| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is braF [H]
Identifier: 119715417
GI number: 119715417
Start: 1254437
End: 1255249
Strand: Direct
Name: braF [H]
Synonym: Noca_1181
Alternate gene names: 119715417
Gene position: 1254437-1255249 (Clockwise)
Preceding gene: 119715416
Following gene: 119715418
Centisome position: 25.16
GC content: 66.42
Gene sequence:
>813_bases GTGCCTGAATCCAGCACGACCTTCCGCACCGAGCTGCCGACCCGGACCGCCCCGCGCCCGCGGCTCACCCTCACCGACGT CTCGAAGAGCTTCGCCGGCCGCACGGTGGTCGATGTCGAGGACCTCAGCCTCGGCGACCATCCCATCGAAGGACTCATCG GCCCGAACGGTGCGGGCAAGACGACCCTGATGCGCCTGATCATGGGGTCTCTCAGGGCTGACACCGGGCAGATCCGTCTC GAGCGGACGGGGCATCACGACGTCGTGCTCTCGCAGCTGCGCGCACACAAGATCGCTCAGTGCGGAGTCGTGAAGACCAA CCAGGTGATCACTGACTTCGAGGGGCTGACGATCCTCGACTCGCTTCTGCTCTCGGTCACTCCCGAACGTCGTGAGTTCC CCCTTCACCTGAAGGGGGAACGATCGACCTACGACGAGCACCGGGCCGAGATCGAGCGCCAGCTCGATCACTTCGGGCTG GGGAACACCCGCCGGCTGGCGCTCTCGGCGGGCGAGAAGAAGCTCGTCGACATCATCCGATGCCTGCTGCTGAAGCCTGC CGTCCTGCTCCTGGACGAGCCGACGGCGGGGCTTCCGGCAGAGGTGACCCAGAGGGTCATGGACGCCGTGGGCGGCCTGG CCGCCGACGGCACCACCGTCGTCATCATCGAGCACGACCTCGACGTGATCTGGAACCTCTGTACCCAGGTGACCTTCATG GCCGAAGGCCGGGTGATGCTCCGCGGTGAGCCGTCGGAGATCCGGGAACACGGGACCGTCGTCGAGAGCTACCTGGGCCA GGGTCATGTCTGA
Upstream 100 bases:
>100_bases GAGGTCCTGTTCGGACTGGCGCTCATCCTTGTCCTGATCTTCCGGCCGCTCGGCCTGCTCGGCCACATGCGGCGCGACCG ACTCATGAGGAGGATCCACG
Downstream 100 bases:
>100_bases GGCCACCAGGGTGCTCGAGGTCAGCGGCCTGCGAGCCGGCTACGACGGGATCGCCGTCCTCGACGAGGTCGACTTCACGG TCGGCGACGAGGTCTTCGCG
Product: ABC transporter-like protein
Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 270; Mature: 269
Protein sequence:
>270_residues MPESSTTFRTELPTRTAPRPRLTLTDVSKSFAGRTVVDVEDLSLGDHPIEGLIGPNGAGKTTLMRLIMGSLRADTGQIRL ERTGHHDVVLSQLRAHKIAQCGVVKTNQVITDFEGLTILDSLLLSVTPERREFPLHLKGERSTYDEHRAEIERQLDHFGL GNTRRLALSAGEKKLVDIIRCLLLKPAVLLLDEPTAGLPAEVTQRVMDAVGGLAADGTTVVIIEHDLDVIWNLCTQVTFM AEGRVMLRGEPSEIREHGTVVESYLGQGHV
Sequences:
>Translated_270_residues MPESSTTFRTELPTRTAPRPRLTLTDVSKSFAGRTVVDVEDLSLGDHPIEGLIGPNGAGKTTLMRLIMGSLRADTGQIRL ERTGHHDVVLSQLRAHKIAQCGVVKTNQVITDFEGLTILDSLLLSVTPERREFPLHLKGERSTYDEHRAEIERQLDHFGL GNTRRLALSAGEKKLVDIIRCLLLKPAVLLLDEPTAGLPAEVTQRVMDAVGGLAADGTTVVIIEHDLDVIWNLCTQVTFM AEGRVMLRGEPSEIREHGTVVESYLGQGHV >Mature_269_residues PESSTTFRTELPTRTAPRPRLTLTDVSKSFAGRTVVDVEDLSLGDHPIEGLIGPNGAGKTTLMRLIMGSLRADTGQIRLE RTGHHDVVLSQLRAHKIAQCGVVKTNQVITDFEGLTILDSLLLSVTPERREFPLHLKGERSTYDEHRAEIERQLDHFGLG NTRRLALSAGEKKLVDIIRCLLLKPAVLLLDEPTAGLPAEVTQRVMDAVGGLAADGTTVVIIEHDLDVIWNLCTQVTFMA EGRVMLRGEPSEIREHGTVVESYLGQGHV
Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]
COG id: COG0411
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI46592964, Length=210, Percent_Identity=27.6190476190476, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592956, Length=210, Percent_Identity=27.6190476190476, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592978, Length=210, Percent_Identity=27.6190476190476, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592971, Length=210, Percent_Identity=27.6190476190476, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592915, Length=210, Percent_Identity=27.6190476190476, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592898, Length=210, Percent_Identity=27.6190476190476, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI9955963, Length=246, Percent_Identity=28.8617886178862, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI215820660, Length=201, Percent_Identity=24.8756218905473, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI20143975, Length=201, Percent_Identity=24.8756218905473, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI27881501, Length=251, Percent_Identity=26.2948207171315, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI30795238, Length=251, Percent_Identity=26.2948207171315, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1789864, Length=261, Percent_Identity=28.735632183908, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1787792, Length=235, Percent_Identity=29.7872340425532, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI1789593, Length=246, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1788897, Length=237, Percent_Identity=29.1139240506329, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1788225, Length=245, Percent_Identity=28.9795918367347, Blast_Score=88, Evalue=8e-19, Organism=Escherichia