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The map label for this gene is yngJ [H]

Identifier: 119715103

GI number: 119715103

Start: 895420

End: 896580

Strand: Direct

Name: yngJ [H]

Synonym: Noca_0858

Alternate gene names: 119715103

Gene position: 895420-896580 (Clockwise)

Preceding gene: 119715102

Following gene: 119715104

Centisome position: 17.96

GC content: 69.42

Gene sequence:

>1161_bases
GTGACCGAGGACATGACCGATTCCGACCAGCTGCGGGAGTTCGTGCGCCAGAGCGTGCGCGCTTTCGTGCACAAGGAGTG
CGACGAGTGGCGTTGCCTCGAGTGGGACAAGGCAGGTACCTACCCGAAGGAGGTGTTCGACCAGATCGCCGACCTCGGGT
GGTACGGCATCGGCATCCCCGACGAGCTCGGCGGCTCGGGTGGCACCGCCAGCGACCTGCTCGTGGTCGCTGAGGAGCTC
GGGCGCGGGAGCACCGACCTGGTGGCGTGCTTCAGCCTCACCGCCTCCGGACTGCGCACGATCGTCACCGACGGCTCCGA
CGTCCAGAAGGCCGAGCTGATCCCGGCCATCATGAGTGGCCGGACCCGACTCTCCATCGCCGTCACCGAGCCCGAAGCGG
GCTCCGACGCGGCGAGCCTGCTCACCTCGGCTCGGCGAGACGGAGACCACTACGTCCTGAACGGCCAGAAGACCTTCTGC
GAGGCGGCCGGGCTCCCCGACACGATCGTGCAGCTCTACGCCCGGACCGACCCGGCGGCCCGCAAGCAGGACGGGATCAG
CATGATCCTCCTCGACCCGACCCTGCCCGGCGTCACGCTGCGCCGCCTGCCCACCATGGGACGCAACATCACCGGCGTCT
ACGAGGTCTTCCTCGACGACGTCCGGGTGCCGGTCGATCGGCTCGTCGGCGTCGAGAACAACGGCTGGCGCCAGCTCGGC
GCCGAGCTCCCGCTCGAGCGCCTGATCATCAGCGCCGGCTTCGTCGGCGCCACCCTGCAGGTCCTCGAGGACACCCTGCA
GCACGTCAAGGAGCGCGAGCAGTTCGGCCGGGCGATCGGTGACTTCCAGGCCGTCGCCCACCTGCTCGTGGACCTCTACA
CGCGTGTCGAGAGCGTCCGGCTGCTGGTCTACCGCGGCGGTGAGCTCCACGACGCCGGACAGCCGCACACCAAGGAGGCG
TCGATGGCGAAGATCGCCTCCGCGGAGCTCTACGCCGACGCTGCGCGGTACTGCATGCAGCTGCACGGTGGCTACGGCTA
CGTCGACGAGCACCCGCTGACGATGCACTACGTCGATGCGGTCATCGCGACCGTCGCCGGTGGGGCCTCGCAGGTGCAGC
GCAACATCGTGGCCCGCGAGCTCGGCCTGAAGCCGCGGTGA

Upstream 100 bases:

>100_bases
CGAGCCCGCGCTCGTCGGTCGCCCACGTCAAGCAGGTGCTGAGGCGGGGTTCGCCCCACGACCTCACGCCGCCCCCCGAG
TACGCCTGGATTGAGGAGAA

Downstream 100 bases:

>100_bases
TCGCGATGATGGCACTCGAAGGCGTCAAGGTCCTCGACGCGGCGTCGATGCTCGCCGGACCCTACTGCGCGACCCTGCTC
GGGGACCTGGGCGCGGACGT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTEDMTDSDQLREFVRQSVRAFVHKECDEWRCLEWDKAGTYPKEVFDQIADLGWYGIGIPDELGGSGGTASDLLVVAEEL
GRGSTDLVACFSLTASGLRTIVTDGSDVQKAELIPAIMSGRTRLSIAVTEPEAGSDAASLLTSARRDGDHYVLNGQKTFC
EAAGLPDTIVQLYARTDPAARKQDGISMILLDPTLPGVTLRRLPTMGRNITGVYEVFLDDVRVPVDRLVGVENNGWRQLG
AELPLERLIISAGFVGATLQVLEDTLQHVKEREQFGRAIGDFQAVAHLLVDLYTRVESVRLLVYRGGELHDAGQPHTKEA
SMAKIASAELYADAARYCMQLHGGYGYVDEHPLTMHYVDAVIATVAGGASQVQRNIVARELGLKPR

Sequences:

