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The map label for this gene is degU [H]

Identifier: 119715499

GI number: 119715499

Start: 1337547

End: 1338395

Strand: Direct

Name: degU [H]

Synonym: Noca_1263

Alternate gene names: 119715499

Gene position: 1337547-1338395 (Clockwise)

Preceding gene: 119715498

Following gene: 119715500

Centisome position: 26.83

GC content: 73.03

Gene sequence:

>849_bases
ATGCGCTCGGCTGACCGGGGGGCGAGGCGCCGGCCGACGCGCGGACGCGGACGGCCCCGGGTGCGTGCCACGGAGGAGTT
GAGCGCCTACGCTTCCATCGTGCCCATCCGCGTCCTCCTGGTGGACGACGTCGTTGAGGTACGCCGGCTGGTCCGCACCT
CGCTTCGCTTCCGGGGTGGTTTCGAGGTCGTGGGCGAGGCGGCGGACGGTGTCGGGGCCGTCCGGCTCGCCGCACAGTTG
CGTCCCGACGTCGTCGTACTCGACCTCGGCCTGCCCGACATCGCGGGCCGCGAGGTCCTCACCCGGGTGCGCGAGGTCTC
GCCCGTGACCAAGGTCGTCGTCTTCTCCGGGCTGGAGACCGCCGACCGCAGCTGGATCAACGACCACGCCGAGGGGTACG
TCGTCAAGGACGCCGACCTCGGCTACCTCGTCGACCTGCTCGAGTCGGTGGGCAACAGCGCCGACACCCGGGCCACGATC
GACCTCCCCGACGACCTGCGCAGCGTCAGCACCGCGCGCCGCTTCGTGCGCGAGAAGCTGGCCGAGTGGGGAGTCGACGG
GCCCGTCGATGACGCGCTGCTGGTGACCAGCGAGCTGGCCGCCAACGCCCTCACCCACGCCGGCTCCTCATACCGGCTCC
GGCTCTCGGTCAGCGAGCGAGCGCTGCGGATCGAGGTCGCCGACGGCGGGCCCGGCACCCCGGAGCCACAGCCGCTCACC
GAGACCGAGGAGCACGGCCGTGGCCTGCACCTGGTCGGGGCGCTCGCAGCGTCGTGGGGGATGGAGTCGGCCGGCAGCGG
GAAGCGGGTCTGGGCCGAGCTTCCGCTGTCGATCGCGGTCGCCGAGTAG

Upstream 100 bases:

>100_bases
CAGCTGGCCCGCTCCCACGACGGGGAGGCGACGTACCGTCCCGGTGGCGCCGACGGCACCGGCGGCTCGTTCGTGCTCAC
CCTGCCGCGCTCGGGTGCCG

Downstream 100 bases:

>100_bases
GCGGCCGAGTAGGCCGGGGCCGCGGCGCACCGTAACCTTGGTCCTTGTGGCAGGACCGGACTACGACACCGAGATCAAGC
AGCTCCAGGCGACGATGCAC

Product: response regulator receiver

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MRSADRGARRRPTRGRGRPRVRATEELSAYASIVPIRVLLVDDVVEVRRLVRTSLRFRGGFEVVGEAADGVGAVRLAAQL
RPDVVVLDLGLPDIAGREVLTRVREVSPVTKVVVFSGLETADRSWINDHAEGYVVKDADLGYLVDLLESVGNSADTRATI
DLPDDLRSVSTARRFVREKLAEWGVDGPVDDALLVTSELAANALTHAGSSYRLRLSVSERALRIEVADGGPGTPEPQPLT
ETEEHGRGLHLVGALAASWGMESAGSGKRVWAELPLSIAVAE

Sequences:

>Translated_282_residues
MRSADRGARRRPTRGRGRPRVRATEELSAYASIVPIRVLLVDDVVEVRRLVRTSLRFRGGFEVVGEAADGVGAVRLAAQL
RPDVVVLDLGLPDIAGREVLTRVREVSPVTKVVVFSGLETADRSWINDHAEGYVVKDADLGYLVDLLESVGNSADTRATI
DLPDDLRSVSTARRFVREKLAEWGVDGPVDDALLVTSELAANALTHAGSSYRLRLSVSERALRIEVADGGPGTPEPQPLT
ETEEHGRGLHLVGALAASWGMESAGSGKRVWAELPLSIAVAE
>Mature_282_residues
MRSADRGARRRPTRGRGRPRVRATEELSAYASIVPIRVLLVDDVVEVRRLVRTSLRFRGGFEVVGEAADGVGAVRLAAQL
RPDVVVLDLGLPDIAGREVLTRVREVSPVTKVVVFSGLETADRSWINDHAEGYVVKDADLGYLVDLLESVGNSADTRATI
DLPDDLRSVSTARRFVREKLAEWGVDGPVDDALLVTSELAANALTHAGSSYRLRLSVSERALRIEVADGGPGTPEPQPLT
ETEEHGRGLHLVGALAASWGMESAGSGKRVWAELPLSIAVAE

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=107, Percent_Identity=34.5794392523364, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 30383; Mature: 30383

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSADRGARRRPTRGRGRPRVRATEELSAYASIVPIRVLLVDDVVEVRRLVRTSLRFRGG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FEVVGEAADGVGAVRLAAQLRPDVVVLDLGLPDIAGREVLTRVREVSPVTKVVVFSGLET
HHEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCH
ADRSWINDHAEGYVVKDADLGYLVDLLESVGNSADTRATIDLPDDLRSVSTARRFVREKL
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AEWGVDGPVDDALLVTSELAANALTHAGSSYRLRLSVSERALRIEVADGGPGTPEPQPLT
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCCC
ETEEHGRGLHLVGALAASWGMESAGSGKRVWAELPLSIAVAE
CHHHHCCCEEHHHHHHHHCCCCCCCCCCEEEEECCEEEEECC
>Mature Secondary Structure
MRSADRGARRRPTRGRGRPRVRATEELSAYASIVPIRVLLVDDVVEVRRLVRTSLRFRGG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FEVVGEAADGVGAVRLAAQLRPDVVVLDLGLPDIAGREVLTRVREVSPVTKVVVFSGLET
HHEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCH
ADRSWINDHAEGYVVKDADLGYLVDLLESVGNSADTRATIDLPDDLRSVSTARRFVREKL
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AEWGVDGPVDDALLVTSELAANALTHAGSSYRLRLSVSERALRIEVADGGPGTPEPQPLT
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCCC
ETEEHGRGLHLVGALAASWGMESAGSGKRVWAELPLSIAVAE
CHHHHCCCEEHHHHHHHHCCCCCCCCCCEEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]