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The map label for this gene is alsR [H]

Identifier: 119715079

GI number: 119715079

Start: 875971

End: 876963

Strand: Direct

Name: alsR [H]

Synonym: Noca_0834

Alternate gene names: 119715079

Gene position: 875971-876963 (Clockwise)

Preceding gene: 119715078

Following gene: 119715080

Centisome position: 17.57

GC content: 70.9

Gene sequence:

>993_bases
ATGGATAAGTTTCCGTACGGTCAGGTGACGCCCATCACAGCCGATGGGCGGGACCCGGTCGAAAGTGCTGCCATGGAACT
GCGCCATCTTCGATACTTCACGGCGGTAGCCGAGACCTGCCACTTCGGACAGGCAGCAGAGCGCCTGTTGATCGCCCAGC
CGGCGCTGTCGCAGGCGATCCGGTCGTTGGAGTCCGAGCTCGGGGTCACGCTGTTCACGCGCACCACTCGGCACGTCGCA
CTGACGCCCGCGGGGGAGTACTTCTTCGACGAGAGCCGCCGGATCCTGGCCGCCGTGGAGGACAGCACCCGCGGGGTGCG
CCAGCTGGCCGACGGCCGCCACGGGTTGGTGCGGCTGGGGCTGGTGGGTACGGCGGCGACCTCGCACCTGCCGCACCTCG
TCCGGACCTTGAAGCGGGAGCTGCCCGAGGTCGCGGTGGACGTGAAGGCCGACATCCTCACCCCCGAGCTCTGCGACCTG
CTCCGCGCCGGCGCCATCGACGTCGCCGTGCTGCGACCACCGGTCGTAGGGGAGGGGATCGAGATCCACGTCGTCGAGGA
GGAGCCGCTCATCCTCGCCCTCCCCGAGAGCCACGCGCTGGCCGCCCGGGGCGACCTCGGCGTGGAGGACCTGCGCAACG
AGCCGTTCATCAGCTATGCGGCGCAGGAGTCTGCGGTCAACCAGGCCGTTCTCCGTGCGTGCCGCACCGCCGACTTCGTG
CCCCACCGCTCGCACGAGGCGCCTGGCACCGCGGTCCTGCTCTCCCTGGTGGCGGCGGGCCTGGGCGTCTCGCTGGTTCC
CGCCTCGGTGCGAGCGTTCCCGCTGACCGGCGTCGTGTTCCGTGAGGTCCTCGACGCCGGGACCATCCAGCTGGCGCTGG
CCTGGCGCAGCGACCGGCCGCGCCCGGTGGTGACGATGGTGGTCTCCGTCCTCGCCGCCGACGACGCCCTGGCGTCGCTG
TCGAGCAGCTTCGTCGACGGGATCCTCGCATGA

Upstream 100 bases:

>100_bases
GTGGCTGCGACCCCGGTGGCTCGGGTGACGACGCGGAGCGAGCCCTCGAACATTGATCGGACGAACTGATGAATCCTCCG
CAGATTGGTACTTGTGTGTG

Downstream 100 bases:

>100_bases
AGATCACCAGGGTCGAGGCGGTCCCCTACGCGATCCCGTACGTCAAGCCGCTGCGCTTCGCCAGCGGCGAGGTGCACGTC
GCCGAACACGTCCTGGTGCG

Product: substrate-binding protein LysR

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDKFPYGQVTPITADGRDPVESAAMELRHLRYFTAVAETCHFGQAAERLLIAQPALSQAIRSLESELGVTLFTRTTRHVA
LTPAGEYFFDESRRILAAVEDSTRGVRQLADGRHGLVRLGLVGTAATSHLPHLVRTLKRELPEVAVDVKADILTPELCDL
LRAGAIDVAVLRPPVVGEGIEIHVVEEEPLILALPESHALAARGDLGVEDLRNEPFISYAAQESAVNQAVLRACRTADFV
PHRSHEAPGTAVLLSLVAAGLGVSLVPASVRAFPLTGVVFREVLDAGTIQLALAWRSDRPRPVVTMVVSVLAADDALASL
SSSFVDGILA

Sequences:

>Translated_330_residues
MDKFPYGQVTPITADGRDPVESAAMELRHLRYFTAVAETCHFGQAAERLLIAQPALSQAIRSLESELGVTLFTRTTRHVA
LTPAGEYFFDESRRILAAVEDSTRGVRQLADGRHGLVRLGLVGTAATSHLPHLVRTLKRELPEVAVDVKADILTPELCDL
LRAGAIDVAVLRPPVVGEGIEIHVVEEEPLILALPESHALAARGDLGVEDLRNEPFISYAAQESAVNQAVLRACRTADFV
PHRSHEAPGTAVLLSLVAAGLGVSLVPASVRAFPLTGVVFREVLDAGTIQLALAWRSDRPRPVVTMVVSVLAADDALASL
SSSFVDGILA
>Mature_330_residues
MDKFPYGQVTPITADGRDPVESAAMELRHLRYFTAVAETCHFGQAAERLLIAQPALSQAIRSLESELGVTLFTRTTRHVA
LTPAGEYFFDESRRILAAVEDSTRGVRQLADGRHGLVRLGLVGTAATSHLPHLVRTLKRELPEVAVDVKADILTPELCDL
LRAGAIDVAVLRPPVVGEGIEIHVVEEEPLILALPESHALAARGDLGVEDLRNEPFISYAAQESAVNQAVLRACRTADFV
PHRSHEAPGTAVLLSLVAAGLGVSLVPASVRAFPLTGVVFREVLDAGTIQLALAWRSDRPRPVVTMVVSVLAADDALASL
SSSFVDGILA

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=274, Percent_Identity=33.9416058394161, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=31.6666666666667, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI2367136, Length=290, Percent_Identity=31.0344827586207, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1790399, Length=247, Percent_Identity=32.3886639676113, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693105, Length=275, Percent_Identity=26.9090909090909, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081904, Length=186, Percent_Identity=31.1827956989247, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788748, Length=280, Percent_Identity=27.8571428571429, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788297, Length=159, Percent_Identity=34.5911949685535, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787806, Length=257, Percent_Identity=28.4046692607004, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789639, Length=304, Percent_Identity=22.6973684210526, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790262, Length=264, Percent_Identity=24.2424242424242, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787530, Length=257, Percent_Identity=25.2918287937743, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789204, Length=264, Percent_Identity=26.5151515151515, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=252, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786713, Length=83, Percent_Identity=45.7831325301205, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=182, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787589, Length=140, Percent_Identity=35, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786508, Length=172, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786401, Length=149, Percent_Identity=28.8590604026846, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788296, Length=294, Percent_Identity=25.8503401360544, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35314; Mature: 35314

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFPYGQVTPITADGRDPVESAAMELRHLRYFTAVAETCHFGQAAERLLIAQPALSQAI
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RSLESELGVTLFTRTTRHVALTPAGEYFFDESRRILAAVEDSTRGVRQLADGRHGLVRLG
HHHHHHCCEEEEEECCCEEEECCCCHHHHCCCCEEEEEECHHHHHHHHHHCCCCCEEEEE
LVGTAATSHLPHLVRTLKRELPEVAVDVKADILTPELCDLLRAGAIDVAVLRPPVVGEGI
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCE
EIHVVEEEPLILALPESHALAARGDLGVEDLRNEPFISYAAQESAVNQAVLRACRTADFV
EEEEEECCCEEEECCCCCCEECCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
PHRSHEAPGTAVLLSLVAAGLGVSLVPASVRAFPLTGVVFREVLDAGTIQLALAWRSDRP
CCCCCCCCHHHHHHHHHHHCCCCEECCCCHHHCCCHHHHHHHHHCCCCEEEEEEECCCCC
RPVVTMVVSVLAADDALASLSSSFVDGILA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKFPYGQVTPITADGRDPVESAAMELRHLRYFTAVAETCHFGQAAERLLIAQPALSQAI
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RSLESELGVTLFTRTTRHVALTPAGEYFFDESRRILAAVEDSTRGVRQLADGRHGLVRLG
HHHHHHCCEEEEEECCCEEEECCCCHHHHCCCCEEEEEECHHHHHHHHHHCCCCCEEEEE
LVGTAATSHLPHLVRTLKRELPEVAVDVKADILTPELCDLLRAGAIDVAVLRPPVVGEGI
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCE
EIHVVEEEPLILALPESHALAARGDLGVEDLRNEPFISYAAQESAVNQAVLRACRTADFV
EEEEEECCCEEEECCCCCCEECCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
PHRSHEAPGTAVLLSLVAAGLGVSLVPASVRAFPLTGVVFREVLDAGTIQLALAWRSDRP
CCCCCCCCHHHHHHHHHHHCCCCEECCCCHHHCCCHHHHHHHHHCCCCEEEEEEECCCCC
RPVVTMVVSVLAADDALASLSSSFVDGILA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]