The gene/protein map for NC_008699 is currently unavailable.
Definition Nocardioides sp. JS614 chromosome, complete genome.
Accession NC_008699
Length 4,985,871

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The map label for this gene is echA12 [H]

Identifier: 119715757

GI number: 119715757

Start: 1615060

End: 1615899

Strand: Direct

Name: echA12 [H]

Synonym: Noca_1521

Alternate gene names: 119715757

Gene position: 1615060-1615899 (Clockwise)

Preceding gene: 119715753

Following gene: 119715758

Centisome position: 32.39

GC content: 74.64

Gene sequence:

>840_bases
ATGCCTGAGCCCACGACCGCGTCCGCGACCGCCCCGACGCCCACCCCACCGGACCTCACCGACCTGCGCCTCGAGCGGCC
CTCCGACGGGGTCGCCGTGCTCACCCTCGACAACCCCGACCAGCGCAACGCGATGTCGGATGCGATGACCTCCTCATGGG
TCCGGGCGATCGACGCCCTGGCCGCCGACTCGTCGGTGCGGGTCGTGGTGGTCACCGGCGGGGGCTCGGCGTTCTGCTCC
GGCGGCAACACCTCGTGGATCGCGAGCGAGCCGGACGCGACCGTCGACGAGCTGCGCACCCGGATGGTCGCGTTCTACCG
GGCCTGGCTGTCGATCCGGCGCCTCGAGGTGCCGACGATCGCGGCCGTCAACGGCCCCGCGATCGGCGCGGGCCTGTGCC
TGGCCCTCGCCTGCGACGTGCGGTACGCCGCCGCCGGCGCGCGGCTCGGCGCTCCGTTCGTCAAGCTCGGCATGCACGCC
GGCATGGCCGGGACCTACCTGCTGCCGAACGTCGTGGGGGAGGCACACGCCCGCGACCTCCTGCTGACCGGGCGGGTCGT
CGACGCCGACGAGGCACTGCGCCTGGGCCTGGTCTCCCGGGTGATCGAGCCGGAGTCCTTCCGCGACGAGGTCCTGGCGA
CCGCCGCGGGGATCGCGGCCACCGCCCCGATCGCCAGCCGACTCACCAAGCTGGCGCTCGCCGACGGCGGCCACGCGGAC
TTCGAGAGCTGCCTGCAGTGGGAGGCGCTCGCCCAGCCCGTCACGCTGGCCACCGCGGACCTCCAGGAGGGCATCCGGGC
CGCGCAGGAGAAGCGGGCGGCGGTCTTCACCGGCCGTTGA

Upstream 100 bases:

>100_bases
ACAGACCCTACGGCACCAGCGGTGAGATGCGTGTCAGGCGCACCGTGAGCGGTGAATCGGGTCACGGCGCGTCGCGGCGG
CGATCAGTACGTTGGGCCCC

Downstream 100 bases:

>100_bases
CGTGAGCAGGGACGTGAGGAGGCCCCCGGCCGCATCTGGACACTTGCCTTCCCCTTGCGAGTGTCCGTCCGCGGCCGAGG
GCCTCATCTGCGCCCCACGC

Product: short chain enoyl-CoA hydratase / enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MPEPTTASATAPTPTPPDLTDLRLERPSDGVAVLTLDNPDQRNAMSDAMTSSWVRAIDALAADSSVRVVVVTGGGSAFCS
GGNTSWIASEPDATVDELRTRMVAFYRAWLSIRRLEVPTIAAVNGPAIGAGLCLALACDVRYAAAGARLGAPFVKLGMHA
GMAGTYLLPNVVGEAHARDLLLTGRVVDADEALRLGLVSRVIEPESFRDEVLATAAGIAATAPIASRLTKLALADGGHAD
FESCLQWEALAQPVTLATADLQEGIRAAQEKRAAVFTGR

Sequences:

