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The map label for this gene is folB [H]

Identifier: 119714711

GI number: 119714711

Start: 478787

End: 479173

Strand: Direct

Name: folB [H]

Synonym: Noca_0447

Alternate gene names: 119714711

Gene position: 478787-479173 (Clockwise)

Preceding gene: 119714710

Following gene: 119714712

Centisome position: 9.6

GC content: 67.7

Gene sequence:

>387_bases
GTGACCGAACGGCCGACCGACGAGCTGAGCGTCACCGGCATCGCGTGCTACGGGCACCACGGCGTCTTCGACTTCGAGCG
ACGCGAGGGGCAGACGTTCGTCGTCGACCTCGTGCTGGGCGTCGACACCGCCCCCGCAGCGGCGTCCGACGACTTGCAAG
ACACCGTCGACTACGGGAGTCTCGTGGCTTCGGTGCAAGCCGCCGTGGAGAAGGATCCGGTCGACCTGATCGAGACCCTG
GCCCAGCGGATCGCGGGCGTCTGCCTCTTGGACGGCCGTGTTGAATGGGCGAGGGTGACGGTCCACAAGCCGGACGCACC
CATCGAAGCGACGTTCGCGGACGTCACGCTGACGATCACCCGGAGACGTGAGGGCACCCGTGACTGA

Upstream 100 bases:

>100_bases
ACCTGGCCCGGCATGCGGTGTGGGGCGTACGGGTGCACGACGTCCGAGCCTCCCGGGACGCGCTCCGCGTCGCCGAGCAG
CTGAGCGAGGAGGGTTCCAC

Downstream 100 bases:

>100_bases
GACCCCGAACCCGAACATCATCGACGCGGACACGCTGACCGGCGAGATGCGGCCGATCCGCCGTGCGGTGCTGGCACTCG
GGTCCAACCTGGGTGAGCGG

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MTERPTDELSVTGIACYGHHGVFDFERREGQTFVVDLVLGVDTAPAAASDDLQDTVDYGSLVASVQAAVEKDPVDLIETL
AQRIAGVCLLDGRVEWARVTVHKPDAPIEATFADVTLTITRRREGTRD

Sequences:

>Translated_128_residues
MTERPTDELSVTGIACYGHHGVFDFERREGQTFVVDLVLGVDTAPAAASDDLQDTVDYGSLVASVQAAVEKDPVDLIETL
AQRIAGVCLLDGRVEWARVTVHKPDAPIEATFADVTLTITRRREGTRD
>Mature_127_residues
TERPTDELSVTGIACYGHHGVFDFERREGQTFVVDLVLGVDTAPAAASDDLQDTVDYGSLVASVQAAVEKDPVDLIETLA
QRIAGVCLLDGRVEWARVTVHKPDAPIEATFADVTLTITRRREGTRD

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13913; Mature: 13781

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERPTDELSVTGIACYGHHGVFDFERREGQTFVVDLVLGVDTAPAAASDDLQDTVDYGS
CCCCCCCCEEEEEEEEECCCCCEEECCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHH
LVASVQAAVEKDPVDLIETLAQRIAGVCLLDGRVEWARVTVHKPDAPIEATFADVTLTIT
HHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCEEEEEEEEECCCCCCEEEEEEEEEEEE
RRREGTRD
ECCCCCCC
>Mature Secondary Structure 
TERPTDELSVTGIACYGHHGVFDFERREGQTFVVDLVLGVDTAPAAASDDLQDTVDYGS
CCCCCCCEEEEEEEEECCCCCEEECCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHH
LVASVQAAVEKDPVDLIETLAQRIAGVCLLDGRVEWARVTVHKPDAPIEATFADVTLTIT
HHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCEEEEEEEEECCCCCCEEEEEEEEEEEE
RRREGTRD
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]