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The map label for this gene is trpS2 [H]

Identifier: 119714746

GI number: 119714746

Start: 512432

End: 513400

Strand: Reverse

Name: trpS2 [H]

Synonym: Noca_0482

Alternate gene names: 119714746

Gene position: 513400-512432 (Counterclockwise)

Preceding gene: 119714752

Following gene: 119714738

Centisome position: 10.3

GC content: 73.27

Gene sequence:

>969_bases
ATGCATCGCCAGCTCTCCCTGCTCACCCCCAGCGGCCACCTGACGCTCGGCAACCTGCTCGGCGCGCTCCGCCCGATGGC
TGCCGCGCAGCGCGACGCCAGCACACCGGCCGCGTGCTTCTACGGCATCGCCGACCTGCACGCGATGACCACGCCGCACG
AGCCGGCGCGGCTGCGGTCACTGACCCACGAGACCGCCACCCTCCTGCTCGCCGCCGGCCTCGAGGAGTCGACGCTGTTC
GTGCAGAGCCGGGTGCCGGCGCACGCCCAGCTCGCGTACCTGCTCGAGTGCACGGCGTCGACCGGCGAGCTGAACCGGAT
GATCCAGTTCAAGGAGAAGGGTCGCGACCAGCCGACGACCCGCGCGTCGTTGTTCACCTACCCGGCGCTGATGGCCGCGG
ACATCCTGCTCTACCGTCCGCGCCAGGTGCCGGTCGGCGCCGACCAGCGCCAGCACGTCGAGCTGACCCGGGACCTCGCG
ACCCGGTTCAACAGCACCTACGGCCCGGTGTTCACGATCCCGGAGATCACCGTCCCGGCGGCCGGCGCCCGGGTGATGCG
CCTGGACGACCCGACCGTGAAGATGGGCAAGTCCGCGGCCGAGACGCCGGGCGTGGTCCGGCTGCTCGACCCGCCGGACG
TCGTCCGCCGCAAGGTCGCCCGCGCCGTGACCGACTCCGACACCGGCCCGGACGCCGTGCGTGCCGACCCGAACAAGCCC
GGGGTGACGAACCTGCTGGAGATCCTCACCGCCTGCGGTGGCTCAGCGGAGGGCATCTCGACGTACGGCGCCCTCAAGAA
GGCGGTCGCCGACGCCGTCATCGCCGAGCTCGAGCCGCTCCAGAAGCGGTACGCCGACCTCGCGGCCGACCCGGCCCACG
TCACCAGCGTCTACGAGGCCGGCGCCGCCCGCTGCCGGGAGGTGACCGCCCCGGTGCTCGCGGCCGCGCAGGCCGCGATG
GGGCTGTGA

Upstream 100 bases:

>100_bases
CGAAGCACACCCACTTCACCCATCGGCCGCCCACGGGCGGCCGATTCTCGTCGGTCGAGCTGGTCGATCCGCCCGGGGCC
CGCACTCCCCAGGAGGATCC

Downstream 100 bases:

>100_bases
GGACGCGGGGTCGGCTGCTGGCAGCGGAGGGGCCGGTCAGCTGCCCTCGGCGAGCGCACGCGACCGGTCGCGCGCGGCCT
CCATGGCGGCGAGGAACGCG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase 2; TrpRS 2 [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MHRQLSLLTPSGHLTLGNLLGALRPMAAAQRDASTPAACFYGIADLHAMTTPHEPARLRSLTHETATLLLAAGLEESTLF
VQSRVPAHAQLAYLLECTASTGELNRMIQFKEKGRDQPTTRASLFTYPALMAADILLYRPRQVPVGADQRQHVELTRDLA
TRFNSTYGPVFTIPEITVPAAGARVMRLDDPTVKMGKSAAETPGVVRLLDPPDVVRRKVARAVTDSDTGPDAVRADPNKP
GVTNLLEILTACGGSAEGISTYGALKKAVADAVIAELEPLQKRYADLAADPAHVTSVYEAGAARCREVTAPVLAAAQAAM
GL

Sequences:

>Translated_322_residues
MHRQLSLLTPSGHLTLGNLLGALRPMAAAQRDASTPAACFYGIADLHAMTTPHEPARLRSLTHETATLLLAAGLEESTLF
VQSRVPAHAQLAYLLECTASTGELNRMIQFKEKGRDQPTTRASLFTYPALMAADILLYRPRQVPVGADQRQHVELTRDLA
TRFNSTYGPVFTIPEITVPAAGARVMRLDDPTVKMGKSAAETPGVVRLLDPPDVVRRKVARAVTDSDTGPDAVRADPNKP
GVTNLLEILTACGGSAEGISTYGALKKAVADAVIAELEPLQKRYADLAADPAHVTSVYEAGAARCREVTAPVLAAAQAAM
GL
>Mature_322_residues
MHRQLSLLTPSGHLTLGNLLGALRPMAAAQRDASTPAACFYGIADLHAMTTPHEPARLRSLTHETATLLLAAGLEESTLF
VQSRVPAHAQLAYLLECTASTGELNRMIQFKEKGRDQPTTRASLFTYPALMAADILLYRPRQVPVGADQRQHVELTRDLA
TRFNSTYGPVFTIPEITVPAAGARVMRLDDPTVKMGKSAAETPGVVRLLDPPDVVRRKVARAVTDSDTGPDAVRADPNKP
GVTNLLEILTACGGSAEGISTYGALKKAVADAVIAELEPLQKRYADLAADPAHVTSVYEAGAARCREVTAPVLAAAQAAM
GL

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=36.8580060422961, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=43.1818181818182, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1789786, Length=325, Percent_Identity=47.3846153846154, Blast_Score=268, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI71982800, Length=329, Percent_Identity=30.3951367781155, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71982793, Length=329, Percent_Identity=30.3951367781155, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=35.1744186046512, Blast_Score=199, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24666151, Length=328, Percent_Identity=34.7560975609756, Blast_Score=177, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 34277; Mature: 34277

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRQLSLLTPSGHLTLGNLLGALRPMAAAQRDASTPAACFYGIADLHAMTTPHEPARLRS
CCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
LTHETATLLLAAGLEESTLFVQSRVPAHAQLAYLLECTASTGELNRMIQFKEKGRDQPTT
HHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCH
RASLFTYPALMAADILLYRPRQVPVGADQRQHVELTRDLATRFNSTYGPVFTIPEITVPA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCEEECC
AGARVMRLDDPTVKMGKSAAETPGVVRLLDPPDVVRRKVARAVTDSDTGPDAVRADPNKP
CCCEEEEECCCHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GVTNLLEILTACGGSAEGISTYGALKKAVADAVIAELEPLQKRYADLAADPAHVTSVYEA
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GAARCREVTAPVLAAAQAAMGL
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHRQLSLLTPSGHLTLGNLLGALRPMAAAQRDASTPAACFYGIADLHAMTTPHEPARLRS
CCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
LTHETATLLLAAGLEESTLFVQSRVPAHAQLAYLLECTASTGELNRMIQFKEKGRDQPTT
HHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCH
RASLFTYPALMAADILLYRPRQVPVGADQRQHVELTRDLATRFNSTYGPVFTIPEITVPA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCEEECC
AGARVMRLDDPTVKMGKSAAETPGVVRLLDPPDVVRRKVARAVTDSDTGPDAVRADPNKP
CCCEEEEECCCHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GVTNLLEILTACGGSAEGISTYGALKKAVADAVIAELEPLQKRYADLAADPAHVTSVYEA
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GAARCREVTAPVLAAAQAAMGL
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]