coli, GI1788472, Length=228, Percent_Identity=24.5614035087719, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1790739, Length=237, Percent_Identity=29.535864978903, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787029, Length=242, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787370, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1788761, Length=259, Percent_Identity=30.1158301158301, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI48995001, Length=220, Percent_Identity=29.5454545454545, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1790525, Length=245, Percent_Identity=25.3061224489796, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87082268, Length=246, Percent_Identity=26.4227642276423, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789672, Length=238, Percent_Identity=27.3109243697479, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI87081709, Length=251, Percent_Identity=26.6932270916335, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787089, Length=226, Percent_Identity=28.7610619469027, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI87081782, Length=245, Percent_Identity=28.9795918367347, Blast_Score=73, Evalue=3e-14, Organism=Escherichia coli, GI1786872, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1790544, Length=243, Percent_Identity=27.1604938271605, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1790190, Length=249, Percent_Identity=24.0963855421687, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1786319, Length=207, Percent_Identity=27.536231884058, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1786398, Length=248, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1788210, Length=253, Percent_Identity=23.3201581027668, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI48994997, Length=243, Percent_Identity=28.3950617283951, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI1788644, Length=87, Percent_Identity=34.4827586206897, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1789873, Length=228, Percent_Identity=26.7543859649123, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI1790467, Length=245, Percent_Identity=28.1632653061224, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1786345, Length=238, Percent_Identity=26.890756302521, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI115533608, Length=250, Percent_Identity=24.8, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI25146777, Length=251, Percent_Identity=25.4980079681275, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI212646699, Length=243, Percent_Identity=24.2798353909465, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI193211015, Length=221, Percent_Identity=24.8868778280543, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI193211017, Length=221, Percent_Identity=24.8868778280543, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323217, Length=259, Percent_Identity=27.7992277992278, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324498, Length=247, Percent_Identity=26.7206477732794, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI24581191, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24581189, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24581193, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24581195, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI221512771, Length=236, Percent_Identity=22.0338983050847, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI28573573, Length=238, Percent_Identity=24.7899159663866, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI28573571, Length=238, Percent_Identity=24.7899159663866, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI116007184, Length=232, Percent_Identity=23.2758620689655, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI221500365, Length=232, Percent_Identity=23.2758620689655, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI24659289, Length=208, Percent_Identity=28.3653846153846, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 29648; Mature: 29516
Theoretical pI: Translated: 6.18; Mature: 6.18
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPESSTTFRTELPTRTAPRPRLTLTDVSKSFAGRTVVDVEDLSLGDHPIEGLIGPNGAGK CCCCCCEEEECCCCCCCCCCCEEHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCCCCCCH TTLMRLIMGSLRADTGQIRLERTGHHDVVLSQLRAHKIAQCGVVKTNQVITDFEGLTILD HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEECCCCHHCCCHHHHHH SLLLSVTPERREFPLHLKGERSTYDEHRAEIERQLDHFGLGNTRRLALSAGEKKLVDIIR HHHHHCCCCHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH CLLLKPAVLLLDEPTAGLPAEVTQRVMDAVGGLAADGTTVVIIEHDLDVIWNLCTQVTFM HHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHEEE AEGRVMLRGEPSEIREHGTVVESYLGQGHV ECCEEEEECCHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure PESSTTFRTELPTRTAPRPRLTLTDVSKSFAGRTVVDVEDLSLGDHPIEGLIGPNGAGK CCCCCEEEECCCCCCCCCCCEEHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCCCCCCH TTLMRLIMGSLRADTGQIRLERTGHHDVVLSQLRAHKIAQCGVVKTNQVITDFEGLTILD HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEECCCCHHCCCHHHHHH SLLLSVTPERREFPLHLKGERSTYDEHRAEIERQLDHFGLGNTRRLALSAGEKKLVDIIR HHHHHCCCCHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH CLLLKPAVLLLDEPTAGLPAEVTQRVMDAVGGLAADGTTVVIIEHDLDVIWNLCTQVTFM HHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHEEE AEGRVMLRGEPSEIREHGTVVESYLGQGHV ECCEEEEECCHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]
Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 2120183; 10984043 [H]