>Translated_279_residues
MPEPTTASATAPTPTPPDLTDLRLERPSDGVAVLTLDNPDQRNAMSDAMTSSWVRAIDALAADSSVRVVVVTGGGSAFCS
GGNTSWIASEPDATVDELRTRMVAFYRAWLSIRRLEVPTIAAVNGPAIGAGLCLALACDVRYAAAGARLGAPFVKLGMHA
GMAGTYLLPNVVGEAHARDLLLTGRVVDADEALRLGLVSRVIEPESFRDEVLATAAGIAATAPIASRLTKLALADGGHAD
FESCLQWEALAQPVTLATADLQEGIRAAQEKRAAVFTGR
>Mature_278_residues
PEPTTASATAPTPTPPDLTDLRLERPSDGVAVLTLDNPDQRNAMSDAMTSSWVRAIDALAADSSVRVVVVTGGGSAFCSG
GNTSWIASEPDATVDELRTRMVAFYRAWLSIRRLEVPTIAAVNGPAIGAGLCLALACDVRYAAAGARLGAPFVKLGMHAG
MAGTYLLPNVVGEAHARDLLLTGRVVDADEALRLGLVSRVIEPESFRDEVLATAAGIAATAPIASRLTKLALADGGHADF
ESCLQWEALAQPVTLATADLQEGIRAAQEKRAAVFTGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=30.8300395256917, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4502327, Length=269, Percent_Identity=33.0855018587361, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI70995211, Length=263, Percent_Identity=31.9391634980989, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI45643119, Length=203, Percent_Identity=29.5566502463054, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI260275230, Length=203, Percent_Identity=29.5566502463054, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI260274832, Length=203, Percent_Identity=29.5566502463054, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI31542718, Length=254, Percent_Identity=29.5275590551181, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI68989263, Length=186, Percent_Identity=31.7204301075269, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI221136756, Length=207, Percent_Identity=29.4685990338164, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI221136753, Length=207, Percent_Identity=29.4685990338164, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI221307494, Length=201, Percent_Identity=29.8507462686567, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI4757966, Length=201, Percent_Identity=27.363184079602, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI51538581, Length=201, Percent_Identity=27.363184079602, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI25453481, Length=201, Percent_Identity=27.363184079602, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI51538573, Length=201, Percent_Identity=27.363184079602, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI116235487, Length=210, Percent_Identity=25.7142857142857, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI20127408, Length=178, Percent_Identity=30.8988764044944, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4757968, Length=204, Percent_Identity=26.4705882352941, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI49355787, Length=204, Percent_Identity=26.4705882352941, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI150378541, Length=258, Percent_Identity=27.1317829457364, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI261878539, Length=76, Percent_Identity=48.6842105263158, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI213417737, Length=181, Percent_Identity=25.414364640884, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI157694516, Length=181, Percent_Identity=25.414364640884, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787659, Length=251, Percent_Identity=35.4581673306773, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788597, Length=288, Percent_Identity=29.8611111111111, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=30.5343511450382, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790281, Length=186, Percent_Identity=32.258064516129, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=30.8300395256917, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788682, Length=183, Percent_Identity=35.5191256830601, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87082183, Length=260, Percent_Identity=25.3846153846154, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=262, Percent_Identity=29.7709923664122, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI25145438, Length=250, Percent_Identity=31.6, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=228, Percent_Identity=32.4561403508772, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17536985, Length=290, Percent_Identity=28.6206896551724, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=260, Percent_Identity=30.3846153846154, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17558304, Length=188, Percent_Identity=33.5106382978723, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144276, Length=195, Percent_Identity=34.8717948717949, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508951, Length=195, Percent_Identity=34.8717948717949, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508953, Length=195, Percent_Identity=34.8717948717949, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=243, Percent_Identity=30.8641975308642, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=241, Percent_Identity=24.896265560166, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=211, Percent_Identity=25.5924170616114, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=190, Percent_Identity=23.6842105263158, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129971, Length=277, Percent_Identity=29.9638989169675, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24653477, Length=277, Percent_Identity=29.9638989169675, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=32.0754716981132, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21357171, Length=202, Percent_Identity=32.1782178217822, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24654903, Length=172, Percent_Identity=30.2325581395349, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19920382, Length=226, Percent_Identity=32.3008849557522, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24650670, Length=244, Percent_Identity=27.0491803278689, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19921000, Length=182, Percent_Identity=32.4175824175824, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583077, Length=182, Percent_Identity=32.4175824175824, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583079, Length=182, Percent_Identity=32.4175824175824, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922422, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 29074; Mature: 28943

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MPEPTTASATAPTPTPPDLTDLRLERPSDGVAVLTLDNPDQRNAMSDAMTSSWVRAIDAL
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
AADSSVRVVVVTGGGSAFCSGGNTSWIASEPDATVDELRTRMVAFYRAWLSIRRLEVPTI
HCCCCEEEEEEECCCCEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
AAVNGPAIGAGLCLALACDVRYAAAGARLGAPFVKLGMHAGMAGTYLLPNVVGEAHARDL
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
LLTGRVVDADEALRLGLVSRVIEPESFRDEVLATAAGIAATAPIASRLTKLALADGGHAD
EEECCEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FESCLQWEALAQPVTLATADLQEGIRAAQEKRAAVFTGR
HHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHCCEECCCC
>Mature Secondary Structure 
PEPTTASATAPTPTPPDLTDLRLERPSDGVAVLTLDNPDQRNAMSDAMTSSWVRAIDAL
CCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
AADSSVRVVVVTGGGSAFCSGGNTSWIASEPDATVDELRTRMVAFYRAWLSIRRLEVPTI
HCCCCEEEEEEECCCCEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
AAVNGPAIGAGLCLALACDVRYAAAGARLGAPFVKLGMHAGMAGTYLLPNVVGEAHARDL
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
LLTGRVVDADEALRLGLVSRVIEPESFRDEVLATAAGIAATAPIASRLTKLALADGGHAD
EEECCEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FESCLQWEALAQPVTLATADLQEGIRAAQEKRAAVFTGR
HHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]