>Translated_386_residues
MTEDMTDSDQLREFVRQSVRAFVHKECDEWRCLEWDKAGTYPKEVFDQIADLGWYGIGIPDELGGSGGTASDLLVVAEEL
GRGSTDLVACFSLTASGLRTIVTDGSDVQKAELIPAIMSGRTRLSIAVTEPEAGSDAASLLTSARRDGDHYVLNGQKTFC
EAAGLPDTIVQLYARTDPAARKQDGISMILLDPTLPGVTLRRLPTMGRNITGVYEVFLDDVRVPVDRLVGVENNGWRQLG
AELPLERLIISAGFVGATLQVLEDTLQHVKEREQFGRAIGDFQAVAHLLVDLYTRVESVRLLVYRGGELHDAGQPHTKEA
SMAKIASAELYADAARYCMQLHGGYGYVDEHPLTMHYVDAVIATVAGGASQVQRNIVARELGLKPR
>Mature_385_residues
TEDMTDSDQLREFVRQSVRAFVHKECDEWRCLEWDKAGTYPKEVFDQIADLGWYGIGIPDELGGSGGTASDLLVVAEELG
RGSTDLVACFSLTASGLRTIVTDGSDVQKAELIPAIMSGRTRLSIAVTEPEAGSDAASLLTSARRDGDHYVLNGQKTFCE
AAGLPDTIVQLYARTDPAARKQDGISMILLDPTLPGVTLRRLPTMGRNITGVYEVFLDDVRVPVDRLVGVENNGWRQLGA
ELPLERLIISAGFVGATLQVLEDTLQHVKEREQFGRAIGDFQAVAHLLVDLYTRVESVRLLVYRGGELHDAGQPHTKEAS
MAKIASAELYADAARYCMQLHGGYGYVDEHPLTMHYVDAVIATVAGGASQVQRNIVARELGLKPR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=372, Percent_Identity=33.6021505376344, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=30, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI226958414, Length=345, Percent_Identity=31.0144927536232, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI4501859, Length=384, Percent_Identity=28.6458333333333, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI7656849, Length=350, Percent_Identity=30.8571428571429, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=30.9973045822102, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=29.2553191489362, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=29.2553191489362, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI21361497, Length=368, Percent_Identity=25.8152173913043, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI4557235, Length=342, Percent_Identity=28.9473684210526, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI76496475, Length=342, Percent_Identity=28.9473684210526, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI38505218, Length=387, Percent_Identity=25.3229974160207, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI211971008, Length=338, Percent_Identity=26.3313609467456, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI48976061, Length=338, Percent_Identity=26.3313609467456, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4503943, Length=389, Percent_Identity=23.9074550128535, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI7669494, Length=367, Percent_Identity=24.5231607629428, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786223, Length=371, Percent_Identity=28.0323450134771, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI87081958, Length=372, Percent_Identity=25.5376344086022, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=28.6096256684492, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17570075, Length=372, Percent_Identity=30.3763440860215, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=29.144385026738, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17569725, Length=351, Percent_Identity=28.4900284900285, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17508101, Length=349, Percent_Identity=29.7994269340974, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=28.0323450134771, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17534899, Length=354, Percent_Identity=30.225988700565, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=363, Percent_Identity=31.129476584022, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI71985192, Length=303, Percent_Identity=31.6831683168317, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71990804, Length=295, Percent_Identity=27.7966101694915, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17551932, Length=372, Percent_Identity=26.6129032258064, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17505929, Length=353, Percent_Identity=25.4957507082153, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=28.8793103448276, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=28.2157676348548, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17534353, Length=384, Percent_Identity=27.8645833333333, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=26.1818181818182, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=330, Percent_Identity=24.5454545454545, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531913, Length=175, Percent_Identity=26.8571428571429, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=29.5698924731183, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24666513, Length=339, Percent_Identity=31.5634218289086, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=29.023746701847, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI21355753, Length=386, Percent_Identity=27.2020725388601, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=28.5714285714286, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281363737, Length=342, Percent_Identity=26.3157894736842, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI19920834, Length=377, Percent_Identity=25.4641909814324, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42115; Mature: 41984

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDMTDSDQLREFVRQSVRAFVHKECDEWRCLEWDKAGTYPKEVFDQIADLGWYGIGIP
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCEECCCCC
DELGGSGGTASDLLVVAEELGRGSTDLVACFSLTASGLRTIVTDGSDVQKAELIPAIMSG
HHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCC
RTRLSIAVTEPEAGSDAASLLTSARRDGDHYVLNGQKTFCEAAGLPDTIVQLYARTDPAA
CCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCHHHHHHHHCCCCCC
RKQDGISMILLDPTLPGVTLRRLPTMGRNITGVYEVFLDDVRVPVDRLVGVENNGWRQLG
HHCCCCEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHH
AELPLERLIISAGFVGATLQVLEDTLQHVKEREQFGRAIGDFQAVAHLLVDLYTRVESVR
HHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LLVYRGGELHDAGQPHTKEASMAKIASAELYADAARYCMQLHGGYGYVDEHPLTMHYVDA
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VIATVAGGASQVQRNIVARELGLKPR
HHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEDMTDSDQLREFVRQSVRAFVHKECDEWRCLEWDKAGTYPKEVFDQIADLGWYGIGIP
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCEECCCCC
DELGGSGGTASDLLVVAEELGRGSTDLVACFSLTASGLRTIVTDGSDVQKAELIPAIMSG
HHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCC
RTRLSIAVTEPEAGSDAASLLTSARRDGDHYVLNGQKTFCEAAGLPDTIVQLYARTDPAA
CCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCHHHHHHHHCCCCCC
RKQDGISMILLDPTLPGVTLRRLPTMGRNITGVYEVFLDDVRVPVDRLVGVENNGWRQLG
HHCCCCEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHH
AELPLERLIISAGFVGATLQVLEDTLQHVKEREQFGRAIGDFQAVAHLLVDLYTRVESVR
HHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LLVYRGGELHDAGQPHTKEASMAKIASAELYADAARYCMQLHGGYGYVDEHPLTMHYVDA
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VIATVAGGASQVQRNIVARELGLKPR
HHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]