLEDGTGVFVRPRDLAEALALLGEHPEAVPVAGCTDWGVEVN
LRGARAPYVVAVDRLPELRRVSLPAPSGGAFEIGAALSLSEVELALAGRVPLLAAVFPLFASRLIRNGATIGGNLATASP
IGDLAPALLALEASVVLVSTDGDRELPIAELFTGYRRSQLRPGELIRAVRIPQPLAGTTAFHKIAKRRYDDISSVAVAFA
LDVVDETVVRAKVGLGGVAATPIRARATEAALEGRTWSAETARAAAAVLGGEGTPMDDHRASAAYRAAMLEQSLLRLWAQ
GPSDEGEASA

Sequences:

>Translated_490_residues
MAAAPSIPGVTVNGRRLSLAGVSPHTTTLDLLRGVGLTGAKEGCAEGECGACSVLVARPDGEGIRWTALNACLVPAAALD
GQELVTAEGLGTPEDLHPVQHEMAVRGGSQCGYCTPGFVCSMAAEFYRPERVATGPGPSGDAHERGPNGFDLAALSGNLC
RCTGYRPIRDAAYALGSPAPDDPLAARVHRAAPALEATRLEDGTGVFVRPRDLAEALALLGEHPEAVPVAGCTDWGVEVN
LRGARAPYVVAVDRLPELRRVSLPAPSGGAFEIGAALSLSEVELALAGRVPLLAAVFPLFASRLIRNGATIGGNLATASP
IGDLAPALLALEASVVLVSTDGDRELPIAELFTGYRRSQLRPGELIRAVRIPQPLAGTTAFHKIAKRRYDDISSVAVAFA
LDVVDETVVRAKVGLGGVAATPIRARATEAALEGRTWSAETARAAAAVLGGEGTPMDDHRASAAYRAAMLEQSLLRLWAQ
GPSDEGEASA
>Mature_489_residues
AAAPSIPGVTVNGRRLSLAGVSPHTTTLDLLRGVGLTGAKEGCAEGECGACSVLVARPDGEGIRWTALNACLVPAAALDG
QELVTAEGLGTPEDLHPVQHEMAVRGGSQCGYCTPGFVCSMAAEFYRPERVATGPGPSGDAHERGPNGFDLAALSGNLCR
CTGYRPIRDAAYALGSPAPDDPLAARVHRAAPALEATRLEDGTGVFVRPRDLAEALALLGEHPEAVPVAGCTDWGVEVNL
RGARAPYVVAVDRLPELRRVSLPAPSGGAFEIGAALSLSEVELALAGRVPLLAAVFPLFASRLIRNGATIGGNLATASPI
GDLAPALLALEASVVLVSTDGDRELPIAELFTGYRRSQLRPGELIRAVRIPQPLAGTTAFHKIAKRRYDDISSVAVAFAL
DVVDETVVRAKVGLGGVAATPIRARATEAALEGRTWSAETARAAAAVLGGEGTPMDDHRASAAYRAAMLEQSLLRLWAQG
PSDEGEASA

Specific function: Iron-Sulfur Subunit Of The Xanthine Dehydrogenase Complex (By Similarity). [C]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=505, Percent_Identity=33.2673267326733, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI71773480, Length=510, Percent_Identity=29.8039215686275, Blast_Score=148, Evalue=1e-35,
Organism=Escherichia coli, GI1786480, Length=178, Percent_Identity=41.0112359550562, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789232, Length=158, Percent_Identity=39.873417721519, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789231, Length=270, Percent_Identity=28.8888888888889, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=167, Percent_Identity=40.7185628742515, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=173, Percent_Identity=38.150289017341, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=168, Percent_Identity=38.0952380952381, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17737937, Length=505, Percent_Identity=32.6732673267327, Blast_Score=208, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24647201, Length=466, Percent_Identity=27.6824034334764, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24647199, Length=466, Percent_Identity=28.9699570815451, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24647197, Length=466, Percent_Identity=27.2532188841202, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24647195, Length=338, Percent_Identity=30.7692307692308, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647193, Length=473, Percent_Identity=27.6955602536998, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2; PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.7 [H]

Molecular weight: Translated: 50605; Mature: 50474

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAPSIPGVTVNGRRLSLAGVSPHTTTLDLLRGVGLTGAKEGCAEGECGACSVLVARPD
CCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCC
GEGIRWTALNACLVPAAALDGQELVTAEGLGTPEDLHPVQHEMAVRGGSQCGYCTPGFVC
CCCEEEEEHHHHHHHHHHCCCCCEEEECCCCCCHHCCHHHHHHHHCCCCCCCCCCHHHHH
SMAAEFYRPERVATGPGPSGDAHERGPNGFDLAALSGNLCRCTGYRPIRDAAYALGSPAP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHCCCCCC
DDPLAARVHRAAPALEATRLEDGTGVFVRPRDLAEALALLGEHPEAVPVAGCTDWGVEVN
CCHHHHHHHHHCCCHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCEECCCCCCCEEEE
LRGARAPYVVAVDRLPELRRVSLPAPSGGAFEIGAALSLSEVELALAGRVPLLAAVFPLF
ECCCCCCEEEEECCCCCHHEECCCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHH
ASRLIRNGATIGGNLATASPIGDLAPALLALEASVVLVSTDGDRELPIAELFTGYRRSQL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCC
RPGELIRAVRIPQPLAGTTAFHKIAKRRYDDISSVAVAFALDVVDETVVRAKVGLGGVAA
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TPIRARATEAALEGRTWSAETARAAAAVLGGEGTPMDDHRASAAYRAAMLEQSLLRLWAQ
CCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GPSDEGEASA
CCCCCCCCCC
>Mature Secondary Structure 
AAAPSIPGVTVNGRRLSLAGVSPHTTTLDLLRGVGLTGAKEGCAEGECGACSVLVARPD
CCCCCCCCEEECCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCC
GEGIRWTALNACLVPAAALDGQELVTAEGLGTPEDLHPVQHEMAVRGGSQCGYCTPGFVC
CCCEEEEEHHHHHHHHHHCCCCCEEEECCCCCCHHCCHHHHHHHHCCCCCCCCCCHHHHH
SMAAEFYRPERVATGPGPSGDAHERGPNGFDLAALSGNLCRCTGYRPIRDAAYALGSPAP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHCCCCCC
DDPLAARVHRAAPALEATRLEDGTGVFVRPRDLAEALALLGEHPEAVPVAGCTDWGVEVN
CCHHHHHHHHHCCCHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCEECCCCCCCEEEE
LRGARAPYVVAVDRLPELRRVSLPAPSGGAFEIGAALSLSEVELALAGRVPLLAAVFPLF
ECCCCCCEEEEECCCCCHHEECCCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHH
ASRLIRNGATIGGNLATASPIGDLAPALLALEASVVLVSTDGDRELPIAELFTGYRRSQL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCC
RPGELIRAVRIPQPLAGTTAFHKIAKRRYDDISSVAVAFALDVVDETVVRAKVGLGGVAA
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TPIRARATEAALEGRTWSAETARAAAAVLGGEGTPMDDHRASAAYRAAMLEQSLLRLWAQ
CCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GPSDEGEASA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8143744; 7502041; 8799115; 11713686 [H]