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The map label for this gene is phoP [H]

Identifier: 119714578

GI number: 119714578

Start: 332756

End: 333457

Strand: Direct

Name: phoP [H]

Synonym: Noca_0312

Alternate gene names: 119714578

Gene position: 332756-333457 (Clockwise)

Preceding gene: 119714576

Following gene: 119714579

Centisome position: 6.67

GC content: 72.51

Gene sequence:

>702_bases
ATGTCGGGTCGGCGCGCCCTGGTGGTCGAGGACGAGCCGGAGCTGGCACGGCTGGTCGGCAGCTACCTCGAGCGCGACGG
GTTCGCGGTCACGATCGTCCACGACGGTCTCGAGGCGGTGGCGCGCTCGCGCGAGGTCGACCCGGACGTGGTGGTCCTCG
ACCTGGGTCTGCCGGGCCTCGACGGTGTGGAGGTGTGCCGCCGCCTGCGGACGTTCTCCGATGGGTACGTCGTGATGCTC
ACCGCCCGCAGCGACGAGGTCGACACGCTGATCGGTCTGTCGGTCGGCGCCGACGACTACCTGACGAAGCCGTTCAGCCC
GCGGGAGCTGGTCGCTCGCGTCCAGGCGATGCTCCGGCGTCCGCGGCCGCTCGGCCACATGGATGCCGACGCCGGGGAGG
CCCTCTCGTTCGGGGACCTGACCATCGAGCTGGCCGGGCGCGACGTGTGGCTCGAGGACCGCGCGGTCCCGCTCACCCGC
ACCGAGTTCGACCTGCTTGCGACCCTGGCCCAGCGGCCGGGCATGGCCTTCAGCCGTCGCCAGCTGATCGACGCGGTCTG
GGGACCCGCTTGGGTCGGCGACGAGCACCTCGTCGACGTCCACGTCGGCCACCTGCGGCACAAGCTCGGCGACTCCGCGG
CCGAGGGCAGGTACGTCCGGACGGTCCGGGGAATCGGCTACCGGATGGGGCGGGGGGCATGA

Upstream 100 bases:

>100_bases
GCCCGCGGGCTGGCACCATGGCGACATGGGCGATCAGGGCACCCCAGGGACGCCGGGCGGTCCGGGCCGCCTGCTGCGCG
CGGAGGAGCCCACCGGGCCC

Downstream 100 bases:

>100_bases
CCCGGCCGCGGTTCGCAGCGCGGCTGCTCGTCGCCCAGGCCCTGGTGCTGCTGGCCGGGGCGCTCACCACCTGGCTGGTG
GCGTCGGTGGTCGGCCCCGG

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSGRRALVVEDEPELARLVGSYLERDGFAVTIVHDGLEAVARSREVDPDVVVLDLGLPGLDGVEVCRRLRTFSDGYVVML
TARSDEVDTLIGLSVGADDYLTKPFSPRELVARVQAMLRRPRPLGHMDADAGEALSFGDLTIELAGRDVWLEDRAVPLTR
TEFDLLATLAQRPGMAFSRRQLIDAVWGPAWVGDEHLVDVHVGHLRHKLGDSAAEGRYVRTVRGIGYRMGRGA

Sequences:

>Translated_233_residues
MSGRRALVVEDEPELARLVGSYLERDGFAVTIVHDGLEAVARSREVDPDVVVLDLGLPGLDGVEVCRRLRTFSDGYVVML
TARSDEVDTLIGLSVGADDYLTKPFSPRELVARVQAMLRRPRPLGHMDADAGEALSFGDLTIELAGRDVWLEDRAVPLTR
TEFDLLATLAQRPGMAFSRRQLIDAVWGPAWVGDEHLVDVHVGHLRHKLGDSAAEGRYVRTVRGIGYRMGRGA
>Mature_232_residues
SGRRALVVEDEPELARLVGSYLERDGFAVTIVHDGLEAVARSREVDPDVVVLDLGLPGLDGVEVCRRLRTFSDGYVVMLT
ARSDEVDTLIGLSVGADDYLTKPFSPRELVARVQAMLRRPRPLGHMDADAGEALSFGDLTIELAGRDVWLEDRAVPLTRT
EFDLLATLAQRPGMAFSRRQLIDAVWGPAWVGDEHLVDVHVGHLRHKLGDSAAEGRYVRTVRGIGYRMGRGA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=41.4096916299559, Blast_Score=177, Evalue=4e-46,
Organism=Escherichia coli, GI1790860, Length=239, Percent_Identity=40.1673640167364, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=42.5438596491228, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=39.2070484581498, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=39.3939393939394, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.8421052631579, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.5291479820628, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=31.4655172413793, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.9285714285714, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI145693140, Length=227, Percent_Identity=34.3612334801762, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=32.7433628318584, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=34.070796460177, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.0396475770925, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787229, Length=215, Percent_Identity=33.0232558139535, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=31.6239316239316, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25626; Mature: 25494

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRRALVVEDEPELARLVGSYLERDGFAVTIVHDGLEAVARSREVDPDVVVLDLGLPGL
CCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCEEEEECCCCCC
DGVEVCRRLRTFSDGYVVMLTARSDEVDTLIGLSVGADDYLTKPFSPRELVARVQAMLRR
CHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCHHHCCCCCHHHHHHHHHHHHHC
PRPLGHMDADAGEALSFGDLTIELAGRDVWLEDRAVPLTRTEFDLLATLAQRPGMAFSRR
CCCCCCCCCCCCCEEEECCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHH
QLIDAVWGPAWVGDEHLVDVHVGHLRHKLGDSAAEGRYVRTVRGIGYRMGRGA
HHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCC
>Mature Secondary Structure 
SGRRALVVEDEPELARLVGSYLERDGFAVTIVHDGLEAVARSREVDPDVVVLDLGLPGL
CCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCEEEEECCCCCC
DGVEVCRRLRTFSDGYVVMLTARSDEVDTLIGLSVGADDYLTKPFSPRELVARVQAMLRR
CHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCHHHCCCCCHHHHHHHHHHHHHC
PRPLGHMDADAGEALSFGDLTIELAGRDVWLEDRAVPLTRTEFDLLATLAQRPGMAFSRR
CCCCCCCCCCCCCEEEECCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHH
QLIDAVWGPAWVGDEHLVDVHVGHLRHKLGDSAAEGRYVRTVRGIGYRMGRGA
HHHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]