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The map label for this gene is polX [H]

Identifier: 119715758

GI number: 119715758

Start: 1616182

End: 1617318

Strand: Direct

Name: polX [H]

Synonym: Noca_1522

Alternate gene names: 119715758

Gene position: 1616182-1617318 (Clockwise)

Preceding gene: 119715757

Following gene: 119715759

Centisome position: 32.42

GC content: 72.91

Gene sequence:

>1137_bases
ATGGCTGTCCACCGGGTGTGGACGAAAGAAAACTGGGCCAACCAGCGGGAGAACCGACGCGAGAGAGAGGTCAGCGGCGT
GCCGGACCAGACAGCGGGCGACGAGTACGGCGCCGGGCCGGTCGCCGCCCTGCGCCGGATCGCGTTCCTGCTCGAGCGCG
GCCGGGAGGACACCTACAAGGTCAAGGCGTTCCGCGGTGCCGCTGCCGCGATCCTGCCGCTGACGGCCGAGCAGGTCGCC
GCGGCGGTCGAGGACGGCAGCCTGACGTCGCTGCCGGGTGTCGGTGCGAGCACGGCCCGGGTCATCGCCGATGCCGTGCG
CGGGGTGCTGCCGACCCGGCTGGCCGAGCTCGAGCGCGAGCACGGCGGTGACCTGGCGAGCGGCGGCCAGGGGCTCCGCG
CCGCCCTGCGCGGCGACCTGCACTCCCACTCCGACTGGTCCGACGGCGGCTCGCCGATCGAGGAGATGGCGTTCACGGCC
ATCGAGCTCGGCCACGACTACCTGGTGCTCACCGACCACTCGCCGCGGCTGACCGTCGCGCACGGCCTCAGCGCCGAGCG
GTTGACCCGCCAGCTGGGCGTGGTCGACGCGGTCAACCGGCACCTCTCCGGGGTCGACGACTCCTTCACGCTGCTCAAGG
GGATCGAGGTCGACATCCTCGACGACGGCTCGCTGGACCAGGACGACGACCTGCTGGCGCAGCTCGACGTCCGGGTCGCG
AGCGTGCACTCCAAGCTCAAGATGGAGCCGGCGGACATGACCCGGCGGATGATCGGCGCGATCCGCAACCCGCGCACCAA
CGTCCTCGGTCACTGCACCGGCCGGCTGGTGACCGGCAACCGCGGCACCCGCCCGGGCTCCCGTTTCGACGCGGGTGCGG
TGTTCGAGGCCTGCGCGGAGCACGACGTCGCGGTCGAGATCAACTCCCGGCCCGAGCGGCGGGACCCGCCGACGGCGCTG
CTGGAGCTGGCCCGGGACGCCGGCTGCGTGTTCTCCATCGACAGCGACGCCCACGCCCCCGGGCAGCTGGACTTCCTGGT
CTACGGCTGCGAGCGGGCCGAGGCGGCCGGCATCGACCCGGACCGGATCGTCAACACCTGGCCGCGGGAGCGGTTGCTGG
CCTGGGCGAGGAAGTAG

Upstream 100 bases:

>100_bases
CGTGCCGGTGGAGGAGGCCGGATCGATCCTGGAACAGGCTGTGGACAGCTCGGCTCGGGGACACCGGCGCTCCCGTCGTA
CTCGGCGCTGACCAGGGAGA

Downstream 100 bases:

>100_bases
CGTTCGGCCATGGGACGTCCCGAGGTGGAGGTGCGGCGCTCGAAGCGGCGTCGCCGTACCGTCTCGGCCTACCGCGACGG
TGACCGCGTCGTCGTGATGA

Product: hypothetical protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MAVHRVWTKENWANQRENRREREVSGVPDQTAGDEYGAGPVAALRRIAFLLERGREDTYKVKAFRGAAAAILPLTAEQVA
AAVEDGSLTSLPGVGASTARVIADAVRGVLPTRLAELEREHGGDLASGGQGLRAALRGDLHSHSDWSDGGSPIEEMAFTA
IELGHDYLVLTDHSPRLTVAHGLSAERLTRQLGVVDAVNRHLSGVDDSFTLLKGIEVDILDDGSLDQDDDLLAQLDVRVA
SVHSKLKMEPADMTRRMIGAIRNPRTNVLGHCTGRLVTGNRGTRPGSRFDAGAVFEACAEHDVAVEINSRPERRDPPTAL
LELARDAGCVFSIDSDAHAPGQLDFLVYGCERAEAAGIDPDRIVNTWPRERLLAWARK

Sequences:

>Translated_378_residues
MAVHRVWTKENWANQRENRREREVSGVPDQTAGDEYGAGPVAALRRIAFLLERGREDTYKVKAFRGAAAAILPLTAEQVA
AAVEDGSLTSLPGVGASTARVIADAVRGVLPTRLAELEREHGGDLASGGQGLRAALRGDLHSHSDWSDGGSPIEEMAFTA
IELGHDYLVLTDHSPRLTVAHGLSAERLTRQLGVVDAVNRHLSGVDDSFTLLKGIEVDILDDGSLDQDDDLLAQLDVRVA
SVHSKLKMEPADMTRRMIGAIRNPRTNVLGHCTGRLVTGNRGTRPGSRFDAGAVFEACAEHDVAVEINSRPERRDPPTAL
LELARDAGCVFSIDSDAHAPGQLDFLVYGCERAEAAGIDPDRIVNTWPRERLLAWARK
>Mature_377_residues
AVHRVWTKENWANQRENRREREVSGVPDQTAGDEYGAGPVAALRRIAFLLERGREDTYKVKAFRGAAAAILPLTAEQVAA
AVEDGSLTSLPGVGASTARVIADAVRGVLPTRLAELEREHGGDLASGGQGLRAALRGDLHSHSDWSDGGSPIEEMAFTAI
ELGHDYLVLTDHSPRLTVAHGLSAERLTRQLGVVDAVNRHLSGVDDSFTLLKGIEVDILDDGSLDQDDDLLAQLDVRVAS
VHSKLKMEPADMTRRMIGAIRNPRTNVLGHCTGRLVTGNRGTRPGSRFDAGAVFEACAEHDVAVEINSRPERRDPPTALL
ELARDAGCVFSIDSDAHAPGQLDFLVYGCERAEAAGIDPDRIVNTWPRERLLAWARK

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40901; Mature: 40770

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHRVWTKENWANQRENRREREVSGVPDQTAGDEYGAGPVAALRRIAFLLERGREDTYK
CCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
VKAFRGAAAAILPLTAEQVAAAVEDGSLTSLPGVGASTARVIADAVRGVLPTRLAELERE
EEECCCCCHHEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HGGDLASGGQGLRAALRGDLHSHSDWSDGGSPIEEMAFTAIELGHDYLVLTDHSPRLTVA
HCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEE
HGLSAERLTRQLGVVDAVNRHLSGVDDSFTLLKGIEVDILDDGSLDQDDDLLAQLDVRVA
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHH
SVHSKLKMEPADMTRRMIGAIRNPRTNVLGHCTGRLVTGNRGTRPGSRFDAGAVFEACAE
HHHHHHCCCHHHHHHHHHHHHCCCCCCHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHCC
HDVAVEINSRPERRDPPTALLELARDAGCVFSIDSDAHAPGQLDFLVYGCERAEAAGIDP
CCEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCH
DRIVNTWPRERLLAWARK
HHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
AVHRVWTKENWANQRENRREREVSGVPDQTAGDEYGAGPVAALRRIAFLLERGREDTYK
CCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
VKAFRGAAAAILPLTAEQVAAAVEDGSLTSLPGVGASTARVIADAVRGVLPTRLAELERE
EEECCCCCHHEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HGGDLASGGQGLRAALRGDLHSHSDWSDGGSPIEEMAFTAIELGHDYLVLTDHSPRLTVA
HCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEE
HGLSAERLTRQLGVVDAVNRHLSGVDDSFTLLKGIEVDILDDGSLDQDDDLLAQLDVRVA
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHH
SVHSKLKMEPADMTRRMIGAIRNPRTNVLGHCTGRLVTGNRGTRPGSRFDAGAVFEACAE
HHHHHHCCCHHHHHHHHHHHHCCCCCCHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHCC
HDVAVEINSRPERRDPPTALLELARDAGCVFSIDSDAHAPGQLDFLVYGCERAEAAGIDP
CCEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCH
DRIVNTWPRERLLAWARK
HHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]