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The map label for this gene is pntB [H]

Identifier: 119714528

GI number: 119714528

Start: 280460

End: 281875

Strand: Direct

Name: pntB [H]

Synonym: Noca_0261

Alternate gene names: 119714528

Gene position: 280460-281875 (Clockwise)

Preceding gene: 119714527

Following gene: 119714530

Centisome position: 5.63

GC content: 69.0

Gene sequence:

>1416_bases
ATGAGTGCCGTAAGCATCTCCGTCGGCGCCTACCTGGTCGCCTCGCTCCTGTTCATCCTCAGCCTCGCCGGCCTGTCGCG
CCACGAGAGCGCCCGCAACGGCGTCAACTACGGCATCGCCGGGATGGCGTTGGCGCTGGCCGCCACCGTCGGCCTGCTCG
TCCACGACACCGACGAGGCGCTTCCGCTGGTGCTCCTCGTCGTGGCCATGACGGTCGGGGCGGCCATCGGCCTGTGGCGG
GCCCGGGTCGTCGCGATGACCGGCATGCCCGAGCTGATCGCGCTGCTGCACTCGTTCGTCGGTCTGGCCGCGGTCCTCGT
GGGCTGGAACGGCTACCTGCACGATGAGGGGCTCACCGGCTCGTTGTTCCGGATCCACAGCGCCGAGGTCGTCATCGGCG
TCTTCATCGGCGCCGTGACGTTCACCGGCTCGATCGTCGCGAACCTCAAGCTCTCGGCGCGCATGAAGTCGGCGCCGCTG
ATGCTGCCCGGGAAGAACGCGATCAACCTCGGCGCCCTGGCGGTCTTCGCGGCTCTCACCGTGTGGTTCACCGCCTCGCC
GAACCTCGGCGTGCTGATCGCCGTGACCGCGGTCGCACTCGCCCTGGGCTGGCACCTGGTCGCCTCCATCGGCGGCGGCG
ACATGCCGGTCGTGGTGTCGATGCTGAACAGCTACTCGGGCTGGGCCGCGGCGGCGTCCGGGTTCCTGCTCGACAACAAC
CTGCTCATCGTGACCGGCGCGCTCGTCGGGTCGTCCGGTGCCTACCTGTCCTACATCATGTGCGAGGCGATGAACCGCTC
GTTCATCTCGGTGATCGCGGGCGGCTTCGGCATCGAGGTCGCCGCGTCGGGGGACACCGACTACGGCGAGCACCACGAGA
TCTCGGCCGAGGAGGTCGCCGAGCTCCTTGCCGACGCCTCAAGCGTGATCATCACCCCCGGCTACGGCATGGCGGTCGCG
CAGGCGCAGTACCCGGTCGCCGAGCTCACCAGCAAGCTGCGGGCCCGCGGCGTCGACGTCCGCTTCGGCATCCACCCCGT
CGCCGGACGGCTCCCGGGGCACATGAACGTGCTGCTCGCCGAGGCCAAGGTGCCCTACGACGTCGTGCTGGAGATGGACG
AGATCAACGACGACTTCCCGAGCACCGACGTCGTCCTGGTCATCGGCGCGAACGACACCGTCAACCCCGCCGCCCTGGAG
GAGCCGGGCAGCCCGATCGCCGGCATGCCGGTGCTCCACGTGTGGGAGGCCAAGGACGTCATCGTCTTCAAGCGCTCGAT
GGCCGTGGGCTACGCCGGCGTGCAGAACCCGCTCTTCTTCCGCGACAACACCCACATGCTGTTCGGTGACGCCAAGGATC
GGGTCGAGGACATCGTGCGGCAGCTCTCCGACATCCCCCAGCAGGTCTCGCGCTGA

Upstream 100 bases:

>100_bases
CCCTGTCCTTCGTCGCAGTGCTCCTGGCCAGCATCAACGTGTTCGGCGGCTTCGCCGTGACCCGCCGGATGCTCGGCATG
TTCCGGAAGGCGGACCAGTG

Downstream 100 bases:

>100_bases
CGCGGTCGGTGTGGCGGTCCCGGGATCGCCACACCGATCGGTGGGCGCGGAGTGTCAGTCCAGACCGGCGGCCGATCCGC
GGTGGCGGGCGGGCTTCCCG

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSAVSISVGAYLVASLLFILSLAGLSRHESARNGVNYGIAGMALALAATVGLLVHDTDEALPLVLLVVAMTVGAAIGLWR
ARVVAMTGMPELIALLHSFVGLAAVLVGWNGYLHDEGLTGSLFRIHSAEVVIGVFIGAVTFTGSIVANLKLSARMKSAPL
MLPGKNAINLGALAVFAALTVWFTASPNLGVLIAVTAVALALGWHLVASIGGGDMPVVVSMLNSYSGWAAAASGFLLDNN
LLIVTGALVGSSGAYLSYIMCEAMNRSFISVIAGGFGIEVAASGDTDYGEHHEISAEEVAELLADASSVIITPGYGMAVA
QAQYPVAELTSKLRARGVDVRFGIHPVAGRLPGHMNVLLAEAKVPYDVVLEMDEINDDFPSTDVVLVIGANDTVNPAALE
EPGSPIAGMPVLHVWEAKDVIVFKRSMAVGYAGVQNPLFFRDNTHMLFGDAKDRVEDIVRQLSDIPQQVSR

Sequences:

>Translated_471_residues
MSAVSISVGAYLVASLLFILSLAGLSRHESARNGVNYGIAGMALALAATVGLLVHDTDEALPLVLLVVAMTVGAAIGLWR
ARVVAMTGMPELIALLHSFVGLAAVLVGWNGYLHDEGLTGSLFRIHSAEVVIGVFIGAVTFTGSIVANLKLSARMKSAPL
MLPGKNAINLGALAVFAALTVWFTASPNLGVLIAVTAVALALGWHLVASIGGGDMPVVVSMLNSYSGWAAAASGFLLDNN
LLIVTGALVGSSGAYLSYIMCEAMNRSFISVIAGGFGIEVAASGDTDYGEHHEISAEEVAELLADASSVIITPGYGMAVA
QAQYPVAELTSKLRARGVDVRFGIHPVAGRLPGHMNVLLAEAKVPYDVVLEMDEINDDFPSTDVVLVIGANDTVNPAALE
EPGSPIAGMPVLHVWEAKDVIVFKRSMAVGYAGVQNPLFFRDNTHMLFGDAKDRVEDIVRQLSDIPQQVSR
>Mature_470_residues
SAVSISVGAYLVASLLFILSLAGLSRHESARNGVNYGIAGMALALAATVGLLVHDTDEALPLVLLVVAMTVGAAIGLWRA
RVVAMTGMPELIALLHSFVGLAAVLVGWNGYLHDEGLTGSLFRIHSAEVVIGVFIGAVTFTGSIVANLKLSARMKSAPLM
LPGKNAINLGALAVFAALTVWFTASPNLGVLIAVTAVALALGWHLVASIGGGDMPVVVSMLNSYSGWAAAASGFLLDNNL
LIVTGALVGSSGAYLSYIMCEAMNRSFISVIAGGFGIEVAASGDTDYGEHHEISAEEVAELLADASSVIITPGYGMAVAQ
AQYPVAELTSKLRARGVDVRFGIHPVAGRLPGHMNVLLAEAKVPYDVVLEMDEINDDFPSTDVVLVIGANDTVNPAALEE
PGSPIAGMPVLHVWEAKDVIVFKRSMAVGYAGVQNPLFFRDNTHMLFGDAKDRVEDIVRQLSDIPQQVSR

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=466, Percent_Identity=49.7854077253219, Blast_Score=427, Evalue=1e-119,
Organism=Homo sapiens, GI122939153, Length=466, Percent_Identity=49.7854077253219, Blast_Score=427, Evalue=1e-119,
Organism=Escherichia coli, GI1787886, Length=459, Percent_Identity=68.4095860566449, Blast_Score=612, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI17550456, Length=469, Percent_Identity=47.3347547974414, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49212; Mature: 49081

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVSISVGAYLVASLLFILSLAGLSRHESARNGVNYGIAGMALALAATVGLLVHDTDEA
CCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCCHH
LPLVLLVVAMTVGAAIGLWRARVVAMTGMPELIALLHSFVGLAAVLVGWNGYLHDEGLTG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
SLFRIHSAEVVIGVFIGAVTFTGSIVANLKLSARMKSAPLMLPGKNAINLGALAVFAALT
CEEEEECHHHHHHHHHHHHHHHCHHEEEEEEEHHHCCCCEECCCCCCCHHHHHHHHHHHH
VWFTASPNLGVLIAVTAVALALGWHLVASIGGGDMPVVVSMLNSYSGWAAAASGFLLDNN
HHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCEEEECC
LLIVTGALVGSSGAYLSYIMCEAMNRSFISVIAGGFGIEVAASGDTDYGEHHEISAEEVA
EEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHH
ELLADASSVIITPGYGMAVAQAQYPVAELTSKLRARGVDVRFGIHPVAGRLPGHMNVLLA
HHHHCCCCEEEECCCCCEEHHCCCCHHHHHHHHHHCCCEEEECCCHHCCCCCCCCEEEEE
EAKVPYDVVLEMDEINDDFPSTDVVLVIGANDTVNPAALEEPGSPIAGMPVLHVWEAKDV
ECCCCCEEEEEEHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCE
IVFKRSMAVGYAGVQNPLFFRDNTHMLFGDAKDRVEDIVRQLSDIPQQVSR
EEEEHHHHHCCCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAVSISVGAYLVASLLFILSLAGLSRHESARNGVNYGIAGMALALAATVGLLVHDTDEA
CEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCCHH
LPLVLLVVAMTVGAAIGLWRARVVAMTGMPELIALLHSFVGLAAVLVGWNGYLHDEGLTG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
SLFRIHSAEVVIGVFIGAVTFTGSIVANLKLSARMKSAPLMLPGKNAINLGALAVFAALT
CEEEEECHHHHHHHHHHHHHHHCHHEEEEEEEHHHCCCCEECCCCCCCHHHHHHHHHHHH
VWFTASPNLGVLIAVTAVALALGWHLVASIGGGDMPVVVSMLNSYSGWAAAASGFLLDNN
HHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCEEEECC
LLIVTGALVGSSGAYLSYIMCEAMNRSFISVIAGGFGIEVAASGDTDYGEHHEISAEEVA
EEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHH
ELLADASSVIITPGYGMAVAQAQYPVAELTSKLRARGVDVRFGIHPVAGRLPGHMNVLLA
HHHHCCCCEEEECCCCCEEHHCCCCHHHHHHHHHHCCCEEEECCCHHCCCCCCCCEEEEE
EAKVPYDVVLEMDEINDDFPSTDVVLVIGANDTVNPAALEEPGSPIAGMPVLHVWEAKDV
ECCCCCEEEEEEHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCE
IVFKRSMAVGYAGVQNPLFFRDNTHMLFGDAKDRVEDIVRQLSDIPQQVSR
EEEEHHHHHCCCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]