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The map label for this gene is sigX [H]

Identifier: 119714753

GI number: 119714753

Start: 519078

End: 519878

Strand: Reverse

Name: sigX [H]

Synonym: Noca_0489

Alternate gene names: 119714753

Gene position: 519878-519078 (Counterclockwise)

Preceding gene: 119714754

Following gene: 119714752

Centisome position: 10.43

GC content: 71.79

Gene sequence:

>801_bases
ATGTCGTGGGAGGACACCGACGTCGCGCGCGGTCTCGACGCGCTGCGACGCCTCGTGGCCCACGTGCTTGTCCTGGAGCA
GCCCCAGCTCGCCGGGACACCCGGGATGCTCGCCACCGAGGCGGTCGCCAGCGGGCGCGCGGAGATGCGCGCGAAGACCC
GCCCCAAGAGCGGCCCCGGGACCGGCGACGGCGGTCCCGACGGGTACGGCGACGCGGAGCTCGCCACCTCCTCGGAGGAG
GACGAGGCCGAGCGGAGCCGGCTGATCGCGCTGGTGGAGCTGGCCCGCAAGGGCGACGCCGACGCCTTCGGCCTCCTCTA
CGACCACTACCAGCCCTCGGTCTACCGCTTCCTCTTCTACCGGACCCGGTCCGGCACCCTCGCCGAGGACCTGACCTCCG
AGACCTTCTTCCGCGCGTTGCGGAGCATGAACAACTTCCGCTGGCAGGGCAAGGACTTCGGCGCCTGGCTGATGACGATC
GCCCGCAACCTCGCGACCGACCACTTCAAGGCCGGCCGGACCCGCCTCGAGCTCACCACCGAGGACATGGGCCTGCACGA
CGACGCGACCGAGGGCCCGGAGTCGATGGTGCTCGCCGGGCTCACCAACGAGCTGCTGCTGCACGCCCTGACCGAGCTGC
CGCCCGAGCAGCGCGACTGCCTGGTGATGCGGTTCCTCCAGGGGATGAGCATCGCCGAGACGGCGGCCGTCCTGGGCCGC
AGCGACGGGGCCGTCAAGCAGCTCCAGCTGCGTGGGGTGCGCAACCTCGCGAAGCTGATGCCCGAGGGGATCCGGGACTG
A

Upstream 100 bases:

>100_bases
CGGACGCCGACGTCCTTTGAGCGGACAGAGGTTCCCAGCGGAGTAACTCACGTTTACGATGGGGCAGGCTTCGGGGGAAG
CTTCCGGGAGGATCGAACTC

Downstream 100 bases:

>100_bases
TGGGCACCCTCTTCGAAAACCTTTGCGCAGGGCGCCTCGCGCGCGTAACCCCGCCCGGCCACGCCTCGTTGAGGTCGGTG
TCAGAGTCCCCGAGCGGGGA

Product: sigma-70 region 2 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSWEDTDVARGLDALRRLVAHVLVLEQPQLAGTPGMLATEAVASGRAEMRAKTRPKSGPGTGDGGPDGYGDAELATSSEE
DEAERSRLIALVELARKGDADAFGLLYDHYQPSVYRFLFYRTRSGTLAEDLTSETFFRALRSMNNFRWQGKDFGAWLMTI
ARNLATDHFKAGRTRLELTTEDMGLHDDATEGPESMVLAGLTNELLLHALTELPPEQRDCLVMRFLQGMSIAETAAVLGR
SDGAVKQLQLRGVRNLAKLMPEGIRD

Sequences:

>Translated_266_residues
MSWEDTDVARGLDALRRLVAHVLVLEQPQLAGTPGMLATEAVASGRAEMRAKTRPKSGPGTGDGGPDGYGDAELATSSEE
DEAERSRLIALVELARKGDADAFGLLYDHYQPSVYRFLFYRTRSGTLAEDLTSETFFRALRSMNNFRWQGKDFGAWLMTI
ARNLATDHFKAGRTRLELTTEDMGLHDDATEGPESMVLAGLTNELLLHALTELPPEQRDCLVMRFLQGMSIAETAAVLGR
SDGAVKQLQLRGVRNLAKLMPEGIRD
>Mature_265_residues
SWEDTDVARGLDALRRLVAHVLVLEQPQLAGTPGMLATEAVASGRAEMRAKTRPKSGPGTGDGGPDGYGDAELATSSEED
EAERSRLIALVELARKGDADAFGLLYDHYQPSVYRFLFYRTRSGTLAEDLTSETFFRALRSMNNFRWQGKDFGAWLMTIA
RNLATDHFKAGRTRLELTTEDMGLHDDATEGPESMVLAGLTNELLLHALTELPPEQRDCLVMRFLQGMSIAETAAVLGRS
DGAVKQLQLRGVRNLAKLMPEGIRD

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=171, Percent_Identity=28.6549707602339, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 29256; Mature: 29125

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWEDTDVARGLDALRRLVAHVLVLEQPQLAGTPGMLATEAVASGRAEMRAKTRPKSGPG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCC
TGDGGPDGYGDAELATSSEEDEAERSRLIALVELARKGDADAFGLLYDHYQPSVYRFLFY
CCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHH
RTRSGTLAEDLTSETFFRALRSMNNFRWQGKDFGAWLMTIARNLATDHFKAGRTRLELTT
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
EDMGLHDDATEGPESMVLAGLTNELLLHALTELPPEQRDCLVMRFLQGMSIAETAAVLGR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCC
SDGAVKQLQLRGVRNLAKLMPEGIRD
CCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SWEDTDVARGLDALRRLVAHVLVLEQPQLAGTPGMLATEAVASGRAEMRAKTRPKSGPG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCC
TGDGGPDGYGDAELATSSEEDEAERSRLIALVELARKGDADAFGLLYDHYQPSVYRFLFY
CCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHH
RTRSGTLAEDLTSETFFRALRSMNNFRWQGKDFGAWLMTIARNLATDHFKAGRTRLELTT
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
EDMGLHDDATEGPESMVLAGLTNELLLHALTELPPEQRDCLVMRFLQGMSIAETAAVLGR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCC
SDGAVKQLQLRGVRNLAKLMPEGIRD
CCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8052622; 9393439 [H]