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The map label for this gene is bioI [H]

Identifier: 119714776

GI number: 119714776

Start: 543868

End: 545064

Strand: Reverse

Name: bioI [H]

Synonym: Noca_0512

Alternate gene names: 119714776

Gene position: 545064-543868 (Counterclockwise)

Preceding gene: 119714777

Following gene: 119714771

Centisome position: 10.93

GC content: 72.26

Gene sequence:

>1197_bases
ATGACCTACTTCGATCTCTCCGACCCGGCGTTCGACGTGACGTCCGCACAGGTCCACGCAGCCCGCGACCAGGACTGGTA
CGTCGAGACCAACTGGGGCTGGGCCGTGCTGCGCTACGCGGAGGTCAGCGCGCTCCTGCGCGACCGGCGGTTCCGGCAGG
GCAACGCCCGCTGGCCGGCGCAGAACGGGATCCACTCGGGGCTGTTCTCCGACTGGTGGCAGGAGACCCTGCTCAGCCTG
GAGGGCGACGACCACGCCCGGATCCGACGGCTGCTGATGCCGGCGTTCCGGAACAAGACGATCGCGGCGATGCGGCCCCG
GTTCCAGGCGCTGGCCAACGAGCTGATCGACGGCTTCGCCGACCGCGGGTCCGTGGAGTTCGTGAGCGAGTTCGCCGAGC
CGTATGCCGCGCGCATCATCTGCGTGCTCCTCGGCCTCCCGGAGGACCACTGGCAGCAGGTCGCGCACTGGGCCGACGAC
CTGGGCGCGTCGTTCTCCATCGACGTCGGCAACCAGGTGCCGCGGATCGAGGCGGCGCTGGACGGCCTCTACGGGTACGT
CGACGAGGTGGTCGCCGACCGGGCCGCGCACCCGCGCGAGGACCTCGTGACCACCCTCGTGCAGGCCACCGCCGACGGCG
ACCGCCTCTCGCGCCACGAGCTGGGGGTGGCCCTGGTGTTCCTCGCCTTCGCCGGCATGGAGACGACCCGCAACCAGCTC
GGCCTCGCCGTCCAGACGCTGCTCGAGCACCCCGACCAGTGGCGGCTCCTGGGCGAGCACCCGGAGCTCGGCGAGAACGC
GGTCGAGGAGGTGATGCGGGTCAACCCGACGGTGACCTGGGTGACCCGGGAGGCCCTGGAGGACGTGGAGCTCCAGGGCC
TGCGAATCCCGAAGGGTGGCATCGTGCAGATGCTCTCGCACAGCGCCGGCACCGACCCGGCGGCGATGCCGGACCCGTCC
TTCGACATCACCCAGCAGCGGCCGCCGCACCACGGGTTCGGCGCGGGGGTGCACCACTGCCTCGGGCACTTCGTCGCCCG
CACCGACATGGCCGTGGCGCTGCCGCTGCTGGCCCGCCGGATGCCCGGCGCCGAGCCCGACGGGCCGGGCAGGTGGCTGC
CGATCTCCGGCAACACCGGGGCGCTGAGCTTCCCGATCCGGTTCGAGCACCCGGCGCCGATCGGGTCGTGTGCCTGA

Upstream 100 bases:

>100_bases
CGACACCTGCGAGATCCGGATGGTGCGCCCGACCAACCCGTGAGTCCGCACGGCTGCGCCGCTAGGCTCCTCCGACACCC
GATCGCGAGGGGGCACCCGG

Downstream 100 bases:

>100_bases
GAACGCGCCATGGAGCGTGCTCAGGCACACGACCCGCCAGCCGGCGACACCTCCGCCTCATGCCGTCAGGTGGTGGAGGT
AGCACCAGCGCCAGTCCTCG

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTYFDLSDPAFDVTSAQVHAARDQDWYVETNWGWAVLRYAEVSALLRDRRFRQGNARWPAQNGIHSGLFSDWWQETLLSL
EGDDHARIRRLLMPAFRNKTIAAMRPRFQALANELIDGFADRGSVEFVSEFAEPYAARIICVLLGLPEDHWQQVAHWADD
LGASFSIDVGNQVPRIEAALDGLYGYVDEVVADRAAHPREDLVTTLVQATADGDRLSRHELGVALVFLAFAGMETTRNQL
GLAVQTLLEHPDQWRLLGEHPELGENAVEEVMRVNPTVTWVTREALEDVELQGLRIPKGGIVQMLSHSAGTDPAAMPDPS
FDITQQRPPHHGFGAGVHHCLGHFVARTDMAVALPLLARRMPGAEPDGPGRWLPISGNTGALSFPIRFEHPAPIGSCA

