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The map label for this gene is deoD [H]

Identifier: 119715749

GI number: 119715749

Start: 1607944

End: 1608675

Strand: Reverse

Name: deoD [H]

Synonym: Noca_1513

Alternate gene names: 119715749

Gene position: 1608675-1607944 (Counterclockwise)

Preceding gene: 119715751

Following gene: 119715748

Centisome position: 32.26

GC content: 71.45

Gene sequence:

>732_bases
GTGAGCACCCACATCGGCGCCCGGCCGGGCGACATCGCCCCCCTCGTCCTCATGCCCGGAGACCCGCTGCGCGCCCGGTG
GATCGCAGACACGTTCCTGGACGACGCGCGCTGCTACACCGAGGTGCGCGGCATGTACGGCTACACCGGCAGCTGGCAGG
GTCAGCGCGTCTCGGTGCAGGGCTCCGGGATGGGCCAGCCGTCGCTGGCGATCTACGCCAACGAGCTGTTCCGGGAGTAC
GACGTGCAGTCGATCATCCGGGTCGGCTCGTGCGGCGCGCTGAGCGAGCGGCTCGCCGTACGCGACATCGTGATCGCCTC
GGGCGCCTGCACCGACTCCTCGATGAACCGGATCCGGTTCGAGGGGCTGGACTACGCGCCGGTCGCCGACTTCGGCCTGC
TCCGCGCCGCCCACGACGCGGCCACGGCGAAGCAGCTCGCCGAGGGGGTGCACGTCGGGCTGATCTTCAGCAGCGACTCG
TTCTACCCCGCCAGGCCCGAGCTGGCCGCACGCATGGTCGACTTCGGCGTACTGGCGGTCGAGATGGAGGCGAGCGCGCT
CTACACGCTGGCCGCCAAGCACGGCCGGCGGGCACTCACGATCTGCACGGTCAGCGACCACGTCGTCACCGGCGAGGAGA
CGTCCGCGCAGGAGCGCGAGCAGACGTTCGGGACGATGGTGGAGATCGCGCTCGCCGCCGGGCTCGCCCAGGCCGTGGCG
CCCCAGGACTAA

Upstream 100 bases:

>100_bases
GTCGTCGCCGCGGTGCAGCGCGGTGCGGTCGTGGGGGTTGGCCGCGAGCTGCTGGTGCGGATACGTCACCCGGGCGAGGT
TAGCCCTAGCCTTGCCCTAC

Downstream 100 bases:

>100_bases
CCAGCCGGGTCGGTGCGTTCAGAGGACATGGAGATCCTCGACGCGGTGGTGATCGGTGCGGGCCAGGCCGGCCTGTCCGC
GTCGTACCACCTCACCCGCC

Product: purine-nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSTHIGARPGDIAPLVLMPGDPLRARWIADTFLDDARCYTEVRGMYGYTGSWQGQRVSVQGSGMGQPSLAIYANELFREY
DVQSIIRVGSCGALSERLAVRDIVIASGACTDSSMNRIRFEGLDYAPVADFGLLRAAHDAATAKQLAEGVHVGLIFSSDS
FYPARPELAARMVDFGVLAVEMEASALYTLAAKHGRRALTICTVSDHVVTGEETSAQEREQTFGTMVEIALAAGLAQAVA
PQD

Sequences:

>Translated_243_residues
MSTHIGARPGDIAPLVLMPGDPLRARWIADTFLDDARCYTEVRGMYGYTGSWQGQRVSVQGSGMGQPSLAIYANELFREY
DVQSIIRVGSCGALSERLAVRDIVIASGACTDSSMNRIRFEGLDYAPVADFGLLRAAHDAATAKQLAEGVHVGLIFSSDS
FYPARPELAARMVDFGVLAVEMEASALYTLAAKHGRRALTICTVSDHVVTGEETSAQEREQTFGTMVEIALAAGLAQAVA
PQD
>Mature_242_residues
STHIGARPGDIAPLVLMPGDPLRARWIADTFLDDARCYTEVRGMYGYTGSWQGQRVSVQGSGMGQPSLAIYANELFREYD
VQSIIRVGSCGALSERLAVRDIVIASGACTDSSMNRIRFEGLDYAPVADFGLLRAAHDAATAKQLAEGVHVGLIFSSDSF
YPARPELAARMVDFGVLAVEMEASALYTLAAKHGRRALTICTVSDHVVTGEETSAQEREQTFGTMVEIALAAGLAQAVAP
QD

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=52.991452991453, Blast_Score=253, Evalue=7e-69,
Organism=Escherichia coli, GI1790265, Length=246, Percent_Identity=28.4552845528455, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 26049; Mature: 25918

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHIGARPGDIAPLVLMPGDPLRARWIADTFLDDARCYTEVRGMYGYTGSWQGQRVSVQ
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
GSGMGQPSLAIYANELFREYDVQSIIRVGSCGALSERLAVRDIVIASGACTDSSMNRIRF
CCCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHEEEECCCCCCCCCCEEEE
EGLDYAPVADFGLLRAAHDAATAKQLAEGVHVGLIFSSDSFYPARPELAARMVDFGVLAV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHCEEEE
EMEASALYTLAAKHGRRALTICTVSDHVVTGEETSAQEREQTFGTMVEIALAAGLAQAVA
EECHHHHHHHHHHCCCEEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PQD
CCC
>Mature Secondary Structure 
STHIGARPGDIAPLVLMPGDPLRARWIADTFLDDARCYTEVRGMYGYTGSWQGQRVSVQ
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
GSGMGQPSLAIYANELFREYDVQSIIRVGSCGALSERLAVRDIVIASGACTDSSMNRIRF
CCCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHEEEECCCCCCCCCCEEEE
EGLDYAPVADFGLLRAAHDAATAKQLAEGVHVGLIFSSDSFYPARPELAARMVDFGVLAV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHCEEEE
EMEASALYTLAAKHGRRALTICTVSDHVVTGEETSAQEREQTFGTMVEIALAAGLAQAVA
EECHHHHHHHHHHCCCEEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PQD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]