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The map label for this gene is tadA [H]

Identifier: 119714544

GI number: 119714544

Start: 298809

End: 299240

Strand: Direct

Name: tadA [H]

Synonym: Noca_0277

Alternate gene names: 119714544

Gene position: 298809-299240 (Clockwise)

Preceding gene: 119714543

Following gene: 119714545

Centisome position: 5.99

GC content: 75.69

Gene sequence:

>432_bases
ATGCGGACCGCCCTCGACGAGGCACGCGCCGCCCTGGCGTCCGGAGACGTGCCGATCGGCGCGGTGGTGCTGGACCCGGA
CGGTACGCCGGTGGCGCGCGGTCGCAACGTGCGCGAGGCCGACCACGACCCCACCGGGCATGCCGAGGTGGTGGCGCTCC
GCGCGGCCGCGCGCGCCCGGGGCGAGTGGCGGCTCGAGGGGCACACCCTCGTCGTCACCCTCGAGCCGTGCACCATGTGC
GCCGGCGCCGCCGTGCTGAGCCGGGTCGAGCGGATCGTGTTCGGCGCCTGGGACCCCAAGGCCGGAGCCGTCGGCAGCCT
CTGGGACGTGGTCCGCGACCGCCGCCTCAACCACCGGCCCGAGGTCATCAGCGGCGTGCTCGCCGAGGAGTCGGCCGGGC
TCCTCGAGGACTTCTTCCTCACTCAGCGCTGA

Upstream 100 bases:

>100_bases
AGATGCTCTCCGACGTCGCGCGGCGGCTGGGCTTCGGCAAGCTGTTCGACGACGCCGTCGGCCTCACCTCCGCGTGACCA
CCGGCCACTGGGACGGCCCG

Downstream 100 bases:

>100_bases
GTCCGGCGCCGCGGGGGGCACTGCGGTCATGATCTGACCTGATGCACTCCTACCGTGGCGCCATGGACTACAAGATCGAG
CTCATCCCCCTCGCCGTTCG

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MRTALDEARAALASGDVPIGAVVLDPDGTPVARGRNVREADHDPTGHAEVVALRAAARARGEWRLEGHTLVVTLEPCTMC
AGAAVLSRVERIVFGAWDPKAGAVGSLWDVVRDRRLNHRPEVISGVLAEESAGLLEDFFLTQR

Sequences:

>Translated_143_residues
MRTALDEARAALASGDVPIGAVVLDPDGTPVARGRNVREADHDPTGHAEVVALRAAARARGEWRLEGHTLVVTLEPCTMC
AGAAVLSRVERIVFGAWDPKAGAVGSLWDVVRDRRLNHRPEVISGVLAEESAGLLEDFFLTQR
>Mature_143_residues
MRTALDEARAALASGDVPIGAVVLDPDGTPVARGRNVREADHDPTGHAEVVALRAAARARGEWRLEGHTLVVTLEPCTMC
AGAAVLSRVERIVFGAWDPKAGAVGSLWDVVRDRRLNHRPEVISGVLAEESAGLLEDFFLTQR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=148, Percent_Identity=31.7567567567568, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=48.2517482517483, Blast_Score=125, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541138, Length=142, Percent_Identity=33.8028169014084, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=129, Percent_Identity=36.4341085271318, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=106, Percent_Identity=38.6792452830189, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=36.551724137931, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15328; Mature: 15328

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTALDEARAALASGDVPIGAVVLDPDGTPVARGRNVREADHDPTGHAEVVALRAAARAR
CCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
GEWRLEGHTLVVTLEPCTMCAGAAVLSRVERIVFGAWDPKAGAVGSLWDVVRDRRLNHRP
CCEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCH
EVISGVLAEESAGLLEDFFLTQR
HHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MRTALDEARAALASGDVPIGAVVLDPDGTPVARGRNVREADHDPTGHAEVVALRAAARAR
CCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
GEWRLEGHTLVVTLEPCTMCAGAAVLSRVERIVFGAWDPKAGAVGSLWDVVRDRRLNHRP
CCEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCH
EVISGVLAEESAGLLEDFFLTQR
HHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]