Sequences:

>Translated_398_residues
MTYFDLSDPAFDVTSAQVHAARDQDWYVETNWGWAVLRYAEVSALLRDRRFRQGNARWPAQNGIHSGLFSDWWQETLLSL
EGDDHARIRRLLMPAFRNKTIAAMRPRFQALANELIDGFADRGSVEFVSEFAEPYAARIICVLLGLPEDHWQQVAHWADD
LGASFSIDVGNQVPRIEAALDGLYGYVDEVVADRAAHPREDLVTTLVQATADGDRLSRHELGVALVFLAFAGMETTRNQL
GLAVQTLLEHPDQWRLLGEHPELGENAVEEVMRVNPTVTWVTREALEDVELQGLRIPKGGIVQMLSHSAGTDPAAMPDPS
FDITQQRPPHHGFGAGVHHCLGHFVARTDMAVALPLLARRMPGAEPDGPGRWLPISGNTGALSFPIRFEHPAPIGSCA
>Mature_397_residues
TYFDLSDPAFDVTSAQVHAARDQDWYVETNWGWAVLRYAEVSALLRDRRFRQGNARWPAQNGIHSGLFSDWWQETLLSLE
GDDHARIRRLLMPAFRNKTIAAMRPRFQALANELIDGFADRGSVEFVSEFAEPYAARIICVLLGLPEDHWQQVAHWADDL
GASFSIDVGNQVPRIEAALDGLYGYVDEVVADRAAHPREDLVTTLVQATADGDRLSRHELGVALVFLAFAGMETTRNQLG
LAVQTLLEHPDQWRLLGEHPELGENAVEEVMRVNPTVTWVTREALEDVELQGLRIPKGGIVQMLSHSAGTDPAAMPDPSF
DITQQRPPHHGFGAGVHHCLGHFVARTDMAVALPLLARRMPGAEPDGPGRWLPISGNTGALSFPIRFEHPAPIGSCA

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Drosophila melanogaster, GI24642101, Length=174, Percent_Identity=28.1609195402299, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 44093; Mature: 43962

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYFDLSDPAFDVTSAQVHAARDQDWYVETNWGWAVLRYAEVSALLRDRRFRQGNARWPA
CCEECCCCCCCCCCCHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
QNGIHSGLFSDWWQETLLSLEGDDHARIRRLLMPAFRNKTIAAMRPRFQALANELIDGFA
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DRGSVEFVSEFAEPYAARIICVLLGLPEDHWQQVAHWADDLGASFSIDVGNQVPRIEAAL
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHH
DGLYGYVDEVVADRAAHPREDLVTTLVQATADGDRLSRHELGVALVFLAFAGMETTRNQL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
GLAVQTLLEHPDQWRLLGEHPELGENAVEEVMRVNPTVTWVTREALEDVELQGLRIPKGG
HHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCEECCCCH
IVQMLSHSAGTDPAAMPDPSFDITQQRPPHHGFGAGVHHCLGHFVARTDMAVALPLLARR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPGAEPDGPGRWLPISGNTGALSFPIRFEHPAPIGSCA
CCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TYFDLSDPAFDVTSAQVHAARDQDWYVETNWGWAVLRYAEVSALLRDRRFRQGNARWPA
CEECCCCCCCCCCCHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
QNGIHSGLFSDWWQETLLSLEGDDHARIRRLLMPAFRNKTIAAMRPRFQALANELIDGFA
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DRGSVEFVSEFAEPYAARIICVLLGLPEDHWQQVAHWADDLGASFSIDVGNQVPRIEAAL
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHH
DGLYGYVDEVVADRAAHPREDLVTTLVQATADGDRLSRHELGVALVFLAFAGMETTRNQL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
GLAVQTLLEHPDQWRLLGEHPELGENAVEEVMRVNPTVTWVTREALEDVELQGLRIPKGG
HHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCEECCCCH
IVQMLSHSAGTDPAAMPDPSFDITQQRPPHHGFGAGVHHCLGHFVARTDMAVALPLLARR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MPGAEPDGPGRWLPISGNTGALSFPIRFEHPAPIGSCA
CCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]