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The map label for this gene is xseA

Identifier: 119715314

GI number: 119715314

Start: 1133007

End: 1134242

Strand: Reverse

Name: xseA

Synonym: Noca_1074

Alternate gene names: 119715314

Gene position: 1134242-1133007 (Counterclockwise)

Preceding gene: 119715317

Following gene: 119715313

Centisome position: 22.75

GC content: 75.16

Gene sequence:

>1236_bases
ATGGCCCTGGAGAGCTCGCTCGAGTCGCCGGCCCCGGTCCGGCAGATCGCGAACGCGATCGCCGGCTGGGTCGACCGGCT
CGGCGCGGTGTGGGTCGAGGGCCAGGTGGCGCAGGTCAGCCGGCGACCCGGCCTGAACACGGTGTTCCTCACCCTGCGCG
ACGCCGTCGCCGACATCTCGGTGCCGGTGACCTGCTCGCGCACGCTGTTCGACGGCCTGAACCCGCCCCTGGTCGAGGGC
GCCAGCGTGGTCCTGCACGCGAAGCCGTCGTACTACGCCAACCGCGGCACGCTCTCGCTGTACGCCCGCGAGATCCGCAT
GGTCGGCCTGGGCGAGCTGCTCGCCCGGCTCGAGCGACGGCGCCAGCTGCTGGCTGCCGAGGGACTCTTCGCCGCCGAGC
TCAAGCGACCGCTGCCGTTCCTGCCCGGCACCGTCGGCCTGGTCACCGCCCCCAACAGCGCCGCCGAGCGCGACGTGCTC
GAGAACGCCCGCCGCCGGTGGCCCGCCGTCGCCTTCGAGATCGCGTACGCCGCGATGCAGGGGCCGCGGTCGGCCAGCGA
GGTGATCGAGGCGGTCGAGCGCCTCGACCGTGATCCGGCGGTCGAGGTGATCGTGGTCGCCCGGGGCGGCGGCTCGGTCG
AGGACCTGCTGCCGTTCTCCGACGAGGCGCTGATCCGCGCGGTGCACCGGATCCGCACGCCGCTGGTCTCCGCGATCGGC
CACGAGCCCGACTCCCCGCTGCTCGACCTGGTCGCCGATGTCCGCGCCTCGACGCCCACGGATGCCGCCAAGCTCGTGGT
CCCGGACGTGGCCGAGGAGCAGCGCAACGTGCGCCGTGCCCGGGAGCGGGCGCGCGGCGCACTGGCCAGGTGGATCGCCC
GGGAACAGGCGGGCCTCGACGGGCTCCGCTCCCGGCCGGCGCTGGCCGACCCGCGGATGCTCCTCGACGCCCGGCGCGAC
GAGGTCGACCAGCTGCGCGACCGGGCCCGGCGCTGCCTGGGCCACGCGCTGGACCGGGCGGCCGACGACATCGGCCACCA
CCGGGCCCGCGCCCGGGCGCTGTCCCCGCTGGCCACCCTGCAACGCGGGTACGCCGTGCTCCAGGACGCCGACGGCCACG
TGGTCACCTCGGTCGGTGCCGTCGCGCCGAAGCAGCAGGTCAGCGTGCGCGTCGCCGACGGCCGGATCCACGCCACCACC
ACCAGCACCGAGGAGCTCGATGTCCAAGAAGGCTGA

Upstream 100 bases:

>100_bases
GGCCCGGTGCCCGAGACTGGCCATGCCCCGGCCCCGGCCCCGGGCCCGGGCCCATCGTGGAAGAAGCAGTCTGTCGGCGC
TGCTCGGTAGGGTCCCGGCC

Downstream 100 bases:

>100_bases
GCCGGACCAGACCCCGTCGTACGAAGCGGCCCGCGAGGAGCTGGTCGAGGTGGTCCGCCGCCTCGAGACCGGCGGCACCA
CGCTCGAGGAGTCGCTGGCG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MALESSLESPAPVRQIANAIAGWVDRLGAVWVEGQVAQVSRRPGLNTVFLTLRDAVADISVPVTCSRTLFDGLNPPLVEG
ASVVLHAKPSYYANRGTLSLYAREIRMVGLGELLARLERRRQLLAAEGLFAAELKRPLPFLPGTVGLVTAPNSAAERDVL
ENARRRWPAVAFEIAYAAMQGPRSASEVIEAVERLDRDPAVEVIVVARGGGSVEDLLPFSDEALIRAVHRIRTPLVSAIG
HEPDSPLLDLVADVRASTPTDAAKLVVPDVAEEQRNVRRARERARGALARWIAREQAGLDGLRSRPALADPRMLLDARRD
EVDQLRDRARRCLGHALDRAADDIGHHRARARALSPLATLQRGYAVLQDADGHVVTSVGAVAPKQQVSVRVADGRIHATT
TSTEELDVQEG

Sequences:

>Translated_411_residues
MALESSLESPAPVRQIANAIAGWVDRLGAVWVEGQVAQVSRRPGLNTVFLTLRDAVADISVPVTCSRTLFDGLNPPLVEG
ASVVLHAKPSYYANRGTLSLYAREIRMVGLGELLARLERRRQLLAAEGLFAAELKRPLPFLPGTVGLVTAPNSAAERDVL
ENARRRWPAVAFEIAYAAMQGPRSASEVIEAVERLDRDPAVEVIVVARGGGSVEDLLPFSDEALIRAVHRIRTPLVSAIG
HEPDSPLLDLVADVRASTPTDAAKLVVPDVAEEQRNVRRARERARGALARWIAREQAGLDGLRSRPALADPRMLLDARRD
EVDQLRDRARRCLGHALDRAADDIGHHRARARALSPLATLQRGYAVLQDADGHVVTSVGAVAPKQQVSVRVADGRIHATT
TSTEELDVQEG
>Mature_410_residues
ALESSLESPAPVRQIANAIAGWVDRLGAVWVEGQVAQVSRRPGLNTVFLTLRDAVADISVPVTCSRTLFDGLNPPLVEGA
SVVLHAKPSYYANRGTLSLYAREIRMVGLGELLARLERRRQLLAAEGLFAAELKRPLPFLPGTVGLVTAPNSAAERDVLE
NARRRWPAVAFEIAYAAMQGPRSASEVIEAVERLDRDPAVEVIVVARGGGSVEDLLPFSDEALIRAVHRIRTPLVSAIGH
EPDSPLLDLVADVRASTPTDAAKLVVPDVAEEQRNVRRARERARGALARWIAREQAGLDGLRSRPALADPRMLLDARRDE
VDQLRDRARRCLGHALDRAADDIGHHRARARALSPLATLQRGYAVLQDADGHVVTSVGAVAPKQQVSVRVADGRIHATTT
STEELDVQEG

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=427, Percent_Identity=29.03981264637, Blast_Score=175, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_NOCSJ (A1SFK7)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_922279.1
- STRING:   A1SFK7
- GeneID:   4599554
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_1074
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   PWPVRTV
- ProtClustDB:   CLSK2783392
- BioCyc:   NSP35761:NOCA_1074-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 44534; Mature: 44403

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALESSLESPAPVRQIANAIAGWVDRLGAVWVEGQVAQVSRRPGLNTVFLTLRDAVADIS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCHHHHHHCCCCCCEEEEEHHHHHHHCC
VPVTCSRTLFDGLNPPLVEGASVVLHAKPSYYANRGTLSLYAREIRMVGLGELLARLERR
CCCEECHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQLLAAEGLFAAELKRPLPFLPGTVGLVTAPNSAAERDVLENARRRWPAVAFEIAYAAMQ
HHHHHHCCHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHC
GPRSASEVIEAVERLDRDPAVEVIVVARGGGSVEDLLPFSDEALIRAVHRIRTPLVSAIG
CCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHC
HEPDSPLLDLVADVRASTPTDAAKLVVPDVAEEQRNVRRARERARGALARWIAREQAGLD
CCCCCHHHHHHHHHHCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLRSRPALADPRMLLDARRDEVDQLRDRARRCLGHALDRAADDIGHHRARARALSPLATL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRGYAVLQDADGHVVTSVGAVAPKQQVSVRVADGRIHATTTSTEELDVQEG
HHHHHHEECCCCCEEEHHHCCCCCHHEEEEEECCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ALESSLESPAPVRQIANAIAGWVDRLGAVWVEGQVAQVSRRPGLNTVFLTLRDAVADIS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCHHHHHHCCCCCCEEEEEHHHHHHHCC
VPVTCSRTLFDGLNPPLVEGASVVLHAKPSYYANRGTLSLYAREIRMVGLGELLARLERR
CCCEECHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQLLAAEGLFAAELKRPLPFLPGTVGLVTAPNSAAERDVLENARRRWPAVAFEIAYAAMQ
HHHHHHCCHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHC
GPRSASEVIEAVERLDRDPAVEVIVVARGGGSVEDLLPFSDEALIRAVHRIRTPLVSAIG
CCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHC
HEPDSPLLDLVADVRASTPTDAAKLVVPDVAEEQRNVRRARERARGALARWIAREQAGLD
CCCCCHHHHHHHHHHCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLRSRPALADPRMLLDARRDEVDQLRDRARRCLGHALDRAADDIGHHRARARALSPLATL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRGYAVLQDADGHVVTSVGAVAPKQQVSVRVADGRIHATTTSTEELDVQEG
HHHHHHEECCCCCEEEHHHCCCCCHHEEEEEECCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA