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The map label for this gene is moaC

Identifier: 119715039

GI number: 119715039

Start: 836359

End: 836850

Strand: Direct

Name: moaC

Synonym: Noca_0792

Alternate gene names: 119715039

Gene position: 836359-836850 (Clockwise)

Preceding gene: 119715038

Following gene: 119715040

Centisome position: 16.77

GC content: 72.76

Gene sequence:

>492_bases
ATGTCCGATTCGCCCCGGCGGCTCACCCACGTCGACGAGTCCGGGGCGGCCCGGATGGTCGACGTCTCCGGCAAGGACGT
CACCGCCCGCACGGCGACCGCTTCCGGCCGGGTGCTGGTCTCGGAGACGGTCGTCGGACTGCTCCGCGGCGAGGGCGTGC
CGAAGGGCGACGCGCTCGGGGTGGCCCGGGTCGCCGGGATCATGGCCGCCAAGCAGACGCCGACCCTGATCCCGCTGTGC
CACCCGCTCTCGATCTCGGGGGTGAGCGTCGACCTCGAGGTGACCGACGACCCCGAGCCGAGCGTGGCGATCCGCGCGAC
GGTCAAGACGACCGACCGCACCGGCGTGGAGATGGAGGCGCTGACCGCGGTCTCGGTCGCCGCCCTCACCGTGGTCGACA
TGGTCAAGGCGGTCGACAAGGCCGCGGTGGTCACCGACATCCGGGTCGAGACGAAGACCGGCGGCAAGTCCGGCGACTGG
AGCCGGCCGTGA

Upstream 100 bases:

>100_bases
TGGCATCCTCCGACGCGCTGGTCGTCGTGCCGGCGGACGTCACCTCCGTCGAGGCCGGCGAGCAGGTCCAGGTCCTGAGG
CTCGACGAGGAGTTCTGACG

Downstream 100 bases:

>100_bases
GCCTGCGCGCCGAGGTCGTCGTCGCCTCCAACCGGGCCGCGGCCGGGGTCTACGAGGACACCACCGGCCCGCTGATCATC
GACTTCCTGCGCGAGCTGGG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MSDSPRRLTHVDESGAARMVDVSGKDVTARTATASGRVLVSETVVGLLRGEGVPKGDALGVARVAGIMAAKQTPTLIPLC
HPLSISGVSVDLEVTDDPEPSVAIRATVKTTDRTGVEMEALTAVSVAALTVVDMVKAVDKAAVVTDIRVETKTGGKSGDW
SRP

Sequences:

>Translated_163_residues
MSDSPRRLTHVDESGAARMVDVSGKDVTARTATASGRVLVSETVVGLLRGEGVPKGDALGVARVAGIMAAKQTPTLIPLC
HPLSISGVSVDLEVTDDPEPSVAIRATVKTTDRTGVEMEALTAVSVAALTVVDMVKAVDKAAVVTDIRVETKTGGKSGDW
SRP
>Mature_162_residues
SDSPRRLTHVDESGAARMVDVSGKDVTARTATASGRVLVSETVVGLLRGEGVPKGDALGVARVAGIMAAKQTPTLIPLCH
PLSISGVSVDLEVTDDPEPSVAIRATVKTTDRTGVEMEALTAVSVAALTVVDMVKAVDKAAVVTDIRVETKTGGKSGDWS
RP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=51.2820512820513, Blast_Score=136, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=43.7086092715232, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28574490, Length=156, Percent_Identity=51.9230769230769, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=51.3888888888889, Blast_Score=126, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_NOCSJ (A1SET2)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_922004.1
- ProteinModelPortal:   A1SET2
- SMR:   A1SET2
- STRING:   A1SET2
- GeneID:   4598873
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_0792
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   A1SET2
- ProtClustDB:   PRK09364
- BioCyc:   NSP35761:NOCA_0792-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16803; Mature: 16672

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: ACT_SITE 133-133

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSPRRLTHVDESGAARMVDVSGKDVTARTATASGRVLVSETVVGLLRGEGVPKGDALG
CCCCCCCEEECCCCCCEEEEEECCCCEEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCHH
VARVAGIMAAKQTPTLIPLCHPLSISGVSVDLEVTDDPEPSVAIRATVKTTDRTGVEMEA
HHHHHHHHHCCCCCCEEEEECCCEECCEEEEEEECCCCCCCEEEEEEEEECCCCCCCHHH
LTAVSVAALTVVDMVKAVDKAAVVTDIRVETKTGGKSGDWSRP
HHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SDSPRRLTHVDESGAARMVDVSGKDVTARTATASGRVLVSETVVGLLRGEGVPKGDALG
CCCCCCEEECCCCCCEEEEEECCCCEEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCHH
VARVAGIMAAKQTPTLIPLCHPLSISGVSVDLEVTDDPEPSVAIRATVKTTDRTGVEMEA
HHHHHHHHHCCCCCCEEEEECCCEECCEEEEEEECCCCCCCEEEEEEEEECCCCCCCHHH
LTAVSVAALTVVDMVKAVDKAAVVTDIRVETKTGGKSGDWSRP
HHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA