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The map label for this gene is cutS [H]

Identifier: 119714490

GI number: 119714490

Start: 239725

End: 240201

Strand: Direct

Name: cutS [H]

Synonym: Noca_0223

Alternate gene names: 119714490

Gene position: 239725-240201 (Clockwise)

Preceding gene: 119714489

Following gene: 119714491

Centisome position: 4.81

GC content: 70.02

Gene sequence:

>477_bases
GTGGAGGTGACCCTCACGGTGAACGGCGAGGTCGTCACCCGCGACGTGGAGGCGCGCCTGCTGCTCGTGCACTTCCTGCG
CGACGACCTCGGCCTGACCGGTACGCACTGGGGCTGCGACACCAGTAACTGCGGCAGCTGCGTGGTCCTGTACGACGACG
AGCCGGTCAAGTCGTGCACCGTGCTCACCGCGATGGCCGCCGGTCATGACGTCCGCACCGTCGAGGACCTCGAGCAGGAC
GGGGAGCTCGACCCGGTGCAGCAGGGCTTCATGGAGTGCCACGGCCTCCAGTGCGGCTTCTGCACCTCCGGGATGCTGAT
GTCCGCCCGGGCGCTGCTCGACCGCGACCCGGACCCGAGCGAGGAGGACATCCGGGAGGCGATCTCGGGACAGATCTGCC
GGTGCACCGGCTACGCCTCGATCGTCCGCTCCGTGCGCTGGGCCGCCGACCACCCCGAGGGGAGGATCGAGGCATGA

Upstream 100 bases:

>100_bases
GACCGGTCACCGACGGCCGCGGGAGCGCGGACTACAAGCGCCACCTGGCCGGGGAGCTCACCCGGCGTACGCTGCGCACG
GCCTGGGAGCGGGTGGTCAC

Downstream 100 bases:

>100_bases
CCGCGACCGTCCCGATCGGGCACGGCCGGATGCTCCGCAAGGAGGACCGGCGGTTCGTGCGCGGCCGCGGGAAGTACCTC
GACGACATCGCGCTGCCGGG

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MEVTLTVNGEVVTRDVEARLLLVHFLRDDLGLTGTHWGCDTSNCGSCVVLYDDEPVKSCTVLTAMAAGHDVRTVEDLEQD
GELDPVQQGFMECHGLQCGFCTSGMLMSARALLDRDPDPSEEDIREAISGQICRCTGYASIVRSVRWAADHPEGRIEA

Sequences:

>Translated_158_residues
MEVTLTVNGEVVTRDVEARLLLVHFLRDDLGLTGTHWGCDTSNCGSCVVLYDDEPVKSCTVLTAMAAGHDVRTVEDLEQD
GELDPVQQGFMECHGLQCGFCTSGMLMSARALLDRDPDPSEEDIREAISGQICRCTGYASIVRSVRWAADHPEGRIEA
>Mature_158_residues
MEVTLTVNGEVVTRDVEARLLLVHFLRDDLGLTGTHWGCDTSNCGSCVVLYDDEPVKSCTVLTAMAAGHDVRTVEDLEQD
GELDPVQQGFMECHGLQCGFCTSGMLMSARALLDRDPDPSEEDIREAISGQICRCTGYASIVRSVRWAADHPEGRIEA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=157, Percent_Identity=35.6687898089172, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI91823271, Length=152, Percent_Identity=38.8157894736842, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=36.5853658536585, Blast_Score=113, Evalue=5e-27,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=37.3239436619718, Blast_Score=99, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=38.255033557047, Blast_Score=106, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=37.012987012987, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=37.012987012987, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17737937, Length=158, Percent_Identity=37.3417721518987, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=31.6129032258064, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=32.2981366459627, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=28.3870967741935, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=32.2981366459627, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=32.2981366459627, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17261; Mature: 17261

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTLTVNGEVVTRDVEARLLLVHFLRDDLGLTGTHWGCDTSNCGSCVVLYDDEPVKSCT
CEEEEEECCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHH
VLTAMAAGHDVRTVEDLEQDGELDPVQQGFMECHGLQCGFCTSGMLMSARALLDRDPDPS
HHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
EEDIREAISGQICRCTGYASIVRSVRWAADHPEGRIEA
HHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEVTLTVNGEVVTRDVEARLLLVHFLRDDLGLTGTHWGCDTSNCGSCVVLYDDEPVKSCT
CEEEEEECCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHH
VLTAMAAGHDVRTVEDLEQDGELDPVQQGFMECHGLQCGFCTSGMLMSARALLDRDPDPS
HHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
EEDIREAISGQICRCTGYASIVRSVRWAADHPEGRIEA
HHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]