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The map label for this gene is moaCB [H]

Identifier: 119715040

GI number: 119715040

Start: 836847

End: 837323

Strand: Direct

Name: moaCB [H]

Synonym: Noca_0793

Alternate gene names: 119715040

Gene position: 836847-837323 (Clockwise)

Preceding gene: 119715039

Following gene: 119715041

Centisome position: 16.78

GC content: 75.47

Gene sequence:

>477_bases
GTGAGCCTGCGCGCCGAGGTCGTCGTCGCCTCCAACCGGGCCGCGGCCGGGGTCTACGAGGACACCACCGGCCCGCTGAT
CATCGACTTCCTGCGCGAGCTGGGCTTCACGGTCGACGCGCCCGTCGTCGTACCGGATGGCGAGCCGGTCGGCGCCGCGA
TCACCGCCGCCGTCGAGGGTGGTGCGCGGGTGGTGCTCACGACCGGCGGCACCGGCCTCACCCCGACCGACCGGACCCCC
GAGGTGACCCGGGCGCTGCTGGACGCCGAGATCCCCGGCATCGCGGAGGCGATCCGCGCGTACGGCGTCGCGCAGGGCGT
GCCTACAGCGGTGCTCTCGCGCGGGCTCGCCGGCGTGGTCGGCTCGTGCGTGGTCGTCAACCTCCCCGGCTCGCGCGGCG
GCGTGAAGGACGGGCTCGCCGTGCTCCGCCCGGTGCTGGTGCACGCCGCCGAGCAGGTCGTGGGGAGCGACCATTGA

Upstream 100 bases:

>100_bases
CCGTGGTCGACATGGTCAAGGCGGTCGACAAGGCCGCGGTGGTCACCGACATCCGGGTCGAGACGAAGACCGGCGGCAAG
TCCGGCGACTGGAGCCGGCC

Downstream 100 bases:

>100_bases
GGGTGTGGCCGGCCCGGCTGACCTCGGGGGAGGTCACGGTCCGGCCGCTCGCCGCCCGGGACGCGGCTGCCTGGCGGGAC
GCCCGGCGCCGCAACGTCGC

Product: molybdopterin adenylyltransferase

Products: NA

Alternate protein names: Molybdenum cofactor biosynthesis protein C; Molybdenum cofactor biosynthesis protein B [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSLRAEVVVASNRAAAGVYEDTTGPLIIDFLRELGFTVDAPVVVPDGEPVGAAITAAVEGGARVVLTTGGTGLTPTDRTP
EVTRALLDAEIPGIAEAIRAYGVAQGVPTAVLSRGLAGVVGSCVVVNLPGSRGGVKDGLAVLRPVLVHAAEQVVGSDH

Sequences:

>Translated_158_residues
MSLRAEVVVASNRAAAGVYEDTTGPLIIDFLRELGFTVDAPVVVPDGEPVGAAITAAVEGGARVVLTTGGTGLTPTDRTP
EVTRALLDAEIPGIAEAIRAYGVAQGVPTAVLSRGLAGVVGSCVVVNLPGSRGGVKDGLAVLRPVLVHAAEQVVGSDH
>Mature_157_residues
SLRAEVVVASNRAAAGVYEDTTGPLIIDFLRELGFTVDAPVVVPDGEPVGAAITAAVEGGARVVLTTGGTGLTPTDRTPE
VTRALLDAEIPGIAEAIRAYGVAQGVPTAVLSRGLAGVVGSCVVVNLPGSRGGVKDGLAVLRPVLVHAAEQVVGSDH

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=155, Percent_Identity=33.5483870967742, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI10880983, Length=155, Percent_Identity=33.5483870967742, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786190, Length=143, Percent_Identity=33.5664335664336, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1787000, Length=135, Percent_Identity=31.8518518518519, Blast_Score=64, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=162, Percent_Identity=34.5679012345679, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136978, Length=95, Percent_Identity=44.2105263157895, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24638841, Length=95, Percent_Identity=44.2105263157895, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR020817
- InterPro:   IPR012247
- InterPro:   IPR008284
- InterPro:   IPR001453
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC; PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 15813; Mature: 15682

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRAEVVVASNRAAAGVYEDTTGPLIIDFLRELGFTVDAPVVVPDGEPVGAAITAAVEG
CCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEECC
GARVVLTTGGTGLTPTDRTPEVTRALLDAEIPGIAEAIRAYGVAQGVPTAVLSRGLAGVV
CCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHC
GSCVVVNLPGSRGGVKDGLAVLRPVLVHAAEQVVGSDH
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLRAEVVVASNRAAAGVYEDTTGPLIIDFLRELGFTVDAPVVVPDGEPVGAAITAAVEG
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEECC
GARVVLTTGGTGLTPTDRTPEVTRALLDAEIPGIAEAIRAYGVAQGVPTAVLSRGLAGVV
CCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHC
GSCVVVNLPGSRGGVKDGLAVLRPVLVHAAEQVVGSDH
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9495759 [H]