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The map label for this gene is ubiE [C]

Identifier: 119714626

GI number: 119714626

Start: 385393

End: 386220

Strand: Reverse

Name: ubiE [C]

Synonym: Noca_0360

Alternate gene names: 119714626

Gene position: 386220-385393 (Counterclockwise)

Preceding gene: 119714627

Following gene: 119714625

Centisome position: 7.75

GC content: 73.43

Gene sequence:

>828_bases
ATGAGCGACCAGCCCGCCACCTCGCCCGCGCTCTCGTTCGGGGACGTCGCCGCCGCCTACGACCGCGGCCGGCCGACCTA
CCCGCGCGCGGCCGCCGCCTGGGCCGTGGGCGACCAGCCGACCACCGTGCTCGAGCTGGGCGCCGGGACCGGCAAGCTGA
CCGAGGTGCTCGTGTCGCTCGGCCACGACGTGCACGCCACCGACCCCGACGAGCAGATGCTGGCCGTCCTCCGCGAGCGG
CTGCCCGAGGTCCGCACCTCCGTCGCCGCGGCCGAGGACATCCCGGCGCCGGACGCGTCGTACGACGTCGTGGTGGCCGC
ACAGGCCTTCCACTGGTTCGACCACGAGCGCGCACTGCCCGAGATCGCCCGGGTCCTCAAGCCCGGCGGGCGTCTCGCCG
TCGTGTGGAACGCCCGCGACGAGCGGATCCCCTGGGTGCGCAGGCTCGGCCGGATCATCGGCAGCCAGGAGCAGTCGCGC
TCCGAGGGGCCGCTGGAGAACAGCACCCTCTTCGAAGCACTCGAGACCGAGTCCTTCCGCCACTGGCAGCTCGTGGATCG
TGACTCGATCCGGGACCTCGTGCTGTCCCGATCGAACGTCGCGACCCTCGACGAGACGGCGCGGGCCGACAAGCTCGCCG
AGGTCGTCGCCTTCTACGACGACTACGGCCGCGGGATGGACGGCATGCAGCTGCCGTACGTCGCCCGCTGCTTCCGCAGC
GCCCTCGTCGCGGGTGCCGTGACGGAGGACCCCGGCGCCGGCCCGGCGGCCGAGGCGCCCGTGACCGACGGCTCCGACAC
CGAGATGCTGCTCATCGACTTCCGCTGA

Upstream 100 bases:

>100_bases
GCGGCGGCGTACGCCGACGGGACACCCTCGAGGGAAGCCAAGCGGGACAAGGGGTCTGTGGTCACGTGGATCACCGTATC
CAGCAGGTAGCGTGGCCTCG

Downstream 100 bases:

>100_bases
CGGGAGGCGCTCGGTCAGTAGCGTCCGCGCATGAACGCCGCGCGCCCGAACCGACGCGTTCGGCTCCTGGTCGTCCTGTG
CGTGGCGCTGGCCGCGGGCT

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSDQPATSPALSFGDVAAAYDRGRPTYPRAAAAWAVGDQPTTVLELGAGTGKLTEVLVSLGHDVHATDPDEQMLAVLRER
LPEVRTSVAAAEDIPAPDASYDVVVAAQAFHWFDHERALPEIARVLKPGGRLAVVWNARDERIPWVRRLGRIIGSQEQSR
SEGPLENSTLFEALETESFRHWQLVDRDSIRDLVLSRSNVATLDETARADKLAEVVAFYDDYGRGMDGMQLPYVARCFRS
ALVAGAVTEDPGAGPAAEAPVTDGSDTEMLLIDFR

Sequences:

>Translated_275_residues
MSDQPATSPALSFGDVAAAYDRGRPTYPRAAAAWAVGDQPTTVLELGAGTGKLTEVLVSLGHDVHATDPDEQMLAVLRER
LPEVRTSVAAAEDIPAPDASYDVVVAAQAFHWFDHERALPEIARVLKPGGRLAVVWNARDERIPWVRRLGRIIGSQEQSR
SEGPLENSTLFEALETESFRHWQLVDRDSIRDLVLSRSNVATLDETARADKLAEVVAFYDDYGRGMDGMQLPYVARCFRS
ALVAGAVTEDPGAGPAAEAPVTDGSDTEMLLIDFR
>Mature_274_residues
SDQPATSPALSFGDVAAAYDRGRPTYPRAAAAWAVGDQPTTVLELGAGTGKLTEVLVSLGHDVHATDPDEQMLAVLRERL
PEVRTSVAAAEDIPAPDASYDVVVAAQAFHWFDHERALPEIARVLKPGGRLAVVWNARDERIPWVRRLGRIIGSQEQSRS
EGPLENSTLFEALETESFRHWQLVDRDSIRDLVLSRSNVATLDETARADKLAEVVAFYDDYGRGMDGMQLPYVARCFRSA
LVAGAVTEDPGAGPAAEAPVTDGSDTEMLLIDFR

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29912; Mature: 29780

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQPATSPALSFGDVAAAYDRGRPTYPRAAAAWAVGDQPTTVLELGAGTGKLTEVLVSL
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHEEECCCCCCEEEEECCCCHHHHHHHHHH
GHDVHATDPDEQMLAVLRERLPEVRTSVAAAEDIPAPDASYDVVVAAQAFHWFDHERALP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHH
EIARVLKPGGRLAVVWNARDERIPWVRRLGRIIGSQEQSRSEGPLENSTLFEALETESFR
HHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCC
HWQLVDRDSIRDLVLSRSNVATLDETARADKLAEVVAFYDDYGRGMDGMQLPYVARCFRS
CEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ALVAGAVTEDPGAGPAAEAPVTDGSDTEMLLIDFR
HHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
SDQPATSPALSFGDVAAAYDRGRPTYPRAAAAWAVGDQPTTVLELGAGTGKLTEVLVSL
CCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHEEECCCCCCEEEEECCCCHHHHHHHHHH
GHDVHATDPDEQMLAVLRERLPEVRTSVAAAEDIPAPDASYDVVVAAQAFHWFDHERALP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHH
EIARVLKPGGRLAVVWNARDERIPWVRRLGRIIGSQEQSRSEGPLENSTLFEALETESFR
HHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCC
HWQLVDRDSIRDLVLSRSNVATLDETARADKLAEVVAFYDDYGRGMDGMQLPYVARCFRS
CEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ALVAGAVTEDPGAGPAAEAPVTDGSDTEMLLIDFR
HHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]