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The map label for this gene is add1 [H]

Identifier: 119715591

GI number: 119715591

Start: 1432838

End: 1433884

Strand: Direct

Name: add1 [H]

Synonym: Noca_1355

Alternate gene names: 119715591

Gene position: 1432838-1433884 (Clockwise)

Preceding gene: 119715590

Following gene: 119715592

Centisome position: 28.74

GC content: 72.78

Gene sequence:

>1047_bases
GTGAGTACCCGGGACCCCCTCGCCACCTTCATCGCCGGACTGCCCAAGGCCGAGCTGCACGTCCACCATGTCGGGTCCGC
GTCGCCTCGGATCGTCTCCGAGCTCGCCGAGCGGCATCCGGGGACTGTCCCGAGCGACCCGGACGCCCTGCGTCGGTTCT
TCGAGTTCCGCGACTTCGCGCACTTCGTCGAGGTCTACCTCGCGGTGGTCGACCTGATCCGTACGCCCGAGGACATCCGC
TACCTGACCCACGAGATCGGGCGGGAGATGGCCACGGGCCAGGGCCTGCGGTACGCCGAGCTCACGTGCACGCCGTACAC
CTCAGTGCGACCGCACGAGGAGGGCAAGGGCATGCCGATCGAGGCCTACACCGAGGCGATCGAGGACGCCCGGGTCGCGG
TCGAGCGTGACTTCGGTCTGGTGCTGCGCTGGATCTACGACATCCCCGGCGAGTTCGGCCTGCCCGCCGCCGACGCCACG
CTCGGGTACGCCCTCGGCCACCGCCCGGAGGCCCTGGTCGGCTTCGGGCTCGGCGGCCCCGAGATCGGGGTGCCGCGACC
CCAGTTCCGACCGCACTTCGACGCGGCTCGCGCGGCCGGCCTGCACAGCGTCCCGCACGCGGGGGAGACGACCGGCCCCG
AGACGGTCCGGCACGCGATCGAGCTGCTGGGCGCGGAGCGGATCGGGCACGGCACGTCGTCCGCCCAGGACGCCGGGCTC
CTGGCGCTGCTCGCCGAGCGCGGTATCCCGCTCGAGGTGTGCCCCTCCTCGAACGTCGCGACCCGGGCGGTGGCCGACCT
GGCGGAGCACCCGATCCGGGCGTTCCGCGACGCGGGCGTGGTCGTGACGGTCAACTCCGACGACCCGCCGATGTTCAACA
CCACGCTGAACCGCGAGTACGAGGTGGCGGCCGGGCTGCTCGGCCTCGACCGGGCCGGAGTGGCCGAGCTGGCGCGCACC
GCCGTACGTGCGTCGTTCGCCGAGCTCGACGTCCAGGCCCGGATCCTGGGAGAGATCGACGCCTACGTCGCGTCCGGTCC
GGCCTGA

Upstream 100 bases:

>100_bases
GGGAACGGTGCGTAGTCCCGGCGACCGGAGGGGGCGACCCCGGGCCCACCGACGCGGCGTGGATTCCGCTTCGGCGCCCG
GCGCTGACAGACTCCGTCGG

Downstream 100 bases:

>100_bases
CGCCGGCTTCTCCGGGCCGGAAGAAGGAATGGGCCCCGCGAGCTCATACCAAGCGGGGCCGACACCTTTGTATCCCGAAC
GGGGCCGGATTCCTGGGATT

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase 1 [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSTRDPLATFIAGLPKAELHVHHVGSASPRIVSELAERHPGTVPSDPDALRRFFEFRDFAHFVEVYLAVVDLIRTPEDIR
YLTHEIGREMATGQGLRYAELTCTPYTSVRPHEEGKGMPIEAYTEAIEDARVAVERDFGLVLRWIYDIPGEFGLPAADAT
LGYALGHRPEALVGFGLGGPEIGVPRPQFRPHFDAARAAGLHSVPHAGETTGPETVRHAIELLGAERIGHGTSSAQDAGL
LALLAERGIPLEVCPSSNVATRAVADLAEHPIRAFRDAGVVVTVNSDDPPMFNTTLNREYEVAAGLLGLDRAGVAELART
AVRASFAELDVQARILGEIDAYVASGPA

Sequences:

>Translated_348_residues
MSTRDPLATFIAGLPKAELHVHHVGSASPRIVSELAERHPGTVPSDPDALRRFFEFRDFAHFVEVYLAVVDLIRTPEDIR
YLTHEIGREMATGQGLRYAELTCTPYTSVRPHEEGKGMPIEAYTEAIEDARVAVERDFGLVLRWIYDIPGEFGLPAADAT
LGYALGHRPEALVGFGLGGPEIGVPRPQFRPHFDAARAAGLHSVPHAGETTGPETVRHAIELLGAERIGHGTSSAQDAGL
LALLAERGIPLEVCPSSNVATRAVADLAEHPIRAFRDAGVVVTVNSDDPPMFNTTLNREYEVAAGLLGLDRAGVAELART
AVRASFAELDVQARILGEIDAYVASGPA
>Mature_347_residues
STRDPLATFIAGLPKAELHVHHVGSASPRIVSELAERHPGTVPSDPDALRRFFEFRDFAHFVEVYLAVVDLIRTPEDIRY
LTHEIGREMATGQGLRYAELTCTPYTSVRPHEEGKGMPIEAYTEAIEDARVAVERDFGLVLRWIYDIPGEFGLPAADATL
GYALGHRPEALVGFGLGGPEIGVPRPQFRPHFDAARAAGLHSVPHAGETTGPETVRHAIELLGAERIGHGTSSAQDAGLL
ALLAERGIPLEVCPSSNVATRAVADLAEHPIRAFRDAGVVVTVNSDDPPMFNTTLNREYEVAAGLLGLDRAGVAELARTA
VRASFAELDVQARILGEIDAYVASGPA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=344, Percent_Identity=25, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI29029552, Length=128, Percent_Identity=33.59375, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI29029550, Length=128, Percent_Identity=33.59375, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI61175224, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787910, Length=318, Percent_Identity=31.7610062893082, Blast_Score=151, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI32565969, Length=158, Percent_Identity=32.9113924050633, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538512, Length=214, Percent_Identity=29.4392523364486, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324188, Length=349, Percent_Identity=26.3610315186246, Blast_Score=105, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24645260, Length=343, Percent_Identity=27.9883381924198, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37427; Mature: 37295

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRDPLATFIAGLPKAELHVHHVGSASPRIVSELAERHPGTVPSDPDALRRFFEFRDFA
CCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
HFVEVYLAVVDLIRTPEDIRYLTHEIGREMATGQGLRYAELTCTPYTSVRPHEEGKGMPI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCH
EAYTEAIEDARVAVERDFGLVLRWIYDIPGEFGLPAADATLGYALGHRPEALVGFGLGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCC
EIGVPRPQFRPHFDAARAAGLHSVPHAGETTGPETVRHAIELLGAERIGHGTSSAQDAGL
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LALLAERGIPLEVCPSSNVATRAVADLAEHPIRAFRDAGVVVTVNSDDPPMFNTTLNREY
HHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCH
EVAAGLLGLDRAGVAELARTAVRASFAELDVQARILGEIDAYVASGPA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
STRDPLATFIAGLPKAELHVHHVGSASPRIVSELAERHPGTVPSDPDALRRFFEFRDFA
CCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
HFVEVYLAVVDLIRTPEDIRYLTHEIGREMATGQGLRYAELTCTPYTSVRPHEEGKGMPI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCH
EAYTEAIEDARVAVERDFGLVLRWIYDIPGEFGLPAADATLGYALGHRPEALVGFGLGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCC
EIGVPRPQFRPHFDAARAAGLHSVPHAGETTGPETVRHAIELLGAERIGHGTSSAQDAGL
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LALLAERGIPLEVCPSSNVATRAVADLAEHPIRAFRDAGVVVTVNSDDPPMFNTTLNREY
HHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCCH
EVAAGLLGLDRAGVAELARTAVRASFAELDVQARILGEIDAYVASGPA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]